Myoglobin: Difference between revisions

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== Introduction ==
== Introduction ==
Myoglobin (Hb) is an iron-containing heme protein that is present predominantly in the sarcoplasm of skeletal and cardiac muscles. Due to the presence of heme moiety, myoglobin serves as a carrier and store for oxygen in muscle cells of the body. Myoglobin has more affinity for oxygen as compared to hemoglobin. As a result, it can acquire oxygen from hemoglobin, hence transferring it from the blood to the muscle tissues.<ref>Anwar MY, Gupta V. [https://www.ncbi.nlm.nih.gov/books/NBK557379/ Myoglobinuria]. StatPearls [Internet]. 2021 Feb 6.Available:https://www.ncbi.nlm.nih.gov/books/NBK557379/ (accessed 23.11.2021)</ref>
[[File:Myoglobin and heme.png|right|frameless]]
Myoglobin (Hb) is an [[iron]]-containing heme [[Proteins|protein]] that is present predominantly in the sarcoplasm of [[Muscle Cells (Myocyte)|skeletal]] and [[Muscle: Cardiac|cardiac muscle]]<nowiki/>s. Due to the presence of heme moiety, myoglobin serves as a carrier and store for oxygen in muscle cells of the body. Myoglobin has more affinity for oxygen as compared to hemoglobin. As a result, it can acquire oxygen from hemoglobin, hence transferring it from the [[blood]] to the muscle tissues.<ref>Anwar MY, Gupta V. [https://www.ncbi.nlm.nih.gov/books/NBK557379/ Myoglobinuria]. StatPearls [Internet]. 2021 Feb 6.Available:https://www.ncbi.nlm.nih.gov/books/NBK557379/ (accessed 23.11.2021)</ref>
 
IMAGE 1: Cartoon representation of Myoglobin (blue) with heme group (orange)


Here is the basic information Mb.  
Here is the basic information Mb.  
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* It is a low molecular weight oxygen-binding heme protein and is one of the most important proteins in the human body.
* It is a low molecular weight oxygen-binding heme protein and is one of the most important proteins in the human body.
* It acts as an oxygen reservoir unit, suppling oxygen to working muscles.  
* It acts as an oxygen reservoir unit, suppling oxygen to working muscles.  
* It is mainly found in the heart and skeletal muscle cells, occurring in the highest concentration in the striated muscles of vertebrates.   
* It is mainly found in the [[Anatomy of the Human Heart|heart]] and [[Muscle|skeletal muscle]] cells, occurring in the highest concentration in the striated muscles of vertebrates. 
* In skeletal muscle it serves to transport oxygen from the cell membrane to the mitochondria.
* In skeletal muscle it serves to transport oxygen from the cell membrane to the [[mitochondria]].
* Diving mammals such as seals and whales are able to remain submerged for long periods because they have greater amounts of myoglobin in their muscles than other animals do<ref>Biochem [https://biochemden.com/myoglobin/ Myoglobin] Available:https://biochemden.com/myoglobin/ (accessed 23.11.2021)</ref>.  
* Diving mammals such as seals and whales are able to remain submerged for long periods because they have greater amounts of myoglobin in their muscles than other animals do<ref>Biochem [https://biochemden.com/myoglobin/ Myoglobin] Available:https://biochemden.com/myoglobin/ (accessed 23.11.2021)</ref>.  



Revision as of 05:39, 23 November 2021

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton  

Introduction[edit | edit source]

Myoglobin and heme.png

Myoglobin (Hb) is an iron-containing heme protein that is present predominantly in the sarcoplasm of skeletal and cardiac muscles. Due to the presence of heme moiety, myoglobin serves as a carrier and store for oxygen in muscle cells of the body. Myoglobin has more affinity for oxygen as compared to hemoglobin. As a result, it can acquire oxygen from hemoglobin, hence transferring it from the blood to the muscle tissues.[1]

IMAGE 1: Cartoon representation of Myoglobin (blue) with heme group (orange)

Here is the basic information Mb.

  • It is a low molecular weight oxygen-binding heme protein and is one of the most important proteins in the human body.
  • It acts as an oxygen reservoir unit, suppling oxygen to working muscles.
  • It is mainly found in the heart and skeletal muscle cells, occurring in the highest concentration in the striated muscles of vertebrates. 
  • In skeletal muscle it serves to transport oxygen from the cell membrane to the mitochondria.
  • Diving mammals such as seals and whales are able to remain submerged for long periods because they have greater amounts of myoglobin in their muscles than other animals do[2].  

Sub Heading 2[edit | edit source]

Sub Heading 3[edit | edit source]

Resources[edit | edit source]

  • bulleted list
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  1. numbered list
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References[edit | edit source]

  1. Anwar MY, Gupta V. Myoglobinuria. StatPearls [Internet]. 2021 Feb 6.Available:https://www.ncbi.nlm.nih.gov/books/NBK557379/ (accessed 23.11.2021)
  2. Biochem Myoglobin Available:https://biochemden.com/myoglobin/ (accessed 23.11.2021)