Midcarpal Instability
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Definition/Description
mid-carpal Instability (MCI) or capitolunate instability is a condition affecting the wrist joint. It manifests as increased, abnormal mobility between the proximal and distal rows of the carpal bones. Common symptoms include persistent wrist pain, clicking, and limited functional capacity. The instability stems from lack of support of the proximal carpal row by ligamentous structures, as well as a disruption of normal joint forces between proximal and distal carpal rows. Palmar mid-carpal instability is more prevalent, but dorsal and extrinsic variants also exist.[1] It is named capitolunate instability as it mainly affects the joint between the capitate and the lunate the most two important wrist bones, which help the wrist to move smoothly.
Clinically Relevant Anatomy
The wrist is composed of eight carpal bones arranged in two rows. The proximal row includes the scaphoid, lunate, and triquetrum. The distal row consists of the trapezium, trapezoid, capitate, and hamate. Ligaments connect these bones, stabilising the joint.
Key to the stability of the mid-carpal joint is indirect by the arcuate ligament complex. This complex has two parts: an ulnar part, comprised of the triquetrohamatecapitate (THC) ligament, and a radial part that extends distally from the radioscaphocapitate ligament. Another important stabilising element for the proximal carpal row is the dorsal radiolunotriquetral ligament.
Epidemiology /Aetiology
mid-carpal instability is an uncommon condition but is more frequently seen in younger adults and athletes and may be associated with collagen disorders.[2][3] It often results from factors such as ligament laxity, trauma, or repetitive strain on the wrist. Two main forms, congenital and acquired.[3] The acquired form is commonly linked with wrist microtrauma or repetitive stress, and certain systemic conditions like rheumatoid arthritis may also contribute. The types of instability are:
Palmar mid-carpal Instability (PMC): This subtype is primarily caused by laxity in specific ligaments, namely the ulnar component of the arcuate ligament that connecting the triquetrum, hamate, and capitate and the dorsal radiolunotriquetral ligament/ dorsal radiocarpal (DRC). These ligament issues result in abnormal movement in the carpal rows, leading to a condition known as a flexion deformity. The deformity disrupts the normal rotational coupling of the carpal bones, leading to the "catch-up clunk" sound during extreme ulnar deviation[1][4]. Notably, up to 70% of Ehlers–Danlos syndrome patients, particularly those with the hypermobility type, experience painful mid-carpal laxity. However, this instability often tightens up over time, making it self-limiting in these patients.[5][6]
Dorsal mid-carpal Instability: Laxity in the palmar radioscapocapitate ligament results in dorsal subluxation of the mid-carpal joint. This creates a unique "subluxation clunk" sound, and is less common than palmar instability.
Extrinsic mid-carpal Instability: This form is usually secondary to distal radius malunions that result in malalignment. This causes a dorsal displacement of the distal radius and an adaptive Z-deformity in the carpal bones[7].
Characteristics/Clinical Presentation
Patients with mid-carpal instability typically present a range of symptoms, which may include wrist pain, clicking or snapping sounds, and reduced functional ability such as loss of strength and impaired prehension. Interestingly, many patients do not have a history of traumatic events. The symptoms can differ based on the specific subtype of mid-carpal instability:
In the case of Palmar Mid-carpal Instability (PMC), the proximal row stays flexed, instead of extending properly, when moving toward ulnar deviation. In addition to a "catch-up clunk" sound with extreme ulnar deviation, during which the proximal row of wrist bones (scaphoid, lunate, triquetrum) suddenly shifts back into place, patients may find that activities requiring flexion exacerbate wrist pain[8]. The subtype, Dorsal Mid-carpal Instability, is often marked by dorsal wrist pain and a distinct "subluxation clunk" during wrist movements. Extrinsic Mid-carpal Instability presents with Persistent pain, particularly when lifting objects, is common. This subtype may also present with a deformity in wrist alignment. Discomfort, laxity, and an uncomfortable feeling in the wrist are also frequent complaints in all the subtypes.
Differential Diagnosis
When assessing mid-carpal instability, it's crucial to rule out other conditions that may present similar symptoms. These can include:
- Carpal Tunnel Syndrome: Characterised by numbness and tingling, particularly in the thumb and fingers.
- Wrist Arthritis: Involves joint pain and may show radiographic changes.
- Wrist Sprain or Fracture: Acute pain and swelling, often following a traumatic event.
- Triangular Fibrocartilage Complex (TFCC) Tears: Present with ulnar-sided wrist pain and may show positive findings on imaging tests like MRI.
- Ganglion Cysts: These can cause localised pain and may be visible as a lump near the wrist joint.
Diagnostic Procedures
For an accurate diagnosis of mid-carpal instability, often involves a combination of clinical assessment and imaging techniques.
Radiology
While standard X-rays, wrist arthrography, and MRI are generally not useful for directly diagnosing mid-carpal instability due to its dynamic nature, they are valuable for ruling out other conditions like fractures or lunotriquetral dissociation. These imaging techniques can also assess joint surfaces prior to surgical interventions. In cases of Palmar mid-carpal Instability (PMCI), MRI may show a VISI (Volar Intercalated Segmental Instability) pattern[9].
Fluoroscopy
Fluoroscopy is often the primary imaging method for diagnosing mid-carpal instability.[10] It provides real-time insights into wrist joint movement. In patients with Palmar mid-carpal Instability (PMCI), a lateral view during radioulnar deviation often reveals a jump in the proximal row from flexion to extension. For those with Dorsal mid-carpal Instability (DMCI), dorsal subluxation of the capitate on the lunate becomes evident when pushing the capitate dorsally. This action not only produces a recognisable click but also causes patient apprehension, serving as a diagnostic sign.[11] [12]
Outcome Measures
Effective treatment of mid-carpal instability hinges on accurate outcome measurement tools. Some commonly used metrics include:
- Visual Analogue Scale (VAS): For pain assessment.
- Patient-Rated Wrist Evaluation (PRWE): Measures wrist pain and function.
- Range of Motion (ROM): Assesses wrist flexibility and movement limitations.
- Grip Strength: Measures the wrist and hand's ability to grasp objects securely.
Examination
A thorough clinical examination is key for the diagnosis of mid-carpal instability. Key components include:

Physical Inspection: Check for visible deformities, swelling, or redness. A palmar sag on the ulnar side of the carpus can be observed when the wrist is in neutral deviation, which often disappears with extreme ulnar deviation.
Palpation: Feel the wrist and surrounding areas for tenderness, especially over the ulnar carpus at the triquetrohamate joint. Localised synovitis may also be present.
Range of Motion Tests: Assess wrist flexibility and movement limitations, including a noticeable and painful clunk on the ulnar side during active ulnar deviation.
Provocative Tests: Reproducing symptoms through tests like the mid-carpal shift test, which is often positive in these patients.
Neurological Exam: Ruling out similar conditions such as carpal tunnel syndrome. A prominent ulnar head can often be observed when the wrist is in a neutral position.
Management
Management of mid-carpal instability often involves a combination of non-surgical and surgical treatments, tailored to the severity and specific needs of the patient.[1][4][12] It's management is still in debate and no single intervention is detected as the best.[2]
In order to meet all of the patient's needs, a multidisciplinary team approach is adopted and involves not only medical specialists like surgeons, rheumatologists, and radiologists but also healthcare professionals such as physiotherapists and occupational therapists. This well-rounded team plays a crucial role in both diagnosis and treatment planning, focusing on effective recovery that addresses physical symptoms as well as functional and emotional aspects of living with MCI.
Non-surgical Treatment
Before exploring surgical avenues, it's essential to explore non-surgical management methods for Palmar mid-carpal Instability (PMCI). Common non-surgical treatments involve activity adjustment, proprioceptive retraining and may be suggested along with[13]:
- Wrist Braces or Splints: Useful for providing support and restricting abnormal movements and was helpful for short term, but it still has limited success and not fix the instability completely on long term[2].
- Physiotherapy: Emphasises strengthening exercises and joint stabilisation.
- Pain Management: Via over-the-counter or prescribed medications.
Surgical Treatment
For patients who find little or no relief through non-surgical methods, surgical options may be recommended as the next step. The selection of a particular surgical method may depend on the individual symptoms and underlying causes according to the type and grade of the instability[13]:
- Ligament-Specific Augmentation: If ligaments are weakened and the ligament laxity can be pinpointed to a specific location, reinforcing the ligament may be beneficial. This is achieved through autografts, allografts, or synthetic materials.
- Ligament Reconstruction: This involves replacing the damaged ligament entirely. A graft is often taken, or rerouted, from another ligament and is indicated when a ligament is severely damaged or torn. [13]
- Soft Tissue Procedures: Such as distal advancement of the volar arcuate ligament or dorsal radiocarpalcapsulodesis, used in mild to moderate cases.
- mid-carpal Arthrodesis: Employed in severe cases, and includes 4-quadrant fusions, radial fusions, or triquetrohamate fusion[8].
- Arthroscopic Thermal capsular shrinkage: For dynamic instability[14]
- Treatment for Extrinsic MCI: Consists of radial shortening, radial osteotomy, or ulnar lengthening.
- Treatment for Dorsal MCI: Involves closing the space of Poirier by imbricating specific palmar ligaments[2].
Physiotherapy Management
Physiotherapy plays a vital role in the management of mid-carpal instability, offering both preventive and rehabilitative approaches.
Splint Immobilisation
Gutter splints are often used in conjunction with a pisiform boost pad. This pisiform boost pad is often combined with a dorsal pressure pad over the ulnar head. Modified perilunate stabilising splints can be used if other methods are not successful in controlling the subluxation. This forearm based wrist support splint controls the scaphoid and the scaphotrapezial trapezoid joint by exerting dorsally directed pressure on the scaphoid tuberosity and the trapezoid ridge. This controls flexion tendency of the proximal carpal row by dorsally directed pressure on the pisiform. [12]
Phase 1
Once symptom reduction is observed, start with static and proprioceptive training, while keeping the wrist in neutral position (±20° of dorsal flexion, with the third metacarpal aligned with the forearm) with exercise and light daily activities is recommended as the first phase. Start isometric exercise to improve static stability and strengthening wrist and hand extrinsic muscles specifically the pronators. At this phase our aim for patients to maintain a neutral wrist position with and without looking at their wrist. Once achieved, they moved to the next phase[15].
Phase 2 (Dynamic Strengthening Exercises)
Once symptom reduction is observed, focus shifts to strengthening specific muscles including the M. flexor carpi ulnaris, M. flexor carpi radialis, and M. extensor carpi radialis longus and brevis.
Palmar flexion and Dorsiflexion exercises

Table Exercise: With your forearm fixed on a table, use weights or a Thera band to slowly lift your hand upwards. Increase resistance as you progress.
Wrist Roll: Stand with arms extended holding a roller. Slowly roll the chain up and down using wrist motion, keeping the rest of your body stationary. Add weights for more resistance.
Ulnar and Radial Deviation exercises

Arm Extension Exercise: With your arm extended and holding a weight or using a theraband, move your hand forwards for radial deviation and backwards for ulnar deviation.
A study used wrist exercise program for palmar mid-carpal instability and found there was acceptable improvement in functional level and quality of life on long-term follow up[16], this program used: Exercises for proper wrist and hand positioning, Used to keep the wrist in a neutral or straight position during activities like lifting. May include using supportive bandages or hand positioning recommendations to prevent strain. Exercises for Wrist Stabilization to improve wrist strength and control. Included activities like Powerball exercises, dynamic dumbbell workouts, and stabilisation drills using objects (e.g., a stock)
Occupational Therapy Management
Occupational therapists (OTs) also play a major role in rehabilitating patients with Mid-carpal Instability (MCI). They focus on enabling patients to engage in everyday activities, minimising pain, and enhancing wrist stability and function. Their aim is to facilitate independence in daily living and work tasks. This involves setting achievable, patient-centred goals aimed at symptom management, function restoration, and quality-of-life improvement.
Functional Assessment and Adaptation: Evaluate the patient's ability to perform essential tasks and recommend ergonomic adaptations for work and home settings.
Splinting and Orthotic Management: Provide specialised splints to improve wrist stability, often customising them to meet individual needs.
Pain Management Strategies: Employ non-pharmacological methods, such as thermal modalities and soft tissue mobilisation, to manage symptoms.
Develop a tailored rehabilitation programme: which may include Strengthening, ROM exercises and Activity pacing strategies
Education and Training: Teach patients about wrist anatomy and MCI, compensatory movements, and techniques to avoid exacerbation of symptoms.
Activity Re-Training: Instruct on techniques and aids for daily living tasks such as cooking, writing, and other hand-intensive activities.
Conclusion
Mid-carpal Instability is a complex wrist condition that necessitates a comprehensive diagnostic and management approach. Management is a multidisciplinary effort, requiring input from various healthcare professionals to offer comprehensive care. While physiotherapists mainly target functional recovery and muscular strengthening, occupational therapists concentrate on facilitating the patient's return to everyday activities and work tasks, offering a holistic approach to rehabilitation. A blend of surgical and nonsurgical interventions, physiotherapy, and occupational therapy can lead to significant improvements in patient outcomes.
References
- ↑ 1.0 1.1 1.2 Lichtman DM, Wroten ES. Understanding Midcarpal Instability. Journal of Hand Surgery [AM]. 2006; 31A:491–498
- ↑ 2.0 2.1 2.2 2.3 von Schroeder HP. Dorsal wrist plication for midcarpal instability. The Journal of hand surgery. 2018 Apr 1;43(4):354-9.
- ↑ 3.0 3.1 Jing SS, Smith G, Deshmukh S. Demystifying palmar midcarpal instability. Journal of Wrist Surgery. 2020 Aug 27;10(02):094-101.
- ↑ 4.0 4.1 Buchler U. Wrist instability. Ln: Gaenslen ES, Lichtman DM. Midcarpal instability: description, classification, and treatment. First ed. UK; The livery house, 1996. pg 163-168
- ↑ Niacaris T, Ming BW, Lichtman DM. Midcarpal instability: a comprehensive review and update. Hand Clin 2015;31(03):487–493
- ↑ 1 Woerdeman LAE, Ritt MJPF, Meijer B, Maas M. Wrist problems in patients with Ehlers-Danlos syndrome. Eur J Plast Surg 2000; 23:208–210
- ↑ Rabinovich RV, Rahman OF, Nasra MH, Polatsch DB, Beldner S. Midcarpal instability. JAAOS-Journal of the American Academy of Orthopaedic Surgeons. 2023 Aug 1;31(15):834-44.
- ↑ 8.0 8.1 Shiga SA, Werner FW, Garcia-Elias M, Harley BJ. Biomechanical analysis of palmar midcarpal instability and treatment by partial wrist arthrodesis. The Journal of Hand Surgery. 2018 Apr 1;43(4):331-8.
- ↑ Toms AP, Chojnowski A, Cahir JG. Midcarpal instability: a radiological perspective. Skeletal radiology. 2011 May;40:533-41.
- ↑ Braunstein EM et al. Fluoroscopic and arthrographic evaluation of carpal instability. AJR Am J. Roentgenol.. 1985 Jun;14(6):1259-62
- ↑ Slutsky D, Osterman A. Fractures and Injuries of the Distal Radius and Carpus. Ln: Carlos Heras-Palou MD. Midcarpal instability. First ed. Philadelphia: Saunders Elsevier, 2008
- ↑ 12.0 12.1 12.2 Cooney WP. The wrist: Diagnosis and operative treatment. 2nd ed. Philadelphia, PA,:Lippincott Williams & Wilkins; 2010.pg 655-666
- ↑ 13.0 13.1 13.2 Ming BW, Niacaris T, Lichtman DM. Surgical techniques for the management of midcarpal instability. Journal of wrist surgery. 2014 Aug;3(03):171-4
- ↑ Higgin RP, Hargreaves DG. Midcarpal Instability: The Role of Wrist Arthroscopy. Hand Clinics. 2017 Nov 1;33(4):717-26.
- ↑ Brands M, Selles RW, van Kooij YE, Feitz R, Videler AJ, Slijper HP, Wouters RM. Outcomes of an exercise program in patients with dorsal or volar midcarpal laxity: a cohort study of 213 patients. Disability and Rehabilitation. 2024 Apr 23;46(9):1825-31.
- ↑ Mulders MA, Sulkers GS, Videler AJ, Strackee SD, Smeulders MJ. Long-term functional results of a wrist exercise program for patients with palmar midcarpal instability. Journal of wrist surgery. 2018 Jul;7(03):211-8.