Aphasia: Difference between revisions

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== Definition ==
Aphasia is a condition, where a person has difficulty with their language or speech which is most commonly caused by damage to the left side of the [[Brain Anatomy|brain]] for example, after a [[stroke]], head injury or brain tumor.<ref>NHS choices. NHS; 2021 March 23. Available from: https://www.nhs.uk/conditions/aphasia/</ref><ref>Damasio AR. Aphasia. New England Journal of Medicine. 1992 Feb 20;326(8):531-9.</ref><ref>Berthier ML. Poststroke aphasia. Drugs & aging. 2005 Feb;22(2):163-82.</ref><ref>Geschwind N. Aphasia. New England Journal of Medicine. 1971 Mar 25;284(12):654-6.</ref>
== Introduction ==
== Introduction ==
Aphasia is a condition resulting from damage to areas of the [[Brain Anatomy|brain]] responsible for language, which for most people is located in the left hemisphere of the brain<ref name=":0">National Institute on Deafness and Other Communication Disorders, Aphasia. Available from: https://www.nidcd.nih.gov/health/aphasia (accessed 28 July, 2021)</ref>. The  condition presents as an impairment to comprehension or formulation of language and is often caused by diseases and disorders affecting the brain, with cerebrovascular accident being the most common cause<ref name=":1">Le H, Lui MY. [https://www.ncbi.nlm.nih.gov/books/NBK559315/ Aphasia]. StatPearls [Internet]. 2021 Jun 13.</ref>.
As mentioned above aphasia is a condition resulting from damage to areas of the [[Brain Anatomy|brain]] responsible for language, which for most people is located in the left hemisphere of the brain<ref name=":0">National Institute on Deafness and Other Communication Disorders, Aphasia. Available from: https://www.nidcd.nih.gov/health/aphasia (accessed 28 July, 2021)</ref>. The  condition presents as an impairment to comprehension or formulation of language and is often caused by diseases and disorders affecting the brain, with cerebrovascular accident being the most common cause<ref name=":1">Le H, Lui MY. [https://www.ncbi.nlm.nih.gov/books/NBK559315/ Aphasia]. StatPearls [Internet]. 2021 Jun 13.</ref>.
{{#ev:youtube|GsVhbmecJA|300}}<ref>TED-Ed. Aphasia: The disorder that makes you lose your words - Susan Wortman-Jutt. Available from: http://www.youtu.be/-GsVhbmecJA [last accessed 29/7/2021]</ref>
{{#ev:youtube|GsVhbmecJA|300}}<ref>TED-Ed. Aphasia: The disorder that makes you lose your words - Susan Wortman-Jutt. Available from: http://www.youtu.be/-GsVhbmecJA [last accessed 29/7/2021]</ref>


== Anatomy ==
== Anatomy ==
Areas of the brain responsible for language:
'''Areas of the brain responsible for language:'''


* Werncike's area
* Werncike's area
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The Wernicke's area is located in the temporal lobe and is responsible for processing visual and auditory information. It is the center for comprehension and planning of words. Broca's area on the other hand is located in the frontal lobe of the brain. It is responsible for motor execution of speech and sentence formation. While the arcuate fasciculus is the neural connection between both areas<ref>Ochfeld E, Newhart M, Molitoris J, Leigh R, Cloutman L, Davis C, Crinion J, Hillis AE. [https://doi.org/10.1161/STROKEAHA.109.570374 Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke.] Stroke. 2010 Feb 1;41(2):325-30.</ref>.
The Wernicke's area is located in the temporal lobe and is responsible for processing visual and auditory information. It is the center for comprehension and planning of words. Broca's area on the other hand is located in the frontal lobe of the brain. It is responsible for motor execution of speech and sentence formation. While the arcuate fasciculus is the neural connection between both areas<ref>Ochfeld E, Newhart M, Molitoris J, Leigh R, Cloutman L, Davis C, Crinion J, Hillis AE. [https://doi.org/10.1161/STROKEAHA.109.570374 Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke.] Stroke. 2010 Feb 1;41(2):325-30.</ref>.


== Causes of Aphasia ==
== Symptoms of aphasia ==
Aphasia can occur from a number of brain injuries and conditions such as:
 
== Causes of aphasia ==
'''Aphasia can occur from a number of brain injuries and conditions such as:'''


* [[Stroke]]
*[[Stroke]]
* [[Traumatic Brain Injury|Traumatic brain injury]]
*[[Traumatic Brain Injury|Traumatic brain injury]]
* Severe blows to the head
* Severe blows to the head
* [[Brain Tumors|Brain tumours]]
*[[Brain Tumors|Brain tumors]]
* Gunshot wounds
* Gunshot wounds
* [[Brain Metastasis|Brain infections]]
*[[Brain Metastasis|Brain infections]]
* [[Alzheimer's Disease|Alzheimer's disease]]<ref name=":0" />
*[[Alzheimer's Disease|Alzheimer's disease]]<ref name=":0" />
* Frontotemporal lobar degeneration
* Frontotemporal lobar degeneration
* Vascular [[dementia]]
* Vascular [[dementia]]
* [[Pick's Disease|Pick disease]]
*[[Pick's Disease|Pick disease]]


== Types of Aphasia ==
== Types of Aphasia ==
Aphasia can be broadly classified as either fluent or non-fluent.<ref>Aphasia. NIH. Available from https://www.nidcd.nih.gov/health/aphasia [last accessed 11/11/2021]</ref>  
'''<u>Aphasia can be broadly classified as either fluent or non-fluent.</u>'''<ref>Aphasia. NIH. Available from https://www.nidcd.nih.gov/health/aphasia [last accessed 11/11/2021]</ref>  


# Non-Fluent aphasia includes:
# '''Non-Fluent aphasia includes:'''
#* Broca's
#* Broca's
#* Transcortical motor
#* Transcortical motor
#* Mixed transcortical
#* Mixed transcortical
#* Global
#* Global
# Fluent aphasia types are:
# '''Fluent aphasia types are:'''
#* Wernicke's
#* Wernicke's
#* Transcortical sensory
#* Transcortical sensory
#* Conduction
#* Conduction
#* Anomic<ref name=":1" />
#* Anomic<ref name=":1" />
The most common types of aphasia include:
'''<u>The most common types of aphasia include:</u>'''
* '''Broca's aphasia'''.  
* '''Broca's aphasia'''.  
** Occurs from damage to the [[Frontal Lobe|frontal lobe.]]
** Occurs from damage to the [[Frontal Lobe|frontal lobe.]]
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** May have trouble understanding simple words and sentences.
** May have trouble understanding simple words and sentences.
** May be limited in their ability to speak and comprehend language.<ref name=":0" />
** May be limited in their ability to speak and comprehend language.<ref name=":0" />
Other forms of aphasia are<ref name=":1" />:
'''<u>Other forms of aphasia are:</u>'''<ref name=":1" />


* ''Conduction Aphasia'' is caused by lesion located in the arcuate fasciculus. Patients with this type of aphasia experience difficulties with or are unable to repeat words spoken to them. They realise the errors they make and endeavour to correct them.
* '''''Conduction Aphasia''''' is caused by lesion located in the arcuate fasciculus. Patients with this type of aphasia experience difficulties with or are unable to repeat words spoken to them. They realise the errors they make and endeavour to correct them.
* ''Transcortical Sensory Aphasia'' is caused by lesions around but not affecting the Wernicke's area. Patients may be able to repeat speech fluently but have difficulties with comprehension.
* '''''Transcortical Sensory Aphasia''''' is caused by lesions around but not affecting the Wernicke's area. Patients may be able to repeat speech fluently but have difficulties with comprehension.
* ''Transcortical Motor Aphasia'' is from lesions around but that do not affect the Broca's area. Patients have a tendency to remain silent and may repeat one to two words. They may also be able to repeat long complex phrases although their speech may not be fluent.
* '''''Transcortical Motor Aphasia''''' is from lesions around but that do not affect the Broca's area. Patients have a tendency to remain silent and may repeat one to two words. They may also be able to repeat long complex phrases although their speech may not be fluent.
* ''Mixed Transcortical Aphasia'' results from lesions around the language areas of the brain but that do not affect them. Patients in this category have severe speaking and comprehension impairment but can repeat long, complex sentences.
* '''''Mixed Transcortical Aphasia''''' results from lesions around the language areas of the brain but that do not affect them. Patients in this category have severe speaking and comprehension impairment but can repeat long, complex sentences.
* ''Anomia'' is the mildest form of aphasia  and is from damage to angular gyrus. It is characterised by patients having difficulties with finding words.
* '''''Anomia''''' is the mildest form of aphasia  and is from damage to angular gyrus. It is characterised by patients having difficulties with finding words.


== Differential Diagnoses ==
== Differential Diagnoses ==

Revision as of 18:10, 27 June 2022

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Definition[edit | edit source]

Aphasia is a condition, where a person has difficulty with their language or speech which is most commonly caused by damage to the left side of the brain for example, after a stroke, head injury or brain tumor.[1][2][3][4]

Introduction[edit | edit source]

As mentioned above aphasia is a condition resulting from damage to areas of the brain responsible for language, which for most people is located in the left hemisphere of the brain[5]. The condition presents as an impairment to comprehension or formulation of language and is often caused by diseases and disorders affecting the brain, with cerebrovascular accident being the most common cause[6].

[7]

Anatomy[edit | edit source]

Areas of the brain responsible for language:

  • Werncike's area
  • Broca's area
  • Arcuate fasciculus

The Wernicke's area is located in the temporal lobe and is responsible for processing visual and auditory information. It is the center for comprehension and planning of words. Broca's area on the other hand is located in the frontal lobe of the brain. It is responsible for motor execution of speech and sentence formation. While the arcuate fasciculus is the neural connection between both areas[8].

Symptoms of aphasia[edit | edit source]

Causes of aphasia[edit | edit source]

Aphasia can occur from a number of brain injuries and conditions such as:

Types of Aphasia[edit | edit source]

Aphasia can be broadly classified as either fluent or non-fluent.[9]

  1. Non-Fluent aphasia includes:
    • Broca's
    • Transcortical motor
    • Mixed transcortical
    • Global
  2. Fluent aphasia types are:
    • Wernicke's
    • Transcortical sensory
    • Conduction
    • Anomic[6]

The most common types of aphasia include:

  • Broca's aphasia.
    • Occurs from damage to the frontal lobe.
    • Patients may understand what is being said them, know what response to give but may often reply with short phrases with so much effort.
    • Patients may become frustrated from their difficulty in communicating clearly making some sliding into depression.
    • May often present with right hemiparesis/hemiplegia as the frontal lobe is also important for motor movements.
    • Also referred to as expressive aphasia.
  • Wernicke's aphasia
    • Occurs from damage to Brodmann area 22 of the temporal lobe also known as Wernicke's area
    • Is characterised by patients composing and speaking long, complete sentences that have no meaning. They may even formulate non-existent new words to express themselves.
    • They experience difficulty in understanding speech.
    • These patients are often unaware of their speaking blunders.
    • It is also known as receptive aphasia.
  • Global Aphasia
    • May have trouble understanding simple words and sentences.
    • May be limited in their ability to speak and comprehend language.[5]

Other forms of aphasia are:[6]

  • Conduction Aphasia is caused by lesion located in the arcuate fasciculus. Patients with this type of aphasia experience difficulties with or are unable to repeat words spoken to them. They realise the errors they make and endeavour to correct them.
  • Transcortical Sensory Aphasia is caused by lesions around but not affecting the Wernicke's area. Patients may be able to repeat speech fluently but have difficulties with comprehension.
  • Transcortical Motor Aphasia is from lesions around but that do not affect the Broca's area. Patients have a tendency to remain silent and may repeat one to two words. They may also be able to repeat long complex phrases although their speech may not be fluent.
  • Mixed Transcortical Aphasia results from lesions around the language areas of the brain but that do not affect them. Patients in this category have severe speaking and comprehension impairment but can repeat long, complex sentences.
  • Anomia is the mildest form of aphasia and is from damage to angular gyrus. It is characterised by patients having difficulties with finding words.

Differential Diagnoses[edit | edit source]

  • Dysphonia
  • Dysarthria
  • Cognitive communication disorder
  • Altered mental status from encephalopathy[6]

Relevance to Physiotherapy[edit | edit source]

Physiotherapists get to manage patients with neurological conditions that may and often lead to aphasia. It is important to be knowledgeable about the condition and its types to aid appropriate referral if/when detected by the physiotherapist in the course of patient care, and also to optimise interaction with patients.

References[edit | edit source]

  1. NHS choices. NHS; 2021 March 23. Available from: https://www.nhs.uk/conditions/aphasia/
  2. Damasio AR. Aphasia. New England Journal of Medicine. 1992 Feb 20;326(8):531-9.
  3. Berthier ML. Poststroke aphasia. Drugs & aging. 2005 Feb;22(2):163-82.
  4. Geschwind N. Aphasia. New England Journal of Medicine. 1971 Mar 25;284(12):654-6.
  5. 5.0 5.1 5.2 National Institute on Deafness and Other Communication Disorders, Aphasia. Available from: https://www.nidcd.nih.gov/health/aphasia (accessed 28 July, 2021)
  6. 6.0 6.1 6.2 6.3 Le H, Lui MY. Aphasia. StatPearls [Internet]. 2021 Jun 13.
  7. TED-Ed. Aphasia: The disorder that makes you lose your words - Susan Wortman-Jutt. Available from: http://www.youtu.be/-GsVhbmecJA [last accessed 29/7/2021]
  8. Ochfeld E, Newhart M, Molitoris J, Leigh R, Cloutman L, Davis C, Crinion J, Hillis AE. Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke. Stroke. 2010 Feb 1;41(2):325-30.
  9. Aphasia. NIH. Available from https://www.nidcd.nih.gov/health/aphasia [last accessed 11/11/2021]