End Organ: Difference between revisions

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'''Original Editor '''- [[User:User Name|User Name]]
'''Original Editor '''- [[User:Lucinda hampton|Lucinda hampton]]


'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}}  &nbsp;   
'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}}  &nbsp;   
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== Introduction ==
== Introduction ==
An end organ is the last  organ affected in a chain of events, for instance a disease process.  
An end organ is the last  organ affected in a chain of events, for instance a disease process. Examples are the [[Liver Disease|liver]], [[Brain Anatomy|brain]], [[kidney]] or [[Anatomy of the Human Heart|heart.]] These organs are ultimately affected by a [[Chronic Disease|chronic]] or progressive disease or condition like [[diabetes]] or [[hypertension]] causing eg [[Chronic Kidney Disease|renal failure.]]


Examples are the liver, brain or kidney, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.
== Detection ==
Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.  


== Sub Heading 2 ==
Classical pointers for end organ damage include:  
Timely detection of end organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients suffering from arterial hypertension ([[/www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/#R2|2]]). Classical indicators of hypertensive end organ damage include the following: vascular and hemorrhagic stroke, retinopathy, coronary heart disease/myocardial infarction and heart failure, proteinuria and renal failure and in the vasculature, atherosclerotic change including the development of stenoses and aneurysms.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref>


* Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
* [[Stroke]], vascular and hemorrhagic
* Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
* Retinopathy
* Similar to arterial hypertension and obesity, type 2 diabetes mellitus is associated with target organ damage
* [[Coronary Artery Disease (CAD)|Coronary heart disease]]/[[Myocardial Infarction|myocardial infarction]] and [[Congestive Heart Failure|heart failure]]
* Proteinuria
* [[Dialysis Case Study|Renal failure]]
* [[Atherosclerosis|Atherosclerotic]] change eg stenoses and aneurysms in the blood vessels.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref>


== Sub Heading 3 ==
== Risk Factors ==
Many and varied and include:


== Resources  ==
# Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
*bulleted list
# [[Obesity]] is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
*x
# [[Diabetes Mellitus Type 2|Type 2 diabetes mellitus]] is associated with target organ damage
or
 
#numbered list
#x


== Viewing ==
Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".{{#ev:youtube|v=WVFbsgg1c_Q}}<ref>MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]</ref>
== References  ==
== References  ==


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Latest revision as of 06:58, 10 May 2024

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton  

Introduction[edit | edit source]

An end organ is the last organ affected in a chain of events, for instance a disease process. Examples are the liver, brain, kidney or heart. These organs are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension causing eg renal failure.

Detection[edit | edit source]

Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.

Classical pointers for end organ damage include:

Risk Factors[edit | edit source]

Many and varied and include:

  1. Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
  2. Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
  3. Type 2 diabetes mellitus is associated with target organ damage

Viewing[edit | edit source]

Watch this 1 mi nute video with information tables regarding "Assessing damage to major organs due to hypertension".

[2]

References[edit | edit source]

  1. Schmieder RE. End organ damage in hypertension. Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)
  2. MediBuddy - Your Health Friend. End organ damage in Hypertension | Hypertension Update | Dr Adrija | CME Session | MediBuddy. Available from: https://www.youtube.com/watch?v=WVFbsgg1c_Q [last accessed 9.5.2024]