The Effectiveness of Manual Therapies on the Thoracic Spine
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Introduction[edit | edit source]
There is limited epidemiological literature surrounding the thoracic spine. This was made evident when a systematic review found that thoracic spinal pain has prevalence data which ranges greatly from 4.0–72.0% between different studies. It has often been said that the thoracic spine is the ‘Cinderella region’ of the spine but it may be viewed as a ‘silent contributor’ to clinical presentations of shoulder and neck pain. Therefore, understanding the effectiveness of manual therapy on the thoracic spine may improve patient’s symptoms when suffering from thoracic and/or referred pain.
There are various common disorders in the thoracic spine, the most common;
- thoracic disc herniations,
- minor intervertebral derangement theory of Maigne,
- thoracic pain of lower cervical origin,
- thoracic pain of thoracic origin, thoracic hypo-mobility syndromes,
- upper thoracic spinal syndromes, mid-thoracic and costovertebral disorders,
- lower thoracic spine and thoracolumbar junction dysfunction,
- thoracic derangement theory of McKenzie,
- thoracic hyper-mobility problems,
- rib conditions,
- senile kyphosis,
- postural disorders.
Manual therapy techniques such as joint mobilisation, manipulation and soft tissue mobilisation can be used in order to improve patient symptoms.
Manual Therapy Definition[edit | edit source]
The International Federation of Orthopaedic Manipulative Physical Therapists (http://www.ifompt.org) defines manual therapy techniques as:
"Any hands on treatment provided by the Physiotherapist; including joint mobilisation, manipulation or soft tissue therapy. With the aim to improve tissue extensibility; increase range of motion of the joint complex; mobilise or manipulate soft tissues and joints; induce relaxation; change muscle function; modulate pain; and reduce soft tissue swelling, inflammation or movement restriction."
Clinically Relevant Anatomy- Thorax[edit | edit source]
- It is the longest portion of the spine, connecting to the Cervical Spine above and the Lumbar Spine below
- It comprises of 12 Vertebrae (T1-T12)
- The vertebrae bodies have a similar structure to that of the cervical spine.
- The spinous process increase in size the further down the thoracic spine.
- Each vertebrae sits above and below a IVD. 
- T1-T11 articulate with the ribs to provide stability to the rib cage
Mobility of the Thoracic Spine[edit | edit source]
- Least mobile portion of the spine
- T1-T8 = reduced flexion and extension, increased axial rotation
- T9-T12 = increased flexion and extension, reduced axial rotation. 
Contraindications to Manual Therapy[edit | edit source]
The contraindications to Manual Therapy are split into Absolute contraindications and precautions. If a patient were to present with any of the absolute contraindications they must not be treated using manual therapies and referred on as appropriate. If any of the precautions present then a patient must be treated with care and their symptoms monitored carefully throughout and after the treatment. The contraindications for each manual therapy under the relevant modalites.
Precautions for Manual Therapy[edit | edit source]
- OA (how advanced and signs and symptoms)
- Neurological signs and symptoms
- Cognitive Deficit
- SIN Factor
- Previous Spinal Surgery
- Auto-immune Disorders
- Chronic Fatigue
Mobilisations[edit | edit source]
They are often used in Physiotherapy management in order to produce mechanical and neurophysiological effects. It has been theorised by many authors that this is achieved when the sympathetic nervous system is excited following mobilisations, and thus the pain threshold increases. There have been several RCT's surrounding this area of interest so a systematic review was written by Kingston et al (2014) on the topic and found that each study did demonstrate a sympo-excitatory response. Therefore following an acute injury, or where a patient is suffering from painful inflammation of the target area, it would be useful to treat them centrally, using mobilisations, away from the target area. This can be performed at any level of the spine, including the thoracic spine.
Pulmonary Function[edit | edit source]
Recent evidence has been published acknowledging the benefits of thoracic mobilisations on pulmonary function in patients. When combined with self stretching exercises on the pec minor and major muscle group along with the trapezius muscles, thoracic joint mobilisations have been shown to be statistically superior in improving FEV1, and PEF than self stretching alone. However, self stretching and thoracic mobilisations was statistically greater in improving FVC than thoracic joint mobilisations alone.
Mobilisations are not limited to use in the solely MSK setting, they can also be used with patients who suffer neurological deficit. Stroke patients often suffer with limited thoracic movement and impaired coughing ability leading to further respiratory complications. Combined weekly thoracic and cervical joint mobilisations ( with movement) along with 30 minutes of exercise, 15 minutes of ergometer training and 15 minutes of functional electrical stimulation a week, has been shown to improve FEV1, FVC and coughing function greater than exercise, ergometer training and electrical stimulation alone. To add to this, mobilisation of the thoracic spine promotes mobility and improves the respiratory function in patients with Ankylosing Spondylitis (p<0.05).
Shoulder Pain[edit | edit source]
Shoulder pain is a very prevalent condition with 1 in 3 people expected to suffer from it in their lifetimes. As most clinical tests lack specificity, there is no gold standard clinical test for shoulder pathologies so clinical trials lead to the use of the term 'non-specific shoulder pain'. Due to the anatomical position of the shoulder girdle and thoracic spine. Treatment on the thoracic spine can treat pain in the shoulder. Thoracic joint mobilisations have been found to statistically accelerate recovery and reduction of pain and disability in patients with non-specific pain between 12 and 52 weeks.
To further this, Thoracic Mulligans Concept SNAGs may influence short term pain levels and shoulder mobility in patients with secondary impingement syndrome. This is where SNAGs are defined as a sustained natural apophyseal glide.
Neck Pain[edit | edit source]
Decreased mobility of the thoracic spine has become significantly related to neck pain because of biomechanical links between the thoracic and cervical spine.
Inclusion of thoracic mobilisation with craniocervical flexor exercise in patients with chronic neck pain versus exercises alone showed greater improvements in VAS pain, muscular endurance and the neck disability index.
Thoracic mobilisations on non-specific neck pain found Maitland mobilisation along with the conventional treatment proved to be more effective in improving Neck Disability Index (NDI) and Numeric Pain Rating Scale scores in patients with nonspecific neck pain than Mulligan mobilisation along with the conventional treatment.
The effectiveness between manipulation (thrust manipulation) and mobilsations directed at the thoracic spine in patients with neck pain found that patients in the manipulation group experienced greater reductions in disability and pain compared to the mobilisations group . Subjects receiving manipulation experienced greater reductions in disability, with a between-group difference of 10%, and pain, with a between-group difference of 2% .
Spondylolisthesis & Lower Back Pain[edit | edit source]
Segmental instability due to lumbar spondylolisthesis can be a cause of chronic low back pain. Hypomobility of the spine can result in compensatory segmental hypermobility of the segment above or below restricted vertebrae. A study investigated the effects of mobilisation therapy of the hypomobile upper thoracic spine along with conventional exercises.
The study concludes that lower back pain due to spondylolisthesis may be benefited by mobilisation of the thoracic spine along with stretching of short hip flexors, piriformis, lumbar flexion range of motion exercises, core strengthening exercises, etc.
Ankylosing Spondylitis[edit | edit source]
A recent study investigated the effects of manual mobilisation on the mobility of the thoracic spine in patients with Ankylosing Spondylitis (Axial Spondyloarthritis). They found that range of movement of the thoracic spine (Ott’s sign) increased significantly within the group of manually mobilised patients compared to baseline at each of the follow-up visits, whereas no significant change on thoracic spine mobility could be detected in the control group at each of the follow-ups.
By comparing both groups, a significantly improved mobility of the manually mobilised patients at discharge and one month later was observed. There was no difference between the two groups at baseline and after 3 months. An impact on pain reduction (VAS) was not achieved in the control group, in the manually mobilised group pain reduction became obvious compared to baseline. Parameters of the respiratory function improved significantly during therapy with manual mobilisation.
Contraindications for Spinal Joint Mobilisation[edit | edit source]
- Inflammatin Sero-positive arthropathy Rheumatoid ===
Blood Vessel Patency
- Aortic aneurysm
- Vertebral arterial dysfunction
- Frail skin
- Peripheral vascular disease
Manipulations[edit | edit source]
"A manual therapy technique comprising a continuum of skilled passive movements to the joint complex that are applied at varying speeds and amplitudes, that may include a small-amplitude/ high velocity therapeutic movement with the intent to restore optimal motion, function, and/ or to reduce pain." 
Grades: Maitland Joint Mobilisation Scale [edit | edit source]
Grade I - Small amplitude rhythmic oscillating mobilization in early range of movement
Grade II - Large amplitude rhythmic oscillating mobilization in midrange of movement
Grade III - Large amplitude rhythmic oscillating mobilization to point of limitation in range of movement
Grade IV - Small amplitude rhythmic oscillating mobilization at endrange of movement
Grade V (Thrust Manipulation) - Small amplitude, quick thrust at endrange of movement
Cervicogenic Headaches [edit | edit source]
Evidence surrounding manipulations in the management of cervicogenic headaches is constantly evolving, with current evidence suggesting that thoracic manipulations should be used as a longterm treatment plan. A systematic review by Posadzki and Ernst, (2012), including 5 RCT's showed that no significant differences between the manipulation and control groups were observed in any of the 3 outcome measures. However, by week 7, each group experienced significant reductions in mean daily headache hours and mean number of analgesics per day. These changes were maintained through the observation period. From this, it can be seen that thoracic manipulations for the treatment of Cercicogenic headaches is encouraging, with long term effects, but not conclusive.
Research also suggests that manipulations alongside soft tissue therapy, re-education and muscle strengthening exercises showed a 50% decrease in tension headache length. Therefore the specific effects of manipulations alone are not clear, but a positive effect can be seen through using them as a treatment option.
Neck Pain[edit | edit source]
Neck pain is prevalent in the general population, often leading to physical impairments and disability; with the 2016 Global Burden of Disease, Injuries, and Risk Factors ranking neck pain 11th overall in global cause of disability-adjusted life years. Conservative treatment of neck pain, often includes various interventions, such as education, modalities, therapeutic exercises, mobilisation and manipulation. A 2019 systematic review and meta-analysis compared thoracic and cervical mobilisations to thoracic manipulations using the outcome measures of pain (VAS Scale) and disability (Neck Disability Index). The results of this systematic review conveyed that thoracic manipulations are more effective than cervical and thoracic mobilisations in reducing perceived pain and disability on a short term basis. These results are consistent with the findings of previous reviews conducted by Huisman et al and Young et al, who also concluded that thoracic manipulations have a short-term clinical benefit when compared to modalities, thoracic manipulations and exercise.
Adhesive Capsulitis[edit | edit source]
Adhesive capsulitis (AC) is a common and disabling shoulder condition which has no clear consensus as to the best treatment approach. Recently there has been emerging evidence that mobilisations directed at the thoracic spine may be beneficial for patients with shoulder pain.
In many patients with AC pain, it is noted that they have thoracic spine mobility and ROM deficits. Therefore a case report was created where treatment consisted of both low-velocity mid-range (grade III and IV), and high-velocity end-range (grade V), posterior to anterior forces directed at the mid and upper thoracic spine. The high-velocity techniques were repeated 1–2 times at each of those levels, without attempting to identify specific segmental levels due to research by Beffa et al, (2004) suggesting an inability to localize treatment.
Shoulder flexion ROM was measured both immediately before and after the thoracic manipulations to be used as an outcome measure. Prior to treatment active shoulder flexion ROM was 110°, and immediately following treatment it had improved to 135°. This represents an immediate post-treatment improvement of 25° which greatly exceeds the 10° difference required to be confident a real change has occurred.
The same treatment regimen for the thoracic spine was repeated over the next three visits (visits 12–14) in addition to the previously established plan of active/passive ROM and joint mobilizations of the glenohumeral joint. At each visit, the patient continued to report decreased pain and improved function. After only four visits of thoracic manipulations, substantial improvements were noted. The patient continued to make progress once it was determined the thoracic spine deficits had been addressed and thoracic manipulations were discontinued.
This case suggests that thoracic manipulations may be a useful treatment for patients with AC. Though this is only a case report, it is the first to look at using thoracic manipulations for AC specifically, and it adds to the emerging evidence that manual therapy directed at the thoracic spine should be considered for patients with shoulder pain.
Contraindications for Spinal Manipulations[edit | edit source]
- Vertebral Basilar Insufficiency
- Atherosclerosis of major vessels
- Cervical Arterial Dysfunction
- Bacterial Infection
- Joint instability
- Severe strains/sprains
- Unstable Spondylolisthesis
- Rheumatoid Arthritis
- Ankylosing Spondylitis
- Psoriatic Arthritis
- Osteoarthitis (unstable stage)
- Pain intolerance
- No cognitive capacity
- Clotting Disorders
- Sacral nerve root involvement from disc protrusion
- Disc lesions
- Space Occupying lesion
- Progressive Neurological Disorders
- Cauda Equina
Soft Tissue (STT)[edit | edit source]
Soft tissue therapy is a mechanical, hands-on type of therapy that stretches, kneads, or presses the soft tissue (muscles, fascia, ligaments, tendons). The technique is normally applied with mechanical forces, administered through the hands, elbows, or mechanical devices (e.g. Graston technique / instrument assisted soft tissue therapy). STT can be categorised into several classifications, all of which are thought to serve a different purpose, these include:
- Massage Therapy
- Trigger point therapy
- Myofascial release
- Instrument assisted soft tissue therapy
Massage Therapy[edit | edit source]
Massage is widely used as a therapeutic technique to help improve outcomes in a range of conditions including: skin conditions (surgical sores/scars, burns scars, cleft lip scars), pain syndromes (including fibromyalgia and arthritis), hypertension, autoimmune conditions (including asthma and multiple sclerosis), immune disorders (including HIV/AIDS), cancer patients and degenerative conditions common in ageing populations (including Parkinson's and Dementia). A Cochrane Review looking at the effects of massage therapy with and without aromatherapy showed inconclusive results in a population of cancer patients due to many of the included papers having high risk of biases. .
Furthermore, another Cochrane Review in 2015, focussing on massage as a treatment for low back pain concluded that the modality is effective at decreasing pain and increasing function, but only in short-term follow up. Massage therapy is most effective when used in conjunction with other treatment modalities, such as mobs/manipulations and exercise, for improvement in long-term outcomes. It should be noted that massage is not a standardised treatment however, and there are many different variables which may affect the potential of the treatment modality. These could include the massage technique used (including the frequency, duration and number of treatment sessions), intensity of pressure applied, experience of the therapist, stress levels of the individual, and heterogeneity of participants in addition to other confounding variables e.g. co-interventions. Additionally, to the best knowledge, there is no evidence (Cochrane Review) available on the effectiveness of massage on the Thoracic spine. Outcomes related to the Thoracic spine may show better results, and until researched rigorously, this remains unclear.
Types of Massage[edit | edit source]
Generally, there are 6 types of massage commonly used, these include:
Swedish Massage[edit | edit source]
This is commonly termed 'relaxation' massage as the aim of the massage is to bring patients to a state of ease and relaxation. Swedish massage is commonly made up of several techniques, these are listed below:
- Effleurage: Long gliding strokes with the hands (palms, thumbs and/or fingers).
- Petrissage: Global kneading motion with the hands (palms, thumbs and/or fingers).
- Friction: Circular pressures with the palms of hands, thumbs and/or fingers.
- Vibration: Oscillatory movements that shake or vibrate the body.
- Percussion: Brisk hacking or tapping.
- Passive and active movements: Bending and stretching.
Hot Stone Massage:[edit | edit source]
This technique is often used in combination with other massage therapy techniques, and involves the use of hot stones heated to over 100 degree Fahrenheit on the patient's back and shoulders. It is believed to help improve circulation and promotes relaxation, however research in the field is somewhat limited to validate its efficacy.
Thai Massage[edit | edit source]
This massage technique is considered to be one of the most energising techniques you can get. It involves the massage therapist passively moving and stretching the patient into various yoga-type positions, and will often pull the patients toes, ears and fingers. In addition to this, the therapist will also attempt to crack knuckles and walk along the spine - effectively producing a joint manipulation. It has been suggested that this technique can 'better your posture' and improve breathing, prevent illness and slow the ageing process, however research does not present any evidence to validate these claims. Rather than the benefits previously described, systematic review research including 6 RCTs showed benefits for reducing chronic pain patients perceived pain, varying from 25% to 80%, and is also associated with improvements in disability, perceived muscle tension, flexibility and anxiety.
Reflexology[edit | edit source]
Reflexology is a technique performed using the thumb and forefingers to apply pressure to specific areas on the feet. These areas have been claimed to correspond to internal organs glands and varying body parts. A 2008 Systematic Review concluded that there was no evidence for any specific effect of reflexology in any conditions; out of 12 outcome variables examined, only one showed a statistically significant effect, this was for the treatment of urinary symptoms associated with multiple sclerosis. The review concluded that the provision of reflexology should not be routine, and is therefore not recommended for use.
Deep Tissue Massage[edit | edit source]
Deep Tissue Massage (DTM) is generally performed for muscles that have been strained related to chronic pain, 'postural issues', or repetetive strains and stresses. The therapist targets deep layers of muscles and connective tissues by repeated, intense short strokes. This method of massage therapy is often related to myofascial trigger points due to theorised increase tension within the soft tissues. Two Cochrane reviews have looked at the effects of DTM in the treatment of lateral elbow and knee tendinopathy[, results were inconclusive however, and the authors concluded that there was insufficient evidence to determine the effectiveness of DTM. In contrast, Joseph et al. (2012), evaluated the effects of DTM in the treatment of an injured tendon; 9 studies evaluated the effect of DTM in the shoulder, lateral elbow, thigh and ankle. PEDro scores ranged from 4-7, and the review concluded that there was evidence to support the use of DTM in the treatment of tendinopathy, however, not as a stand alone treatment.
Massage Therapy Theories[edit | edit source]
Melzack and Wall (1965) Gate Control Theory[edit | edit source]
- This theory suggests that the amount of mechanical pressure provided during a massage is sufficient enough to create a large enough stimulus that interferes with transmission of pain stimuli to the brain, therefore reducing the perceived levels of pain an individual will experience.
- The effects are only short-lived however, and meta-analytical data suggests there is no significant immediate effect on pain following a massage. However, it is to note that studies included in the M-A had varying treatment times (15 minutes – 1 hour), so it may be plausible that the treatment time was not sufficient enough to elicit an effect on the spinal pain gate. In addition, modalities used to quantify pain varied, perhaps reducing the internal validity of the study.
- The effect size for immediate pain score following massage was 0.28, non-significant, but still reflects some improvement within pain ratings across the studies.
- The notion of MT having an analgesic effect consistent with gate control theory, appears in the literature more than any other theory pertaining to MT.
Promotion of Parasympathetic Activity[edit | edit source]
- Another theory suggests that the positive responses seen with massage therapy is attributable to a shift in autonomic activity; from a state of arousal (sympathetic) to a state of relaxation (parasympathetic).
- The pressure applied during massage is thought to stimulate vagal nerve activity; the vagus nerve is the tenth cranial nerve (CN X), and interfaces with parasympathetic control of the cardiovascular systems, and the digestive tract; the parasympathetic response reduces heart rate, blood pressure, and respiration rate.
- Opposingly, no significant difference in HR, blood pressure and skin temperature following a 30-minute back massage has been reported. This study did however report a significant decrease in respiration rates. This may support a unique subject response pattern or may indicate that some parasympathetic parameters are activated during massage. However, cautious interpretation of results should be taken due to lack of sample size and no use of a control group within the study.
Influence on body chemistry[edit | edit source]
- A few studies have linked massage therapy with the release of serotonin , which is thought to inhibit the transmission of afferent noxious nerve signals to the brain
- Other research suggests that the application of massage through pressure stimulates the release of endorphins into the bloodstream ; these mechanisms may provide pain relief or feelings of well-being by influencing the body chemistry.
Mechanical Effects:[edit | edit source]
- Some published data may indicate that massage therapy can speed healing and reduce pain through mechanical means (pain gaiting). The mechanical pressure and manipulation implemented onto the tissues may break down subcutaneous adhesions and reduce potential of fibrosis occurring.
- In addition, mechanical pressure applied to superficial and deep tissues can promote circulation (venous return and peripheral circulation) and lymphatic drainage. These processes are believed to lead to a reduction in pain associated with injury and exercise .
Promotion and Restoration of Sleep:[edit | edit source]
- Individuals who have poor quality of sleep may experience changes in their body chemical balances, of which lead to heightened perceptions of pain.
- When sleep quality is poor, levels of neurotransmitter substance P increase, and levels of somatostatin decrease, both of which have been shown to influence pain .
- The use of massage therapy can help to promote ‘deeper’, less disturbed sleep in a sample of fibromyalgia patients – patients experienced a reduction in pain rating during the course of the treatment.; This may suggest that massage therapy can help reduce pain indirectly, through improve the quality of restorative sleep.
- Pittsburgh Sleep Quality Index (PSQI), a commonly used tool to measure sleep quality, was used as an outcome in a population of cancer patient care givers. The care-givers were provided with massage treatment (15 minutes daily, 7 days) across the lumbar / thoracic spine region. Significant improvements in the quality of sleep within this population was observed (rate of poor sleep decreased by 13.7%; p<0.01) .
Myofascial Release[edit | edit source]
Myofascial Release (MFR) is a technique used to help relieve tension build-up within the body's fascia network. Fascia is made up of collagen and is viscoelastic in nature; it allows the body to retain normal shape, restrict mechanical stresses, and holds organs in place. On a molecular level, fascia is made up of:
- Collagen: Protein that has a large tensile strength, and contributes to the strength and guard over tension.
- Elastin: Protein that is 'rubber like', and located where elasticity would be required
- Polysaccharide gel: Made up of two components: Hyaluronic acid - lubricates the proteins within the fascia ; Proteoglycans - forms a gel of ground substance, which act as a shock absorbant.
Fascia is considered by most to be a source of nociceptive pain, also known as myofascial pain, within a number of musculoskeletal disorders, including: 'non-specific' back pain, plantar fasciitis, and lateral epicondylitis.
On the Thoracic spine, MFR has been shown to be effective in increasing ROM and pain pressure threshold. The technique involved in releasing the fascia includes a passive stretch onto superficial fibres, this is thought to stimulate the fascia, leading to a change in viscosity and density, transforming it into a more fluid state.  This results in stimulation of Ruffini corpuscles, mechanosensitive nerves, which are associated with a decreased activity of the sympathetic portion of the autonomic nervous system - fascia has a high density of free nerve endings that belong to the sympathetic nervous system. Similarly, the stimulation of sensory mechanoreceptors activates the anterior lobe of the hypothalamus, which in turn induces a global overall decrease in sympathetic tone and emotional arousal, as well as decreases in local tissue viscosity.
Contraindications for Massage Therapy:[edit | edit source]
- Varicose Veins
- Anti-coagulation disease
- Heart Failure
- Open wound
- Skin disease
- Recent Scar
- Inflammed tissue
- Recent Fracture
- Inflammatory Arthritis
- Infected tissue
- Contagious infection
Conclusion[edit | edit source]
Thoracic mobilisations, manipulations and soft tissue therapies all have a place within rehabilitation and treatment; ranging from musculoskeletal disorders, to respiratory conditions and psychological health. However, the benefits primarily seen are often short-term and non-specific resulting in patients requiring recurrent treatment.
From the research and literature it can be deduced that all three manual therapy techniques reduce perceived pain, muscle tension and disability  in the short term, providing the patient with instant relief. This instant effect often allows the therapist to assess and treat the root cause due to the patient’s reduced pain and increased mobility.
Evidence suggest that all three techniques should be provided alongside other modalities such as exercise in order to produce a long-term reduction in symptoms and reduce the chance of recurrence. Even so manual therapy techniques are essential within physiotherapy and the positive outcomes they provide are crucial to a patient-centred approach and treatment.
References[edit | edit source]
- Palastanga, N. and Field, D. (2014). Anatomy and Human Movement. Kent: Elsevier Science.
- Edmond S. Joint Mobilization/Manipulation - E-Book. 3rd ed. Elsevier Health Sciences.; 2016.
- Kingston L, Claydon L, Tumilty S. The effects of spinal mobilizations on the sympathetic nervous system: A systematic review. Manual Therapy. 2014;19(4):281-287.
- Hwangbo P, Hwangbo G, Park J, Lee S. The Effect of Thoracic Joint Mobilization and Self-stretching Exercise on Pulmonary Functions of Patients with Chronic Neck Pain. Journal of Physical Therapy Science. 2014;26(11):1783-1786.
- Ogiwara S, Ogura K. Antero-Posterior Excursion of the Hemithorax in Hemiplegia. Journal of Physical Therapy Science. 2001;13(1):11-15.
- Gauld L, Boynton A. Relationship between peak cough flow and spirometry in Duchenne muscular dystrophy. Pediatric Pulmonology. 2005;39(5):457-460.
- 6. Jang S, Bang H. Effect of thoracic and cervical joint mobilization on pulmonary function in stroke patients. Journal of Physical Therapy Science. 2016;28(1):257-260.
- Meier F, Sperling M, Tarner I, Müller-Ladner U, Lange U. THU0354 The Effects of Manual Mobilisation on the Mobility of the Thoracic Spine in Patients with Ankylosing Spondylitis. Annals of the Rheumatic Diseases. 2013;72(Suppl 3):A284.2-A284.
- van der Heijden G. Shoulder disorders: a state-of-the-art review. Best Practice & Research Clinical Rheumatology. 1999;13(2):287-309.
- Lewis J. Rotator cuff tendinopathy/subacromial impingement syndrome: is it time for a new method of assessment?. British Journal of Sports Medicine. 2009;43(4):259-264.
- Dickens V, Williams J, Bhamra M. Role of physiotherapy in the treatment of subacromial impingement syndrome: a prospective study. Physiotherapy. 2005;91(3):159-164.
- Peek A, Miller C, Heneghan N. Thoracic manual therapy in the management of non-specific shoulder pain: a systematic review. Journal of Manual & Manipulative Therapy. 2015;23(4):176-187.
- Andrews D, Odland-Wolf K, May J, Baker R, Nasypany A. THE UTILIZATION OF MULLIGAN CONCEPT THORACIC SUSTAINED NATURAL APOPHYSEAL GLIDES ON PATIENTS CLASSIFIED WITH SECONDARY IMPINGEMENT SYNDROME: A MULTI-SITE CASE SERIES. International Journal of Sports Physical Therapy. 2018;13(1):121-130.
- Hing W, Hall T, Rivett D, Vicenzino B, Mulligan B. The Mulligan Concept of Manual Therapy - eBook: Textbook of Techniques. Chatswood: Elsevier; 2015.
- Ko T, Jeong U, Lee K. Effects of the Inclusion Thoracic Mobilization into Cranio-Cervical Flexor Exercise in Patients with Chronic Neck Pain. Journal of Physical Therapy Science. 2010;22(1):87-91.
- Inderpreet K, Arunmozhi R, Umer A. EFFECT OF MAITLAND VS MULLIGAN MOBILISATION TECHNIQUE ON UPPER THORACIC SPINE IN PATIENTS WITH NON-SPECIFIC NECK PAIN - A COMPARATIVE STUDY. International Journal of Physiotherapy and Research. 2013;1(5):214-18.
- Cleland J, Glynn P, Whitman J, Eberhart S, MacDonald C, Childs J. Short-Term Effects of Thrust Versus Nonthrust Mobilization/Manipulation Directed at the Thoracic Spine in Patients With Neck Pain: A Randomized Clinical Trial. Physical Therapy. 2007;87(4):431-440.
- Mohanty P, Pattnaik M. Mobilisation of the thoracic spine in the management of spondylolisthesis. Journal of Bodywork and Movement Therapies. 2016;20(3):598-603.
- Mintken P, Derosa C, Little T, Smith B. A Model for Standardizing Manipulation Terminology in Physical Therapy Practice. Journal of Orthopaedic & Sports Physical Therapy. 2008;38(3):A1-A6.
- Rao R, Balthillaya G, Prabhu A, Kamath A. Immediate effects of Maitland mobilization versus Mulligan Mobilization with Movement in Osteoarthritis knee- A Randomized Crossover trial. Journal of Bodywork and Movement Therapies. 2018;22(3):572-579.
- Posadzki P, Ernst E. Spinal manipulations for tension-type headaches: A systematic review of randomized controlled trials. Complementary Therapies in Medicine. 2012;20(4):232-239.
- Bove G, Nilsson N. Spinal Manipulation in the Treatment of Episodic Tension-Type Headache. JAMA. 1998;280(18):1576.
- Castien R, van der Windt D, Grooten A, Dekker J. Effectiveness of manual therapy for chronic tension-type headache: A pragmatic, randomised, clinical trial. Cephalalgia. 2010;31(2):133-143.
- Mokdad A, Ballestros K, Echko M, Glenn S, Olsen H, Mullany E et al. The State of US Health, 1990-2016. JAMA. 2018;319(14):1444.
- Masaracchio M, Kirker K, States R, Hanney W, Liu X, Kolber M. Thoracic spine manipulation for the management of mechanical neck pain: A systematic review and meta-analysis. PLOS ONE. 2019;14(2):e0211877.
- Masaracchio M, Kirker K, States R, Hanney W, Liu X, Kolber M. Thoracic spine manipulation for the management of mechanical neck pain: A systematic review and meta-analysis. PLOS ONE. 2019;14(2):e0211877.
- Huisman P, Speksnijder C, de Wijer A. The effect of thoracic spine manipulation on pain and disability in patients with non-specific neck pain: a systematic review. Disability and Rehabilitation. 2013;35(20):1677-1685.
- Young J, Walker D, Snyder S, Daly K. Thoracic manipulation versus mobilization in patients with mechanical neck pain: a systematic review. Journal of Manual & Manipulative Therapy. 2013;22(3):141-153.
- Mintken P, Cleland J, Carpenter K, Bieniek M, Keirns M, Whitman J. Some Factors Predict Successful Short-Term Outcomes in Individuals With Shoulder Pain Receiving Cervicothoracic Manipulation: A Single-Arm Trial. Physical Therapy. 2010;90(1):26-42.
- Beffa R, Mathews R. Does the adjustment cavitate the targeted joint? an investigation into the location of cavitation sounds. Journal of Manipulative and Physiological Therapeutics. 2004;27(2):118-122.
- Ross J, Bereznick D, McGill S. Determining Cavitation Location During Lumbar and Thoracic Spinal Manipulation. Spine. 2004;29(13):1452-1457.
- Mullaney M, McHugh M, Johnson C, Tyler T. Reliability of shoulder range of motion comparing a goniometer to a digital level. Physiotherapy Theory and Practice. 2010;26(5):327-333.
- McCormack J. Use of thoracic spine manipulation in the treatment of adhesive capsulitis: a case report. Journal of Manual & Manipulative Therapy. 2012;20(1):28-34.
- Gatterman M. Standards of practice relative to complications of and contraindications to spinal manipulative therapy. The Journal of the CCA. 1991;35(4):67-68.
- Shin T.M. & Bordeaux J.S. (2013). "The role of massage in scar management: a literature review." Dermatologic Surgery. 2013;38(3):414-23.
- Cho Y.S., Jeon J.H., Hong A., Yang H.T., Yim H., Cho Y.S., Kim D.H., Hur J., Kim J.H., Chun W., Lee B.C. and Seo C.H. (2014). "The effect of burn rehabilitation massage therapy on hypertrophic scar after burn: a randomized controlled trial." Burns. Volume 40(8). Pg. 1513-20.
- McKay E. "Assessing the effectiveness of massage therapy for bilateral cleft lip reconstruction scars." International Journal of Therapeutic Massage and Bodywork. 2014;7(2):3-9.
- Field T. "Massage therapy research review." Complementary Therapies in Clinical Practice. 2014;20(4):224-9.
- Cortés Godoy V., Gallego Izquierdo T., Lázaro Navas I. and Pecos Martín D. "Effectiveness of massage therapy as co-adjuvant treatment to exercise in osteoarthritis of the knee: a randomized control trial." Journal of Back and Musculoskeletal Rehabilitation. 2014:27(4);521-9.
- Xiong X.J., Li S.J. and Zhang Y.Q. (2015). "Massage therapy for essential hypertension: a systematic review." Journal of Human Hypertension. 2015;29(3):143-51.
- Fattah M.A. & Hamdy B. "Pulmonary functions of children with asthma improve following massage therapy." Journal of Alternative Complementary Medicine. 2011;17(11):1065-8.
- Finch P. & Bessonnette S. "A pragmatic investigation into the effects of massage therapy on the self efficacy of multiple sclerosis clients." Journal of Bodywork and Movement Therapies. 2014;18(1):11-16.
- Perez E.M., Carrara H., Bourne L., Berg A., Swanevelder S. & Hendricks M.K. "Massage therapy improves the development of HIV-exposed infants living in a low socio-economic, peri-urban community of South Africa." Infant Behaviour and Development. 2015;38:135-46.
- Çelebioğlu A., Gürol A., Yildirim Z.K. & Büyükavci M. "Effects of massage therapy on pain and anxiety arising from intrathecal therapy or bone marrow aspiration in children with cancer." International Journal of Nursing Practice. 2015;21(6):797-804.
- Kashani F. & Kashani P. (2014). "The effect of massage therapy on the quality of sleep in breast cancer patients." Iranian Journal of Nursing and Midwifery Research. 2014;19(2):113-8.
- Donoyama N., Suoh S. & Ohkoshi N. "Effectiveness of Anma massage therapy in alleviating physical symptoms in outpatients with Parkinson's: a before-after study." Complementary Therapies in Clinical Practice. 2014;20(4):251-61.
- Rodríguez-Mansilla J., González-López-Arza M.V., Varela-Donoso E., Montanero-Fernández J., Jiménez-Palomares M. & Garrido-Ardila E.M. "Ear therapy and massage therapy in the elderly with dementia: a pilot study." Journal of Traditional Chinese Medicine. 2013;33(4):461-7.
- Field T. "Massage Therapy Research Review." Complementary Therapies in Clinical Practice. 2017;24: 19-31.
- Shin E.S., Seo K.H., Lee S.H., Jang J.E., Jung Y.M., Kim M.J. & Yeon J.Y. "Massage with or without aromatherapy for symptom relief in people with cancer." Cochrane Database of Systematic Reviews. 2016;6:CD009873.
- Furlan A.D., Giraldo M., Baskwill A., Irvin E. & Imamura M. "Massage for low-back pain". Cochrane Database for Systematic Reviews. 2015;9:CD001929.
- Keeratitanont K., Jensen M.P., Chatchawan U. & Auvichayapat P. "The efficacy of traditional Thai massage for the treatment of chronic pain: A systematic review." Complementary Therapies in Clinical Practice. 2015;21(1):26-32.
- Botting D. "Review of literature on the effectiveness of reflexology." Complementary Therapies in Nursing & Midwifery. 1997;3:123–130.
- Wang M.Y., Tsai P.S., Lee P.H., Chang W.Y. & Yang C.M. "The efficacy of reflexology: systematic review." Journal of Advanced Nursing. 2008;62(5):512-20.
- Brosseau L., Casimiro L., Milne S., Robinson V., Shea B., Tugwell P. & Wells G. (2002). "Deep transverse friction massage for treating tendinitis." Cochrane Database of Systematic Reviews. 2002;4:CD003528.
- Loew L.M., Brosseau L., Tugwell P., Wells G.A., Welch V., Shea B., Poitras S., De Angelis G. & Rahman P. "Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis." Cochrane Database Systematic Reviews. 2014;11:CD003528.
- Joseph M.F., Taft K., Moskwa M. & Denegar C.R. "Deep friction massage to treat tendinopathy: a systematic review of a classic treatment in the face of a new paradigm of understanding." Journal of Sport Rehabilitation. 2012;21:343-53.
- Melzack R. & Wall P.D. "Pain mechanisms: A new theory. Science. 1965;150:971–79.
- Moyer C.A., Rounds J. & Hannum J.W. "A Meta-Analysis of Massage Therapy Research." Psychological Bulletin. 2004;130(1):3-18.
- Field T.M. "Massage therapy effects. American Psychologist. 1998;53:1270-81.
- Zeitlin D., Keller S.E., Shiflett S.C., Schleifer S.J. & Barlett J.A. “Immunological Effects of Massage Therapy During Academic Stress.” Psychosomatic Medicine. 2000;62(1):83-84.
- Field T., Grizzle N., Scafidi F. & Schanberg S. "Massage and relaxation therapies’ effects on depressed adolescent mothers." Adolescence. 1996;31:903–11.
- Andersson S. & Lundeberg T. "Acupuncture— From empiricism to science: Functional background to acupuncture effects in pain and disease." Medical Hypotheses. 1995;45:271–281.
- Oumeish O.Y "The philosophical, cultural, and historical aspects of complementary, alternative, unconventional, and integrative medicine in the Old World. Archives of Dermatology. 1998;134:1373–86.
- Donnelly C.J. & Wilton J. "The effect of massage to scars on active range of motion and skin mobility." British Journal of Hand Therapy. 2002;7:5–11.
- Portillo-Soto A., Eberman L.E., Dernchak T.J. & Peebles C. “Comparison of Blood Flow Changes with Soft Tissue Mobilization and Massage Therapy.” Journal of Alternative and Complementary Medicine. 2014;20(12):932-36.
- Fritz S. Mosby’s fundamentals of therapeutic massage. St.Louis, MO: Mosby. 2000:475-478.
- Sayar K., Arikan M. & Yontem T. "Sleep Quality in Chronic Pain Patients." The Canadian Journal of Psychiatry. 2002;47(9):844–48.
- Sunshine W., Field T.M., Quintino O., Fierro K., Kuhn C., Burman I., et al. "Fibromyalgia benefits from massage therapy and transcutaneous electrical stimulation." Journal of Clinical Rheumatology. 1996;2:18–22.
- Pinar R. & Afsar F. "Back Massage to Decrease State Anxiety, Cortisol Level, Blood Pressure, Heart Rate and Increase Sleep Quality in Family Caregivers of Patients with Cancer: A Randomised Controlled Trial." Asian Pacific Journal of Cancer Prevention. 2015;16(18):8127-33.
- Laimi K., Mäkilä A., Bärlund E., Katajapuu N., Oksanen A., Seikkula V., Karppinen J. & Saltychev M. "Effectiveness of myofascial release in treatment of chronic musculoskeletal pain: a systematic review." Clinical Rehabilitation. 2018;32(4):440-50.
- Cathcart E., McSweeney T., Johnston R., Young H. & Edwards D.J. "Immediate biomechanical, systemic, and interoceptive effects of myofascial release on the thoracic spine: A randomised controlled trial." Journal of Bodywork and Movement Therapies. 2019;23(1):74-81.
- Schleip R. "Fascial plasticity - a new neurobiological explanation: Part 1." Journal of Bodywork and Movement Therapy. 2003;7(1):11-19.
- Rolf I. "Rolfing: the Integration of Human Structures." Dennis Landman, Santa Monica. 1977.
- Gellhorn E. "Principles of Autonomic-somatic Integration: Physiological Basis and Psychological and Clinical Implications." University of Minnesota Press, Minneapolis, MN 1967.
- Batavia M. Contraindications for therapeutic massage: do sources agree?. Journal of Bodywork and Movement Therapies. 2004;8(1):48-57.