Immunotherapy: Difference between revisions

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Immunotherapy is the use of drugs (e.g., immunosuppressors), biologicals (e.g., cytokines, monoclonal antibodies), vitamins and minerals (e.g., zinc, vitamin C, and vitamin B6), transplantation (e.g., [[Bone Marrow|bone marrow]]) and immunizations (e.g., prophylactic and therapeutic [[Vaccines|vaccine]]<nowiki/>s) to control [[Immune System|immune responses]] in diverse directions.
Immunotherapy is the use of drugs (e.g., immunosuppressors), biologicals (e.g., cytokines, monoclonal antibodies), vitamins and minerals (e.g., zinc, vitamin C, and vitamin B6), transplantation (e.g., [[Bone Marrow|bone marrow]]) and immunizations (e.g., prophylactic and therapeutic [[Vaccines|vaccine]]<nowiki/>s) to control [[Immune System|immune responses]] in diverse directions.


Immunotherapy works to upregulate or downregulate the immune system to achieve a therapeutic effect in immunological mediated disorders including: [[Oncology|malignancies]]; immunodeficiencies; hypersensitivity reactions; [[Autoimmune Disorders|autoimmune diseases]], tissue and organ transplantations; inflammatory disorders; [[Communicable Diseases|infectious diseases]]; and any other disease where immunotherapy can improve the [[Quality of Life|quality]] of life  and survival.<ref>Justiz AV, Zito PM. [https://www.ncbi.nlm.nih.gov/books/NBK519046/ Immunotherapy].22.6.2020 Available from: https://www.ncbi.nlm.nih.gov/books/NBK519046/<nowiki/>(last accessed 4.9.2020)</ref>
Immunotherapy
* Any form of treatment that uses the body's natural abilities that constitute the immune system to fight infection and disease or to protect the body from some of the side effects of treatment.
* Works to upregulate or downregulate the immune system to achieve a therapeutic effect in immunological mediated disorders including: [[Oncology|malignancies]]; immunodeficiencies; hypersensitivity reactions; [[Autoimmune Disorders|autoimmune diseases]], tissue and organ transplantations; inflammatory disorders; [[Communicable Diseases|infectious diseases]]; and any other disease where immunotherapy can improve the [[Quality of Life|quality]] of life  and survival.<ref>Justiz AV, Zito PM. [https://www.ncbi.nlm.nih.gov/books/NBK519046/ Immunotherapy].22.6.2020 Available from: https://www.ncbi.nlm.nih.gov/books/NBK519046/<nowiki/>(last accessed 4.9.2020)</ref>


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== Types of Cancer Immunotherapy ==
Monoclonal antibodies (MABs)
 
Some MABs have an effect on the immune system. So as well as being a targeted cancer drug, they are also a type of immunotherapy.
 
Checkpoint Inhibitors
 
Checkpoint inhibitors are used to treat cancers such as melanoma skin cancer and lung cancer. Researchers are also looking at them in clinical trials for other types of cancer.
 
Cytokines
 
Cytokines are a group of proteins that are found naturally in the body. They help to boost the immune system. Man made versions of these proteins have been developed as a treatment for cancer.
 
Vaccines to treat cancer
 
Cancer vaccines are a type of immunotherapy. Research in this area is at an early stage and vaccines are mainly available as part of clinical trials.
 
CAR T-cell therapy
 
This type of immunotherapy is still quite new and researchers are looking into how well it works as a treatment for


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Revision as of 07:18, 4 September 2020

This article or area is currently under construction and may only be partially complete. Please come back soon to see the finished work! (4/09/2020)

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton, Kim Jackson and Vidya Acharya  

Introduction[edit | edit source]

Immunotherapy is the use of drugs (e.g., immunosuppressors), biologicals (e.g., cytokines, monoclonal antibodies), vitamins and minerals (e.g., zinc, vitamin C, and vitamin B6), transplantation (e.g., bone marrow) and immunizations (e.g., prophylactic and therapeutic vaccines) to control immune responses in diverse directions.

Immunotherapy

  • Any form of treatment that uses the body's natural abilities that constitute the immune system to fight infection and disease or to protect the body from some of the side effects of treatment.
  • Works to upregulate or downregulate the immune system to achieve a therapeutic effect in immunological mediated disorders including: malignancies; immunodeficiencies; hypersensitivity reactions; autoimmune diseases, tissue and organ transplantations; inflammatory disorders; infectious diseases; and any other disease where immunotherapy can improve the quality of life and survival.[1]

Types of Cancer Immunotherapy[edit | edit source]

Monoclonal antibodies (MABs)

Some MABs have an effect on the immune system. So as well as being a targeted cancer drug, they are also a type of immunotherapy.

Checkpoint Inhibitors

Checkpoint inhibitors are used to treat cancers such as melanoma skin cancer and lung cancer. Researchers are also looking at them in clinical trials for other types of cancer.

Cytokines

Cytokines are a group of proteins that are found naturally in the body. They help to boost the immune system. Man made versions of these proteins have been developed as a treatment for cancer.

Vaccines to treat cancer

Cancer vaccines are a type of immunotherapy. Research in this area is at an early stage and vaccines are mainly available as part of clinical trials.

CAR T-cell therapy

This type of immunotherapy is still quite new and researchers are looking into how well it works as a treatment for

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Resources[edit | edit source]

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References[edit | edit source]

  1. Justiz AV, Zito PM. Immunotherapy.22.6.2020 Available from: https://www.ncbi.nlm.nih.gov/books/NBK519046/(last accessed 4.9.2020)