Myoglobin
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton
Introduction[edit | edit source]
Myoglobin (Hb) is an iron-containing heme protein that is present predominantly in the sarcoplasm of skeletal and cardiac muscles. Due to the presence of heme moiety, myoglobin serves as a carrier and store for oxygen in muscle cells of the body. Myoglobin has more affinity for oxygen as compared to hemoglobin. As a result, it can acquire oxygen from hemoglobin, hence transferring it from the blood to the muscle tissues.[1]
IMAGE 1: Cartoon representation of Myoglobin (blue) with heme group (orange)
Here is the basic information Mb.
- It is a low molecular weight oxygen-binding heme protein and is one of the most important proteins in the human body.
- It acts as an oxygen reservoir unit, suppling oxygen to working muscles.
- It is mainly found in the heart and skeletal muscle cells, occurring in the highest concentration in the striated muscles of vertebrates.
- In skeletal muscle it serves to transport oxygen from the cell membrane to the mitochondria.
- Diving mammals such as seals and whales are able to remain submerged for long periods because they have greater amounts of myoglobin in their muscles than other animals do[2].
The effect of endurance training on myoglobin concentrations[edit | edit source]
Aerobic workouts/endurance training trigger important metabolic changes in muscle tissue, including an increase in mitochondria and the protein myoglobin. Mitochondria (the powerhouses of the cells) are necessary for creating ATP for energy. Myoglobin, on the other hand brings in the oxygen needed for that process. These changes improve the aerobic capacity of muscles. ie Endurance exercise can increase the amount of myoglobin in a cell, as increased aerobic respiration increases the need for oxygen[3].
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References[edit | edit source]
- ↑ Anwar MY, Gupta V. Myoglobinuria. StatPearls [Internet]. 2021 Feb 6.Available:https://www.ncbi.nlm.nih.gov/books/NBK557379/ (accessed 23.11.2021)
- ↑ Biochem Myoglobin Available:https://biochemden.com/myoglobin/ (accessed 23.11.2021)
- ↑ Idsemergency management Myoglobin Available:https://www.idsemergencymanagement.com/2021/07/23/does-myoglobin-increase-with-exercise/ (accessed 23.11.2021)
