Disc Herniation: Difference between revisions

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=== Characteristics/Clinical Presentation ===
=== Characteristics/Clinical Presentation ===
'''Cervical Spine'''
'''History'''
In the cervical spine, the C6-7 is the most common herniation disc that causes symptoms, mostly radiculopathy. History in these patients should include the chief complaint, the onset of symptoms, where the pain starts and radiates. History should include if there are any past treatments.
'''Physical examination'''
On physical examination, particular attention should be given to weaknesses and sensory disturbances, and their myotome and dermatomal distribution. The examiner should also pay attention at this point to any sign of spinal cord dysfunction.
'''Table 1''': Typical findings of solitary nerve lesion due to compression by herniated disc in cervical spine
* '''C5 Nerve''' - neck, shoulder, and scapula pain, lateral arm numbness, and weakness during shoulder abduction, external rotation, elbow flexion, and forearm supination. The reflexes affected are the biceps and brachioradialis.
* '''C6 Nerve''' - neck, shoulder, scapula, and lateral arm, forearm, and hand pain, along with lateral forearm, thumb, and index finger numbness. Weakness during shoulder abduction, external rotation, elbow flexion, and forearm supination and pronation is common. The reflexes affected are the biceps and brachioradialis.
* '''C7 Nerve''' - neck, shoulder, middle finger pain are common, along with the index, middle finger, and palm numbness. Weakness on the elbow and wrist are common, along with weakness during radial extension, forearm pronation, and wrist flexion may occur. The reflex affected is the triceps.
* '''C8 Nerve''' - neck, shoulder, and medial forearm pain, with numbness on the medial forearm and medial hand. Weakness is common during finger extension, wrist (ulnar) extension, distal finger flexion, extension, abduction, and adduction, along with during distal thumb flexion. No reflexes are affected.
* '''T1 Nerve''' - pain is common in the neck, medial arm, and forearm, whereas numbness is common on the anterior arm and medial forearm. Weakness can occur during thumb abduction, distal thumb flexion, and finger abduction and adduction. No reflexes are affected.
Cervical disc herniation Cervical disc herniation causes referred pain to the head, face, neck, arms, shoulders and chest, and even in the low back. In the study of F. W. Gorham they describe how the pain pattern at each level is not consistent<ref>F. W. Gorham; Cervical Disc Injury—Symptoms and Conservative Treatment. Calif Med. 1964 Nov; 101(5): 363–367. PMCID: PMC1515823 Level of evidence: 2A</ref>.   
Cervical disc herniation Cervical disc herniation causes referred pain to the head, face, neck, arms, shoulders and chest, and even in the low back. In the study of F. W. Gorham they describe how the pain pattern at each level is not consistent<ref>F. W. Gorham; Cervical Disc Injury—Symptoms and Conservative Treatment. Calif Med. 1964 Nov; 101(5): 363–367. PMCID: PMC1515823 Level of evidence: 2A</ref>.   



Revision as of 03:05, 25 January 2020

This article is currently under review and may not be up to date. Please come back soon to see the finished work! (25/01/2020)

Original Editors Fauve simoens, Nele Postal

Definition/Description[edit | edit source]

Lumbar disc herniation (LDH) is a common low back disorder. It is one of the most common diseases that produces low back pain and/or leg pain in adults[1]., A herniated disc is a displacement of disc material (nucleus pulposus or annulus fibrosis) beyond the intervertebral disc space[2]. This herniation process begins from failure in the innermost annulus rings and progresses radially outward. The damage to the annulus of the disc appears to be associated with fully flexing the spine for a repeated or prolonged period of time. The nucleus loses its hydrostatic pressure and the annulus bulges outward during disc compression[3]. Other names used to describe this type of pathology are: prolapsed disc, herniated nucleus pulposus and discus protrusion[4][5][6].

  • The management of disc herniation requires an interprofessional team. The initial treatment should be conservative, unless a patient has severe neurological compromise.
  • Surgery is usually the last resort as it does not always result in predictable results. Patients are often left with residual pain and neurological deficits, which are often worse after surgery.
  • Physical therapy is the key for most patients. The outcomes depend on many factors but those who particpate in regular exercise and maintain a healthy body weight have better outcomes than people who are sedentary[7].

Clinically Relevant Anatomy[edit | edit source]

see Lumbar Anatomy for great detail

Intervertebral discs

Two adjacent vertebral bodies are linked by an intervertebral disc. Together with the corresponding facet joints, they form the ‘functional unit of Junghans’n The disc consists of an annulus fibrosus, a nucleus pulposus and two cartilaginous endplates. The distinction between annulus and nucleus can only be made in youth, because the consistency of the disc becomes more uniform in the elderly. For this reason, nuclear disc protrusions are rare after the age of 70. From a clinical point of view, it is important to consider the disc as one integrated unit, the normal function of which depends largely on the integrity of all the elements. That means that damage to one component will create adverse reactions in the others[8].

The disc contain an

Allan foto3.jpg
  • Endplate
  • Annulus fibrosus
  • Nucleus pulposus

Etiology[edit | edit source]

An intervertebral disc is composed of annulus fibrous which is a dense collagenous ring encircling the nucleus pulposus.

  • Disc herniation occurs when part or all the nucleus pulposus protrudes through the annulus fibrous.
  • The most common cause of disc herniation is a degenerative process in which as humans age, the nucleus pulposus becomes less hydrated and weakens. This process will lead to progressive disc herniation that can cause symptoms.
  • The second most common cause of disc herniation is trauma.
  • Other causes include connective tissue disorders and congenital disorders such as short pedicles.
  • Disc herniation is most common in the lumbar spine followed by the cervical spine. A high rate of disc herniation in the lumbar and cervical spine can be explained by an understanding of the biomechanical forces in the flexible part of the spine. The thoracic spine has a lower rate of disc herniation[7].

Pathophysiology[edit | edit source]

The pathophysiology of herniated discs is believed to be a combination of the mechanical compression of the nerve by the bulging nucleus pulposus and the local increase in inflammatory chemokines.[7]

The disc consists of the annulus fibrosus (a complex series of fibrous rings) and the nucleus pulposus (a gelatinous core containing collagen fibers, elastin fibers and a hydrated gel)[9]. The vertebral canal is formed by the vertebral bodies, intervertebral discs and ligaments on the anterior wall and by the vertebral arches and ligaments on the lateral wall. The spinal cord lies in this vertebral canal[10].

A tear can occur within the annulus fibrosus. The material of the nucleus pulposus can track through this tear and into the intervertebral or vertebral foramen to impinge neural structure[10]. A disc herniation can cause mechanical irritation of these structures which in turn can cause pain. This is presented as low back pain with possible radiculopathy if a nerve is affected[11]. The disc can protrude posteriorly and impinge the roots of the lumbar nerves or it can protrude posterolaterally and impinge the descending root[10].

A disc has few blood vessels and some nerves. These nerves are mainly restricted to the outer lamellae of the annulus fibrosus. In the lumbar region, the level at which a disc herniates does not always correlate to the level of nerve root symptoms[9]. When the herniation is in the posterolateral direction the affected nerve root is the one that exits at the level below the disk herniation. This is because the nerve root at the hernia-level has already exited the transverse foramen. A foraminal herniation on the other hand affects the nerve root that is situated at the same level.


There are four types of herniated discs described in Clinical Anatomy and Management of Back Pain (2006)[12]:

Bulging:extension of the disc margin beyond the margins of the adjacent vertebral endplates
Protrusion:the posterior longitudinal ligament remains intact but the nucleus pulposus impinges on the anulus fibrosus
Extrusion:the nuclear material emerges through the annular fibers but the posterior longitudinal ligament remains intact
Sequestration:the nuclear material emerges through the annular fibers and the posterior longitudinal ligament is disrupted. A portion of the nucleus pulposus has protruded into the epidural space

1. Bulging:extension of the disc margin beyond the margins of the adjacent vertebral endplates
2. Protrusion:the posterior longitudinal ligament remains intact but the nucleus pulposus impinges on the anulus fibrosus
3. Extrusion:the nuclear material emerges through the annular fibers but the posterior longitudinal ligament remains intact
4. Sequestration:the nuclear material emerges through the annular fibers and the posterior longitudinal ligament is disrupted. A portion of the nucleus pulposus has protruded into the epidural space

Epidemiology[edit | edit source]

The incidence of herniated disc is about 5 to 20 cases per 1000 adults annually and is most common in people in their third to the fifth decade of life, with a male to female ratio of 2:1.

In 95% of the lumbar disc herniation the L4-L5 and L5-S1 discs are affected[13].

Lumbar disc herniation occurs 15 times more than cervical disc herniation, and is an important cause of lower back pain[14][15].

The prevalence of a symptomatic herniated lumbar disc is about 1% to 3% with the highest prevalence among people aged 30 to 50 years, with a male to female ratio of 2:1.

In individuals aged 25 to 55 years, about 95% of herniated discs occur at the lower lumbar spine (L4/5 and L5/S1 level); disc herniation above this level is more common in people aged over 55 years[16].

Recurrent lumbar disc herniation (rLDH) is a common complication following primary discectomy.

The cervical disc herniation is most affected 8% of the time and most often at level C5-C6 and C6-C7.

Characteristics/Clinical Presentation[edit | edit source]

Cervical Spine

History

In the cervical spine, the C6-7 is the most common herniation disc that causes symptoms, mostly radiculopathy. History in these patients should include the chief complaint, the onset of symptoms, where the pain starts and radiates. History should include if there are any past treatments.

Physical examination

On physical examination, particular attention should be given to weaknesses and sensory disturbances, and their myotome and dermatomal distribution. The examiner should also pay attention at this point to any sign of spinal cord dysfunction.

Table 1: Typical findings of solitary nerve lesion due to compression by herniated disc in cervical spine

  • C5 Nerve - neck, shoulder, and scapula pain, lateral arm numbness, and weakness during shoulder abduction, external rotation, elbow flexion, and forearm supination. The reflexes affected are the biceps and brachioradialis.
  • C6 Nerve - neck, shoulder, scapula, and lateral arm, forearm, and hand pain, along with lateral forearm, thumb, and index finger numbness. Weakness during shoulder abduction, external rotation, elbow flexion, and forearm supination and pronation is common. The reflexes affected are the biceps and brachioradialis.
  • C7 Nerve - neck, shoulder, middle finger pain are common, along with the index, middle finger, and palm numbness. Weakness on the elbow and wrist are common, along with weakness during radial extension, forearm pronation, and wrist flexion may occur. The reflex affected is the triceps.
  • C8 Nerve - neck, shoulder, and medial forearm pain, with numbness on the medial forearm and medial hand. Weakness is common during finger extension, wrist (ulnar) extension, distal finger flexion, extension, abduction, and adduction, along with during distal thumb flexion. No reflexes are affected.
  • T1 Nerve - pain is common in the neck, medial arm, and forearm, whereas numbness is common on the anterior arm and medial forearm. Weakness can occur during thumb abduction, distal thumb flexion, and finger abduction and adduction. No reflexes are affected.

Cervical disc herniation Cervical disc herniation causes referred pain to the head, face, neck, arms, shoulders and chest, and even in the low back. In the study of F. W. Gorham they describe how the pain pattern at each level is not consistent[17].

Fig1: Pain pattern cervical disc herniation

Screen Shot 2017-10-12 at 15.59.19.png

Laxmaiah Manchikanti, MD et al presented how cervical disc herniation radiates pain depending on the level where the herniation took place. The sensory, motor dysfunction and reflex changes as a result of compression of the nerve root of the cervical region is also given[18]. Depending on whether primarily motor or sensory involvement is present, radicular pain is deep, dull, and achy or sharp, burning, and electric. Such radicular pain follows a dermatomal or myotomal pattern into the upper limb. Cervical radicular pain most commonly radiates to the interscapular region, although pain can be referred to the occiput, shoulder, or arm as well. Neck pain does not necessarily accompany radiculopathy and frequently is absent[18].

Table 1: Cervical Disc Herniation Radiation

Nerve Root Pain Distribution Movement
C1/C2 Occipital, eyes Neck flexion/extension
C3 Neck, trapezius Neck lateral flexion
C4 Lower neck, trapezius Shoulder elevation
C5 Neck, shoulder, lateral arm Shoulder abduction
C6 Neck, dorsal lateral arm, thumb Elbow flexion/wrist extension
C7 Neck, dorsal lateral forearm, middle finger Elbow flexion/wrist flexion
C8 Neck, medial forearm, ulnar digits Thumb extension
T1 Ulnar forearm Finger abduction

In a study using provocative discography for symptom mapping, Slipman et al showed that unilateral symptoms were found just as often as bilateral symptoms. Slight variation was noted for referred somatic pain originating from each disc level to the neck, shoulder, and upper thoracic region but with a great amount of overlap. Activities that increase intradiscal pressure (eg, lifting, Valsalva manoeuvre) intensify symptoms. Conversely, lying supine provides relief by decreasing intradiscal pressure. Vibrational stress from driving can also exacerbate discogenic pain. Yates et al showed that vibration and shock loading provided sufficient mechanical injury to exacerbate pre-existing herniation, whereas a flexed posture did not influence the distance of nucleus pulposus tracking[19].

Lumbar disc herniation occur in the lower back, most often between the fourth and fifth lumbar vertebral bodies or between the fifth and the sacrum. Symptoms can affect the lower back, buttocks, thigh, anal/genital region (via the Perineal nerve), and may radiate into the foot and/or toe. The sciatic nerve is the most commonly affected nerve, causing symptoms of sciatica. The femoral nerve can also be affected and cause the patient to experience a numb, tingling feeling throughout one or both legs and even feet or even a burning feeling in the hips and legs. A hernia in the lumbar region often compresses the nerve root exiting at the level below the disk. Thus, a herniation of the L4/5 disc will compress the L5 nerve root[20].

Fig 2: Lumbar Disc Herniation Radiation

Dermatome posterior.png

Dermatome anterior.png

Figure 2 illustrates the clinical features of lumbar intervertebral disc herniation. Straight leg raising or cross straight leg raising and motor examination may be crucial in the assessment of disc herniation[20]. Table 2 shows the diagnostic features for various levels of nerve root involvement. Kamran Sahrakar et al[20] review shows how most lumbar disc herniation (lumbar disc diseases) are preceded by bouts of varying degrees and duration of back pain. In many cases, an inciting event cannot be identified. Pain eventually may radiate into the leg. It may be characterized as less achy, burning, or similar to an electrical shock and is often described as a shooting or stabbing pain. The distribution of the leg pain is somewhat dependent on the level of nerve root irritation. Higher herniation (third or fourth lumbar levels) can radiate into the groin or anterior thigh. Lower radiculopathies (first sacral level) cause pain in the calf and bottom of the foot. Fifth lumbar radiculopathy, which occurs most commonly, causes lateral and anterior thigh and leg pain. Often, accompanying numbness or tingling occurs with a distribution similar to the pain. Accompanying muscle weakness may be unrecognized if the pain is incapacitating. The pain usually improves when the patient is in the supine position with the legs slightly elevated. Patients are more comfortable when changing positions. Short walks can bring relief. Long walks or extended sitting (especially driving) can aggravate the pain[18][20]. It may be more severe with standing or sitting. Along with the leg pain, the patient may experience low back pain.

Table 2 - Lumbar Disc Herniation Radiation

Nerve Root Dermatomal area Myotomal area Reflexive changes
L1 Inguinal region Hip flexors
L2 Anterior mid-thigh Hip flexors
L3 Distal anterior thigh Hip flexors and knee extensors Diminished or absent patellar reflex
L4 Medial lower leg/foot Knee extensors and ankle dorsiflexors Diminished or absent patellar reflex
L5 Lateral leg/foot Hallux extension and ankle plantar flexors Diminished or absent achilles reflex 
S1 Lateral side of foot Ankle plantar flexors and evertors Diminished or absent achilles reflex 

Lateral and medial disc herniation Jung Hwan Lee etal. describes how lateral disc herniation (foraminal and extra foraminal) has clinical characteristics that are different from those of medial disc herniation (central and subarticular), including older age, more frequent radicular pain, and neurologic deficits. This is supposedly because lateral disc herniation mechanically irritates or compresses the exiting nerve root or dorsal root ganglion inside of a narrow canal more directly than medial disc herniation. The lateral group showed significantly larger proportion of patients with radiating leg pain and multiple levels of disc herniations than the medial group. No significant differences were found in terms of gender proportions, duration of pain, pre-treatment NRS, severity of disc herniation, and presence of leg muscles’ weakness. The proportion of patients who underwent surgery was not significantly different between both groups. However, the proportion of patients who accomplished successful pain reduction after treatment was significantly smaller in the lateral than the medial group[21].

Differential Diagnosis[edit | edit source]

  • Discogenic pain [22]: Symptoms mainly include low back pain
  • Myofascial pain[22]: leads to local and/or referred pain, sensory disturbances
  • Spondylosis/spondylolisthesis       
  • Cyst [22]: leads to sensory disturbances, occasionally motor deficits
  • Hematoma[22]: diagnosis can be made by CT-scan
  • Discitis/osteomyelitis
  • Mass lesion/malignancy/neurinomas[22]: difficult to diagnose when tumor is small in size. Symptoms mainly include pain in hip and/or thigh and atrophy of glutei and thigh muscles.
  • Aortic dissection[22]: leads to an aneurysm (of the aortic/iliac/abdominal arterie). Symptoms include low back pain, located leg pain.
  • Epidural abscess: can cause symptoms resembling those associated with radicular pain possibly due to a disc herniation in the lumbarspinal column[23].
  • Tumour: if the sequestered disc is unusually large (rare condition), it is possible to confuse it with a tumour on MRI examination. In this case, surgery will need to be performed to confirm diagnosis[24].
  • Hodgkin’s disease: in the advanced stage it can lead to masses taking up space in the spinal column (although this is very rare), in their turn causing symptoms linked to disc herniation (such as the cauda equina syndrome)[25].
  • Other non-discogenic conditions resulting in sciatica:       
  1. Lumbar nerve root schwannoma
  2. Facet hypertrophy
  3. Pelvic endometriosis
  4. Herpes zoster infection

These conditions all result in compression or inflammation along the course of the sciatic nerve or lumbosacral roots[26]

Diagnostic Procedures[edit | edit source]

Neurological Examination[edit | edit source]

  • Straight Leg Raise Test: The SLR test is a test done during the physical examination. This test is a very accurate predictor of a disc herniation in patients under the age of 35. In patients older than 60 a suppression in the positivity of the tests can be found[27][28].
  • Crossed Lasègue[29]
  • Sensory loss: can be tested with light touch or a pin prick followed by classification on a three-point scale[29][30].
  • Anesthesia linked to dermatomes[29]
  • Muscle weakness[29]: testing of muscle groups and rating them om a five-point scale. Examples: testing of dorsiflexion ankle, hip abductors, flexion knee[30]
  • Knee tendon reflex[29]
  • Achilles tendon reflex[29]
  • Finger-ground distance in centimeter[29]
  • Scoliosis: this is a mechanism developed by patients to avoid pain. In patients with a disc herniation the same scoliosis pattern can be found, starting with a short curve at the lumbosacral region and a long curve in the thoracic or thoracolumbar region in the other direction. The herniation can be found in most cases in the direction of the first curve and on the other side of the accompanying trunk shift. To differentiate between a structural scoliosis and a scoliotic posture, the Adams forward bend test can be used[31]
  • Femoral nerve stretch test: found to be positive if the patient experienced radiating pain[30]

Imaging[edit | edit source]


Imaging can be used to reveal disc herniation[32], note that most disc herniations are asymptomatic:

  • Plain X-rays: don't detect herniated disks, but they may be performed to rule out other causes of back pain, such as an infection, tumor, spinal alignment issues or a broken bone.
  • CT-scan: creates cross-sectional images of your spinal column and the structures around it[33].
  • MRI Scans: can be used to confirm the level of the herniated disc, the location of the herniation within that level (axial and left/right), the morphology of the hernia[34] and finally to see which nerve(s) are affected.
  • Myelogram: A dye is injected into the spinal fluid, and then X-rays are taken. This test can show pressure on your spinal cord or nerves due to multiple herniated disks or other conditions[33].
  • Nerve tests: Electromyograms and nerve conduction studies measure how well electrical impulses are moving along nerve tissue. This can help pinpoint the location of the nerve damage[33].
  • 3T MRM (3-Tesla Magnetic Resonance Myelogram): appropriate imaging technique to diagnose far lateral disc herniations in particular. Preferable to disco-CT because of its non-invasive method[35].
  • Discography and disco-CT: can be used to diagnose intradural lumbar disc herniation (very rare) preoperatively. Leakage of the contrast substance into the intradural space can be seen in the images[36].

Outcome Measures[edit | edit source]

If the disc herniation is symptomatic different outcome measures can be used:

  • Short Form-36 bodily pain (SF-36 BP)
  • Physical function scale (PF scores)
  • Oswestry disability index
  • Roland-Morris disability index
  • VAS-score: one of leg pain and one of back pain[29]
  • North American Spine Society Score for neurologic symptoms[37]
  • McGill pain Questionnaire[29]: this questionnaire looks at the location, intensity, quality and pattern of the pain as well as alleviating and aggrevating factors[38].
  • Sciatica Frequency and Bothersome Index (SFBI)[29]: patients rate their leg pain, numbness/tingling in the leg, foot or groin, weakness in the leg/foot and back/leg pain while sitting and the frequency with which these symptoms occur on a scale of 0 (= not bothersome) to 6 (= extremely bothersome)[39].
  • Prolo scale: measures the functional and economic status of the patient after undergoing surgery according to the surgeon and/or nurse involved in research[29].
  • Maine – Seattle Back Questionnaire: a score between 0 and 12 is given to items concerning the back[40].
  • Numeric Rating Scale: used to rate pain (such as pain in the lower back, sciatic pain…) on a scale from 0 (“no pain”) to 10 (“worst pain imaginable”). Patients are asked to rate their current pain intensity[41].
  • Patient Global Impression of Change (PGIC)[41].

Examination[edit | edit source]

Patients with low back pain and sciatica can have radiculopathy due to lower lumbar disc herniation. The following tests can be used for the examination and to conclude if the radiant pain is caused by disc herniation[37].

See cervical/lumbar radiculopathy for the examination that can be used to assess if the radiant pain is caused by disc herniation.

Physical examination of lumbar radiculopathy due to disc herniation[37]

Straight Leg Raise (SLR)[edit | edit source]

specificity (0,89) and sensitivity (0,52)

Straight Leg Raise video provided by Clinically Relevant

The patient is in supine position and the examiner raises the leg (on the symptomatic side). The knee stays fully extended[42][43]. When the angle at the hip in which the SLR is reached differs in comparison to the other leg, or when pain is produced during the test, the test is considered to be positive[43].

Slump Test[edit | edit source]

Slump test video provided by Clinically Relevant

The sitting patient (with convex back) bends his head forward and stretches his leg out with the toes pointing upward. The purpose is to stretch the neural structures within the vertebral canal and foramen[33].

The SLR (0,52) is less sensitive than the slump test (0,84), but the specificity of the SLR (0,89) was slightly higher than the slump test (0,83)[42].

Lasègue’s Test[edit | edit source]

This is an extension of the SLR[33]: the therapist lowers the leg to an extent of five to ten degrees. Then, the foot is passively dorsiflexed. The test is considered to be positive when the ipsilateral leg pain (sciatica below the knee) occurs upon elevation[37].

Crossed Lasegue test (XSLR)[edit | edit source]

This test is considered to be positive when the pain (sciatica) can be reproduced upon passive extension of the contra-lateral leg.

Scoliosis[edit | edit source]

The therapist is going to evaluate this parameter using visual inspection. Scoliosis might be a potential indicator of lumbar disc herniation. Research has proven that the diagnostic performance of this test is really poor. The sensitivity and specificity are really low[37].

Muscle Weakness or Paresis[edit | edit source]

The examiner measures strength during ankle dorsiflexion or extension of the big toe (without or against resistance).
Dorsal flexion impaired --> L4 radiculopathy
Toe extension impaired --> L5 radiculopathy
If the possible range at the symptomatic side differs from the non-symptomatic side, then the test is considered to be positive[37].

Reflexes[edit | edit source]

Weakness or absence of the Achilles tendon reflex possibly refers to S1 radiculopathy[37]

Forward Flexion Test[edit | edit source]

The purpose is to bend forward in standing position. There is no consensus regarding the criteria that have to be considered in order to determine if the radiant pain is caused by disc herniation. Some studies use limitation of forward flexion as main criteria, while others use back/leg pain as the primary indicator.[37]

Hyperextension Test[edit | edit source]

The patient needs to passively mobilise the trunk over the full range of extension, while the knees stay extended. The test indicates that the radiant pain is caused by disc herniation if the pain deteriorates.[37]

Manual Testing and Sensory Testing[edit | edit source]

Look for hypoaesthesia, hypoalgesia, tingling or numbness[37]. One example of testing: the patient closes his eyes and the examiner strikes the skin bilaterally and simultaneously. The patient is asked if he feels any differences between the left and right side. The test is considered to be positive when there is a dermatomal distribution. Although, the diagnostic performance of sensitivity and specificity is poor.[37]

Medical Management[edit | edit source]

Acute cervical and lumbar radiculopathies due to herniated disc are primarily managed with non-surgical treatments.

  • NSAIDs and physical therapy are the first-line treatment modalities.
  • Translaminar epidural injections and selective nerve root blocks are the second line modalities. These are good modalities for managing disabling pain.
  • Patients who fail conservative treatment or patients with neurological deficits need timely surgical consultation[7].  

Surgical Treatment[edit | edit source]

As always surgical treatment is the last resort.

  • Surgical treatments for a herniated disc include laminectomies with discectomies depending on the cervical or lumbar area.
  • Patients with a herniated disc in the cervical spine can be managed via an anterior approach that requires anterior cervical decompression and fusion. This patient can also be managed with artificial disks replacement.
  • Other alternative surgical approaches to the lumbar spine include a lateral or anterior approach that requires complete discectomy and fusion.[7]

Physical Therapy Management[edit | edit source]

Physical therapy often plays a major role in herniated disc recovery. Physiotherapy does not only offer pain relief and decreases disability [44], but it also contributes to protecting the body to prevent further injury[45]. No evidence has been found for the effectiveness of conservative treatment compared with surgery for treatment of cervical disc herniation[46]. Different studies have shown that a combination of different techniques will form the optimal treatment for a herniated disc. There is contradictory and insufficient evidence with respect to the use of traction, ultrasound and low-level laser therapy[47]. Exercise and ergonomic programs should be considered as very important components of this combined therapy[48].

The physical therapy management for patients with disc herniation can be divided into two main groups: patients with or without surgery. In case of surgery, revalidation programmes start regularly 4-6 weeks post-surgery[49].


Some patients with a herniated disc undergo an operation to reduce their symptoms. After this operation they might follow physiotherapy to support their rehabilitation. A comparison among rehabilitation programmes that start four to six weeks post-surgery with exercises versus no treatment shows that exercise programmes are more effective than no treatment in terms of short-term follow-up for pain. They also investigated the difference between high-intensity exercise programmes and low-intensity exercise programmes. There was low-quality evidence shown that high-intensity exercise programmes are slightly more effective for pain and in terms of functional status in the short term compared with low-intensity exercise programmes. However long-term follow-up results for both pain and functional status showed no significant differences between groups. Research shows no significant differences between supervised exercise programmes and home exercise programmes in terms of short-term pain relief[50].


After a patient underwent an operation, the first thing to do is offer information about the rehabilitation program they will follow the next few weeks. The patients are instructed and accompanied in daily activities such as: coming out of bed, going to the bathroom and clothing. Besides all this the patients have to pay attention on the ergonomics of the back throughout back school[28][49][51][52].

Stretching

There is low-quality evidence found to suggest that adding hyperextension to an intensive exercise programme might not be more effective than intensive exercise alone for functional status or pain outcomes. There were also no clinically relevant or statistically significant differences found in disability and pain between combined strength training and stretching, and strength training alone[50].

Behavioural Graded Activity Programme

A global perceived recovery was better after a standard physiotherapy programme than after a behavioural graded activity programme in the short term, however no differences were noted in the long term[50].

Ultrasound and Shock Wave Therapies

Ultrasound is used to penetrate the tissues and transmitting heat deep into the tissues. The aim of ultrasound is to increase local metabolism and blood circulation, enhance the flexibility of connective tissue, and accelerate tissue regeneration, potentially reducing pain and stiffness, while improving mobility. Shock wave applies vibration at a low frequency to the tissues (10, 50, 100, or 250 Hz). This causes an oscillatory pressure to decrease pain. The available evidence does not support the effectiveness of both therapy strategies for treating a herniated disc[53].

Transcutaneous Electrical Nerve Stimulation (TENS)

TENS uses an electrical current to stimulate the patients muscles. Electrodes on the skin send a tiny electrical current to key points on the nerve pathway. It is generally believed to trigger the release of endorphins, which are the body's natural pain killers and reduce muscle spasms. For this reason, TENS therapy contribute to pain relief and improvement of function and mobility of the lumbosacral spine[54].

Manipulative Treatment

Manipulative treatment on lumbar disc herniation appears to be safe, effective, and it seems to be better than other therapies. However high-quality evidence is needed to be further investigated[55].

Stabilisation Exercises/Core Stability

A strong core is important to the health of the spine. The core (abdominal) muscles help the back muscles support the spine. When your core muscles are weak, it puts extra pressure on your back muscles. So it is important to teach core stabilizing exercises to strengthen your back. It is also very important to train the endurance of these muscles. A core stability program decreases pain level, improves functional status, increases health-related quality of life and static endurance of trunk muscles in lumbar disc herniation patients[56]. Individual high-quality trials found moderate evidence that stabilisation exercises are more effective than no treatment[57].

Traction

The goal of traction is to reduce the effects of gravity on the spine. This technique is often used to relief the patient’s pain in order to facilitate the progression to an exercise program[4]. By gently pulling apart the bones, the intent is to reduce the disc herniation. It can be performed in the cervical or lumbar spine[49]. Lumbar traction may be performed in prone or supine position. When applying this kind of treatment, it is recommended to place the patient in a flexed position as it tends to open the neural foramin and to stretch the posterior elements of the back. To unload the intervertebral disc more effectively it is preferable to let the patient lay in a prone position with a correct amount of lordosis in the lower back. Usually traction will be performed with a force equal to 50% of the patient’s body weight. The total duration of the treatment should be 15 minutes with use of an intermittent force pattern of 20 to 30 seconds on and 10 to 15 seconds off[4].
A recent study has shown that traction therapy has positive effects on pain, disability and SLR on patients with intervertebral disc herniation[58].Also one trial found some additional benefit from adding mechanical traction to medication and electrotherapy[2].

Aquatic Vertical Traction

In patients with low back pain and signs of nerve root compression this method had greater effects on spinal height, the relieving of pain, lowering the centralisation response and lowering the intensity of pain than the assuming of a supine flexing position on land[59].

Hot and Cold Therapies

These offer their own set of benefits, and your physical therapist may alternate between them to get the best results. Your physical therapist may use heat to increase blood flow to the target area. Blood helps heal the area by delivering extra oxygen and nutrients. Blood also removes waste byproducts from muscle spasms[10].

  • Cryotherapy can be used to suppress the metabolism of the tissue after joint surgery, because of the decrease in tissue temperature. This leads to a lessening of pain, edema and postoperative bleeding, and also helps postoperative recovery of range of motion much more rapidly. For patients who underwent one level microendoscopic discectomy for lumbar disc herniation the Icing System CF3000 can be used as it can be used to cool the spine when in a supine position or when lying on the side[60].

Muscle Strengthening

Strong muscles are a great support system for your spine and better handle pain. If core stability is totally regained and fully under control, strength and power can be trained. But only when this is necessary for the patients functioning/activities. This power needs to be avoided during the core stability exercises because of the combination of its two components: force and velocity. This combination forms a higher risk to gain back problems and back pain[47].

Traditional Chinese Medicine for Low Back Pain (TCM)

TCM has been demonstrated to be effective. Reviews have demonstrated that acupressure, acupuncture and cupping can be efficacious in pain and disability for chronic low back pain included disc herniation[4][5]

Spinal Manipulative Therapy and Mobilization

Spinal manipulative therapy (SMT) and mobilization (MOB) leads to short-term pain relief when suffering from acute low back pain. When looking at chronic low back pain, SMT has an effect similar to NSAID[6].

Dynamic Lumbar Stabilization Exercises

Exercises which include techniques such as dynamic abdominal girdle and methods for finding and maintaining neutral lumbar position during daily activities. The emphasis is here placed on the multifidus and the transversus abdominis muscle. The multifidus plays a role in the protection of the lumbar region against involuntary movements and torsion forces as it contributes to spine stabilisation. On the other side the transversus abdominis assists to lumbar stability through increased abdominal pressure by acting like a belt around the abdomen[51].

Example of Protocol for Rehabilitation Following a Lumbar Microdiscectomy

The following program is an example of a protocol for rehabilitation following a lumbar microdiscectomy[51]:

  • Duration of rehabilitation program: 4 weeks
  • Frequency: every day
  • Duration of one session: approximately 60 minutes
  • Treatment: dynamic lumbar stabilization exercises + home exercises
  • Exercises: Prior to the DLS training session patients are provided with instruction or technique to ensure and protect a neutral spine position. During the first 15 minutes of each session stretching of back extensors, hip flexors, hamstrings and Achilles tendon should be performed.
    DLS consists of:
    • Quadratus exercises
    • Abdominal strengthening
    • Bridging with ball
    • Straightening of external abdominal oblique muscle
    • Lifting one leg in crawling position
    • Lifting crossed arms and legs in crawling position
    • Lunges

Home Exercises 

A home exercise programme should be added to the treatment. These should be performed every day.
Modalities: 5 repetitions during the first week up to 10-15 reps in the following weeks

Aerobic Training

A study has been conducted to analyse the effect of an aerobic training program on post-operative patients. One month after the surgery, the patients received a supervised treadmill exercise next to the home exercise program. The treadmill exercise consisted of a walk of 30 minutes on the treadmill without inclination five times a week with tolerated speed during four weeks. The speed of walking was increased once the patient’s tolerance was considered as high enough. The conclusion is that aerobic exercise-based rehabilitation program in combination with home exercises starting one month after first-time single-level lumbar microdiscectomy has a positive effect on functionality than only a home exercise program. However the authors of the study point out that more studies should be conducted concerning aerobic exercise programs in post-operative patients[61].

Lumbar Tender Point Deep Massage

When used in combination with lumbar traction, this method resulted in a higher pain threshold, less muscle hardness and less intense pain in patients with chronic non-specific lower back pain than lumbar traction on its own[62].

Conservative therapy for cervical spine [63]  According to the systematic review of Gross A.:

  • Cervical manipulation VS inactive control (subacute- chronic): gives immediate pain relief but not on short term follow-up.
  • Cervical manipulation VS cervical mobilization (acute- chronic): decline in pain, better QoL and GPE
  • Cervical manipulation VS medication: (acute- subacute): better function of neck, more decline in pain
  • Cervical manipulation Vs massage (chronic): decline in pain, better function

This concludes that cervical manipulation may give better results in decline in pain and better function than inactive control, cervical mobilization, medication and massage.

The systematic review Bronfort did on spinal manipulative therapy (SMT)concluded that for chronic neck pain that SMT and mobilization may give more pain reduction then a general practitioner management on short term follow-up but similar pain relief like high-technology rehabilitative exercise in the short and long term. In a mix of acute and chronic patients there is limited evidence that SMT, in both the short and long term, is inferior to physical therapy[64].

Clinical Bottom line[edit | edit source]

Intervertebral disc herniation is one of most common diseases that produces low back pain and/or leg pain in adults. It often occurs as a result of age-related degeneration of the annulus fibrosis. Disc herniation are most of the time asymptomatic and 75% of the intervertebral disc herniation recover spontaneously within 6 months.

Disc herniation can occur at different levels in the spine. A herniated disc affects most commonly the lumbar discs between vertebra L4-L5 and L5-S1. Cervical disc herniation are more rare than lumbar disc degeneration. The cervical disc herniation is most locate at level C5-C6 and C6-C7.

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