End Organ: Difference between revisions
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'''Original Editor '''- [[User: | '''Original Editor '''- [[User:Lucinda hampton|Lucinda hampton]] | ||
'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}} | '''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}} | ||
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== Introduction == | == Introduction == | ||
An end organ is the last organ affected in a chain of events, for instance a disease process. | An end organ is the last organ affected in a chain of events, for instance a disease process. Examples are the [[Liver Disease|liver]], [[Brain Anatomy|brain]], [[kidney]] or [[Anatomy of the Human Heart|heart.]] These organs are ultimately affected by a [[Chronic Disease|chronic]] or progressive disease or condition like [[diabetes]] or [[hypertension]] causing eg [[Chronic Kidney Disease|renal failure.]] | ||
Examples are the liver, brain, kidney or heart | |||
== Detection == | == Detection == | ||
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Classical pointers for end organ damage include: | Classical pointers for end organ damage include: | ||
* | * [[Stroke]], vascular and hemorrhagic | ||
* Retinopathy | * Retinopathy | ||
* Coronary heart disease/myocardial infarction and heart failure | * [[Coronary Artery Disease (CAD)|Coronary heart disease]]/[[Myocardial Infarction|myocardial infarction]] and [[Congestive Heart Failure|heart failure]] | ||
* Proteinuria | * Proteinuria | ||
* Renal failure | * [[Dialysis Case Study|Renal failure]] | ||
* Atherosclerotic change eg stenoses and aneurysms in the blood vessels.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref> | * [[Atherosclerosis|Atherosclerotic]] change eg stenoses and aneurysms in the blood vessels.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref> | ||
== Risk Factors == | == Risk Factors == | ||
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# Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment. | # Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment. | ||
# Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such. | # [[Obesity]] is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such. | ||
# Type 2 diabetes mellitus is associated with target organ damage | # [[Diabetes Mellitus Type 2|Type 2 diabetes mellitus]] is associated with target organ damage | ||
== Viewing == | |||
Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".{{#ev:youtube|v=WVFbsgg1c_Q}}<ref>MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]</ref> | |||
== References == | == References == | ||
<references /> | <references /> | ||
Latest revision as of 06:58, 10 May 2024
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton
Introduction[edit | edit source]
An end organ is the last organ affected in a chain of events, for instance a disease process. Examples are the liver, brain, kidney or heart. These organs are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension causing eg renal failure.
Detection[edit | edit source]
Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.
Classical pointers for end organ damage include:
- Stroke, vascular and hemorrhagic
- Retinopathy
- Coronary heart disease/myocardial infarction and heart failure
- Proteinuria
- Renal failure
- Atherosclerotic change eg stenoses and aneurysms in the blood vessels.[1]
Risk Factors[edit | edit source]
Many and varied and include:
- Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
- Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
- Type 2 diabetes mellitus is associated with target organ damage
Viewing[edit | edit source]
Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".
References[edit | edit source]
- ↑ Schmieder RE. End organ damage in hypertension. Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)
- ↑ MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]
