Patient-Reported Outcomes Measurement Information System Global Health (PROMIS GH-10)

Original Editor - Melissa Coetsee

Top Contributors - Melissa Coetsee, Lucinda hampton and Cindy John-Chu  

Objective[edit | edit source]

Patient-Reported Outcomes Measurement Information System (PROMIS) is "a set of person-centred measures that evaluates and monitors physical, mental, and social health in adults"[1]. It aims to improve patient-clinician communication and can be used to screen for disability[1]. Self-reported health has also been shown to be predictive of health care utilisation and hospitalisation[2].

The PROMIS Global Health-10 (PROMIS GH-10) is a subset of PROMIS which measures generic health related quality of life.

Domains assessed[1]:

  • Physical Health (physical function, fatigue, pain)
  • Mental Health (emotional distress, social health)

Intended Population[edit | edit source]

PROMIS GH-10 has been intended for use in adults[3] (a paediatric version is also available) in:

Method of Use[edit | edit source]

It consists of a 10-item patient-reported questionnaire. Each question has a five-point scale (ranging from Poor to Excellent). The results are analysed and compared with normal values for the general population. The higher the score the healthier the patient (maximum score =20). It only takes 2-5min to complete which makes it very easy to use in a clinical setting.

Since this is a patient-reported tool, patient cognition and understanding needs to be assessed before using the outcome measure.

Translations: PROMIS has been translated into various different languages using forward and back translation, multiple expert reviews and cognitive debriefing to ensure that the translations are valid[3]. Current freely available languages include: Spanish & English

Evidence[edit | edit source]

As of 2023, it is still a relatively new measure and further studies assessing its validity in a range of settings is still required and underway. It has however been shown to be reliable and valid for use in the general population[4][5] and various other specific conditions:

  • Lower back pain: The International Association of Pain (IASP) recommends the PROMIS GH-10 as a valid measurement tool of quality of life (along with SF-12) in people with chronic low back pain [6][7]. A recent study identified it as one of the core outcome measures that should be used in this population[8].
  • Hip arthroscopy for FAIS: PROMIS GH-10 proved to be inferior to the modified Harris Hip Score and seems to have limited use in this population[9].
  • Knee arthroplasty: PROMIS GH-10 is a valid tool to measure patient outcomes after knee arthroplasty, and correlates with KOOS scores[10]. It also demonstrated superior responsiveness to change when compared to EQ-5D[11].
  • Upper limb: The physical health subscale correlates well with the QuickDASH[12].
  • Stroke: PROMIS GH-10 is recommended for use in assessing the health status of patients after a stroke[13][14]

Links[edit | edit source]

Online version of PROMIS Global 10

Access to the latest version of PROMIS Global 10

References[edit | edit source]

  1. 1.0 1.1 1.2 Hays RD, Schalet BD, Spritzer KL, Cella D. Two-item PROMIS® global physical and mental health scales. Journal of patient-reported outcomes. 2017 Dec;1(1):1-5.
  2. Blumenthal KJ, Chang Y, Ferris TG, Spirt JC, Vogeli C, Wagle N, Metlay JP. Using a self-reported global health measure to identify patients at high risk for future healthcare utilization. Journal of general internal medicine. 2017 Aug;32:877-82.
  3. 3.0 3.1 PROMIS Health Organization. What is PROMIS?. Available from (accessed 22 June 2023)
  4. Barile JP, Reeve BB, Smith AW, Zack MM, Mitchell SA, Kobau R, Cella DF, Luncheon C, Thompson WW. Monitoring population health for Healthy People 2020: evaluation of the NIH PROMIS® Global Health, CDC Healthy Days, and satisfaction with life instruments. Quality of Life Research. 2013 Aug;22:1201-11.
  5. Hays RD, Bjorner JB, Revicki DA, Spritzer KL, Cella D. Development of physical and mental health summary scores from the patient-reported outcomes measurement information system (PROMIS) global items. Quality of life Research. 2009 Sep;18:873-80.
  6. Pak SS, Miller MJ, Cheuy VA. Use of the PROMIS-10 global health in patients with chronic low back pain in outpatient physical therapy: a retrospective cohort study. Journal of patient-reported outcomes. 2021 Dec;5(1):1-0.
  7. IASP. Core Outcome Measures for Low Back Pain. Available from: (accessed 22 June 2023)
  8. Chiarotto A, Boers M, Deyo RA, Buchbinder R, Corbin TP, Costa LO, Foster NE, Grotle M, Koes BW, Kovacs FM, Lin CW. Core outcome measurement instruments for clinical trials in nonspecific low back pain. Pain. 2018 Mar;159(3):481.
  9. Bido J, Sullivan SW, Dooley MS, Nawabi DH, Ranawat AS, Kelly BT, Nwachukwu BU. PROMIS Global-10 poorly correlates with legacy outcomes for patients undergoing hip arthroscopy. Journal of Hip Preservation Surgery. 2021 Jan;8(1):67-74.
  10. Khalil LS, Darrith B, Franovic S, Davis JJ, Weir RM, Banka TR. Patient-reported outcomes measurement information system (PROMIS) global health short forms demonstrate responsiveness in patients undergoing knee arthroplasty. The Journal of Arthroplasty. 2020 Jun 1;35(6):1540-4.
  11. Shim J, Hamilton DF. Comparative responsiveness of the PROMIS-10 Global Health and EQ-5D questionnaires in patients undergoing total knee arthroplasty. The Bone & Joint Journal. 2019 Jul;101(7):832-7.
  12. Stoop N, Menendez ME, Mellema JJ, Ring D. The PROMIS Global Health Questionnaire correlates with the QuickDASH in patients with upper extremity illness. Hand. 2018 Jan;13(1):118-21.
  13. Lam KH, Kwa VI. Validity of the PROMIS-10 Global Health assessed by telephone and on paper in minor stroke and transient ischaemic attack in the Netherlands. BMJ open. 2018 Jul 1;8(7):e019919.
  14. Katzan IL, Lapin B. PROMIS GH (patient-reported outcomes measurement information system Global Health) scale in stroke: a validation study. Stroke. 2018 Jan;49(1):147-54.