Multiple Autoimmune Syndrome (MAS): Difference between revisions

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== Clinically Relevant Anatomy  ==
== Clinically Relevant Anatomy  ==


Multiple autoimmune syndrome is a condition in which a minimum of three distinct autoimmune diseases have been diagnosed in a person.<ref name=":0">Cojocaru M, Cojocaru IM, Silosi I. Multiple autoimmune syndrome. Maedica. 2010 Apr;5(2):132.</ref>.Autoimmune diseases are chronic disabling conditions that occur when a persons own immune systems turns on itself. Any once healthy cells, tissues and organs can be involved and can lead to a diverse set of changes within the body depending on the autoimmune disease that is diagnosed. Examples of autoimmune disease are; [[fibromyalgia]]; [[HIV/AIDS]]; [[Lyme Disease|Lyme disease]]; [[Systemic Lupus Erythematosus]]; [[Rheumatoid Arthritis]]; [[Psoriatic Arthritis]].
Multiple autoimmune syndrome is a condition in which a minimum of three distinct [[Autoimmune Disorders|autoimmune]] diseases have been diagnosed in a person.<ref name=":0">Cojocaru M, Cojocaru IM, Silosi I. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150011/ Multiple autoimmune syndrome]. Maedica. 2010 Apr;5(2):132.</ref>.Autoimmune diseases are chronic disabling conditions that occur when a persons own immune systems turns on itself. Any once healthy cells, tissues and organs can be involved and can lead to a diverse set of changes within the body depending on the autoimmune disease that is diagnosed. Examples of autoimmune disease are; [[fibromyalgia]]; [[Human Immunodeficiency Virus (HIV)]]; [[Lyme Disease|Lyme disease]]; [[Systemic Lupus Erythematosus]]; [[Rheumatoid Arthritis]]; [[Psoriatic Arthritis]].
[[File:Anatomy pic.jpg|thumb|287x287px]]
[[File:Anatomy pic.jpg|287x287px|left|frameless]]
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A three group classification has been developed which clusters together the autoimmune diseases that tend to occur together.


1.MAS includes myasthenia gratis, thymoma, polymyositis and giant cell myocarditis
A '''three group classification''' has been developed which clusters together the autoimmune diseases that tend to occur together.They are simply called Type 1 MAS Type 2 MAS or Type 3 MAS


2.MAS includes Sjogren's syndrome, RA, scleroderma, autoimmune thyroid disease .
Type 1 MAS includes myasthenia gratis, thymoma, polymyositis and giant cell [[Myocardial Infarction|myocarditis]]


3.MAS includes SLE, DM1, Sjogren's syndrome, Addison's disease, vitiligo, dermatitis herpetiformis, autoimmune thyroid disease.<ref name=":0" /><br>
Type 2 MAS includes Sjogren's syndrome, RA, scleroderma, autoimmune [[Thyroid Storm (Thyroid Crisis)|thyroid]] disease .


== Clinical Presentation   ==
Type 3 MAS includes SLE, DM1, [[Sjogren's Syndrome|Sjogren's]] syndrome, [[Addison's Disease|Addison's]] disease, vitiligo, dermatitis herpetiformis, autoimmune thyroid disease.<ref name=":0" /><br>
[[File:Joint swelling.jpg|thumb]]
 
[[File:Assessment table NEW.jpg|thumb]]
== Clinical Presentation[[File:Joint_swelling.jpg|frameless]]   ==
[[File:Chronic-fatigue-syndrome.jpg|right|frameless]]
When a person presents to physiotherapy for treatment related to an autoimmune disease or has a diagnosis of an autoimmune disease in their medical history, be sure to check for the possibility of others [further investigations may be warranted]. This is important as up to one in four persons with an autoimmune disease has a tendency to develop another<ref name=":0" /> For clinical presentation of specific [[Autoimmune Disorders|autoimmune diseases]] follow the former link
When a person presents to physiotherapy for treatment related to an autoimmune disease or has a diagnosis of an autoimmune disease in their medical history, be sure to check for the possibility of others [further investigations may be warranted]. This is important as up to one in four persons with an autoimmune disease has a tendency to develop another<ref name=":0" /> For clinical presentation of specific [[Autoimmune Disorders|autoimmune diseases]] follow the former link
== Outcome Measures  ==
== Outcome Measures  ==
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== Management / Interventions  ==
== Management / Interventions  ==
[[File:Health-benefits-of-physical-activity.png|thumb|left]]
[[File:Health-benefits-of-physical-activity.png|thumb|left]]
For clients living with a chronic autoimmune disease physiotherapy can be immensely beneficial for the ailments associated with the condition.
For clients living with a chronic autoimmune disease physiotherapy can be immensely beneficial for the ailments associated with the condition.<ref name=":1">PDH academy.[https://pdhtherapy.com/2018/02/how-can-physical-therapists-help-people-with-autoimmune-disorders/ How can physical therapists help people with Autoimmune Disorders]. 14.2.2018</ref>


For individual autoimmune diseases the physiotherapy protocols will be the same but with MAS a long term educational holistic view is warranted more than ever.  
For individual autoimmune diseases the physiotherapy protocols will be the same but with MAS a long term educational holistic view is warranted more than ever.  


Symptoms such as joint swelling, muscle wasting, pain, fatigue, inflammation, isolation and depression can all be addressed. Tailored physical activity programs are a fantastic way to improve every levels, decrease stress , increased sense of well being and the myriad of physiological benefits. Specific, general and holistic techniques  can be employed eg individual tailored exercise programs, pain education, hydrotherapy, energy conservation, diet plans and advice, group exercise participation, goal orientated activities.
Symptoms such as joint swelling, muscle wasting,  increased falls risk due to loss of neurological coordination, pain, [[Fatigue Severity Scale|fatigue]], inflammation, isolation and depression can all be addressed.<ref>Jan Tregre, DPT, Southern Physical Therapy and Women’s Therapy Center. [http://www.healthycellsmagazine.com/articles/how-physical-therapy-can-Ahelp-with-autoimmune-diseases How physical therapy can help with autoimmune diseases]. June 3 2014</ref>
 
Tailored [[Physical activity in Long Term usculoskeletal onditions|physical activity]] programs are a fantastic way to improve energy levels, decrease stress , increased a persons sense of well being and a myriad of physiological benefits. Specific and general  techniques  can be employed eg individual tailored [[Physical Activity in Long Term Musculoskeletal Conditions|exercise programs]], [[Pain Neuroscience Education (PNE)|pain education]], [[Aquatherapy|hydrotherapy]], [[balance]] training, energy conservation, diet plans/ advice, group exercise participation, goal orientated activities.<ref name=":1" />


A tailored walking program is often an option.
A tailored walking program is often an option.
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== Resources    ==
== Resources    ==
https://www.autoimmune.org.au/


see [[Autoimmune Disorders|autoimmune disorders]] resources  
see [[Autoimmune Disorders|autoimmune disorders]] resources  
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<references />
<references />
[[Category:Autoimmune disorders|Autoimmune Disorders]]
[[Category:Autoimmune Disorders]]
[[Category:Syndromes]]
[[Category:Syndromes]]
[[Category:Non Communicable Diseases]]
[[Category:Conditions]]

Latest revision as of 14:03, 16 December 2022

Original Editor - User:Lucinda hampton Top Contributors - Lucinda hampton, Kim Jackson, Leana Louw and Rishika Babburu

Clinically Relevant Anatomy[edit | edit source]

Multiple autoimmune syndrome is a condition in which a minimum of three distinct autoimmune diseases have been diagnosed in a person.[1].Autoimmune diseases are chronic disabling conditions that occur when a persons own immune systems turns on itself. Any once healthy cells, tissues and organs can be involved and can lead to a diverse set of changes within the body depending on the autoimmune disease that is diagnosed. Examples of autoimmune disease are; fibromyalgia; Human Immunodeficiency Virus (HIV); Lyme disease; Systemic Lupus Erythematosus; Rheumatoid Arthritis; Psoriatic Arthritis.

Anatomy pic.jpg


Mechanism of Injury / Pathological Process[edit | edit source]

The pathogenesis of MAS is unclear but to date environmental, infectious, psychological, genetic, and immunologic susceptibility are being investigated.

[2]


A three group classification has been developed which clusters together the autoimmune diseases that tend to occur together.They are simply called Type 1 MAS Type 2 MAS or Type 3 MAS

Type 1 MAS includes myasthenia gratis, thymoma, polymyositis and giant cell myocarditis

Type 2 MAS includes Sjogren's syndrome, RA, scleroderma, autoimmune thyroid disease .

Type 3 MAS includes SLE, DM1, Sjogren's syndrome, Addison's disease, vitiligo, dermatitis herpetiformis, autoimmune thyroid disease.[1]

Clinical PresentationJoint swelling.jpg[edit | edit source]

Chronic-fatigue-syndrome.jpg

When a person presents to physiotherapy for treatment related to an autoimmune disease or has a diagnosis of an autoimmune disease in their medical history, be sure to check for the possibility of others [further investigations may be warranted]. This is important as up to one in four persons with an autoimmune disease has a tendency to develop another[1] For clinical presentation of specific autoimmune diseases follow the former link

Outcome Measures[edit | edit source]

The outcome measures chosen will vary depending on the autoimmune diseases present.

(see individual autoimmune condition outcome measures)

Management / Interventions[edit | edit source]

Health-benefits-of-physical-activity.png

For clients living with a chronic autoimmune disease physiotherapy can be immensely beneficial for the ailments associated with the condition.[3]

For individual autoimmune diseases the physiotherapy protocols will be the same but with MAS a long term educational holistic view is warranted more than ever.

Symptoms such as joint swelling, muscle wasting, increased falls risk due to loss of neurological coordination, pain, fatigue, inflammation, isolation and depression can all be addressed.[4]

Tailored physical activity programs are a fantastic way to improve energy levels, decrease stress , increased a persons sense of well being and a myriad of physiological benefits. Specific and general techniques can be employed eg individual tailored exercise programs, pain education, hydrotherapy, balance training, energy conservation, diet plans/ advice, group exercise participation, goal orientated activities.[3]

A tailored walking program is often an option.

[5]

In conclusion note that is important with chronic life changing diseases to take a holistic approach including specific and varied physiotherapy skills, good patient education and family/ carers inclusion.


Resources[edit | edit source]

https://www.autoimmune.org.au/

see autoimmune disorders resources

References[edit | edit source]

  1. 1.0 1.1 1.2 Cojocaru M, Cojocaru IM, Silosi I. Multiple autoimmune syndrome. Maedica. 2010 Apr;5(2):132.
  2. Demystifying Medicine.What are autoimmune diseases.https://www.youtube.com/watch?v=ZLh2rfZuvdE [last accessed 10/2/2019],
  3. 3.0 3.1 PDH academy.How can physical therapists help people with Autoimmune Disorders. 14.2.2018
  4. Jan Tregre, DPT, Southern Physical Therapy and Women’s Therapy Center. How physical therapy can help with autoimmune diseases. June 3 2014
  5. Michelle Spring.Walking is the perfect exercise for autoimmune diseases. Available from: https://www.youtube.com/watch?v=cadrfVIH8uw [last accessed 11.2.2019]