Multiple Autoimmune Syndrome (MAS): Difference between revisions
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== Mechanism of Injury / Pathological Process == | == Mechanism of Injury / Pathological Process == | ||
The pathogenesis of MAS is unclear but to date environmental and | The pathogenesis of MAS is unclear but to date environmental, infectious, psychological, genetic, and immunologic susceptibility are being investigated. A three group classification has been developed which clusters together the autoimmune diseases that tend to occur together. | ||
1.MAS includes myasthenia gratis, thymoma, polymyositis and giant cell myocarditis | |||
2.MAS includes Sjogren's syndrome, RA, scleroderma, autoimmune thyroid disease . | |||
3.MAS includes SLE, DM1, Sjogren's syndrome, Addison's disease, vitiligo, dermatitis herpetiformis, autoimmune thyroid disease.<ref name=":0" /><br> | |||
== Clinical Presentation == | == Clinical Presentation == | ||
[[File:Joint swelling.jpg|thumb]] | [[File:Joint swelling.jpg|thumb]] | ||
When a person presents to physiotherapy for treatment related to an autoimmune disease eg RA or has a diagnosis of an autoimmune disease it is imperative to look into their medical history to see if other autoimmune diseases are present or possible further investigations are warranted for possibility of other autoimmune diseases. This is important as up to one in four persons with an autoimmune disease has a tendency to develop another<ref name=":0" /><br> | When a person presents to physiotherapy for treatment related to an autoimmune disease eg RA or has a diagnosis of an autoimmune disease it is imperative to look into their medical history to see if other autoimmune diseases are present or possible further investigations are warranted for possibility of other autoimmune diseases. This is important as up to one in four persons with an autoimmune disease has a tendency to develop another<ref name=":0" /> For clinical presentation of specific [[Autoimmune Disorders|autoimmune diseases]] follow links above.<br> | ||
== Diagnostic Procedures == | == Diagnostic Procedures == | ||
Revision as of 06:51, 9 February 2019
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Clinically Relevant Anatomy[edit | edit source]
Multiple autoimmune syndrome is a condition in which a minimum of three distinct autoimmune diseases have been diagnosed in a person.[1].Autoimmune diseases are chronic disabling conditions that occur when a persons own immune systems turns on itself. Any once healthy cells, tissues and organs can be involved and can lead to a diverse set of changes within the body depending on the autoimmune disease that is diagnosed. Examples of autoimmune disease are; fibromyalgia; HIV/AIDS; Lyme disease; Systemic Lupus Erythematosus; Rheumatoid Arthritis; Psoriatic Arthritis.
Mechanism of Injury / Pathological Process[edit | edit source]
The pathogenesis of MAS is unclear but to date environmental, infectious, psychological, genetic, and immunologic susceptibility are being investigated. A three group classification has been developed which clusters together the autoimmune diseases that tend to occur together.
1.MAS includes myasthenia gratis, thymoma, polymyositis and giant cell myocarditis
2.MAS includes Sjogren's syndrome, RA, scleroderma, autoimmune thyroid disease .
3.MAS includes SLE, DM1, Sjogren's syndrome, Addison's disease, vitiligo, dermatitis herpetiformis, autoimmune thyroid disease.[1]
Clinical Presentation[edit | edit source]
When a person presents to physiotherapy for treatment related to an autoimmune disease eg RA or has a diagnosis of an autoimmune disease it is imperative to look into their medical history to see if other autoimmune diseases are present or possible further investigations are warranted for possibility of other autoimmune diseases. This is important as up to one in four persons with an autoimmune disease has a tendency to develop another[1] For clinical presentation of specific autoimmune diseases follow links above.
Diagnostic Procedures[edit | edit source]
Outcome Measures[edit | edit source]
add links to outcome measures here (see Outcome Measures Database)
Management / Interventions[edit | edit source]
add text here relating to management approaches to the condition
Differential Diagnosis[edit | edit source]
add text here relating to the differential diagnosis of this condition
Resources[edit | edit source]
add appropriate resources here
