Total Knee Arthroplasty

Welcome to Vrije Universiteit Brussel's Evidence-based Practice project. This space was created by and for the students in the Rehabilitation Sciences and Physiotherapy program of the Vrije Universiteit Brussel, Brussels, Belgium. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Search Strategy[edit | edit source]

Medical databases: Pubmed, PEDro, Web of Science
Keywords searched: Total knee arthroplasty, knee osteoarthritis, rehabilitation AND TKA, the knee joint, etiology AND TKA, total knee replacement,...
Books: Total Knee Arthroplasty. A Guide to Get Better Performance. Johan Bellemans, Michael D Ries, Jan MK Victor.

Definition/Description[edit | edit source]

add text here

Clinically Relevant Anatomy[edit | edit source]

The Knee is a hinge joint (articulatio gynglymus). This type of joint permits motion in only one plane. The knee is a special hinge joint, because it's biggest motion is flexion-extension, but rotation is also possible in the knee. There are three bones that form the knee joint: the upper part of the Tibia, the lower part of the femur and the patella. The bones are covered with a thin layer of cartilage, which makes sure that there is no friction between the bones and it's also a kind of shock absorber. Both the lateral and medial side of the knee, there is a meniscus, which keeps the tibia to the femur, but which is also a shock absorber. The three bones are kept together by ligaments and are surrounded by a capsule.

Epidemiology /Etiology[edit | edit source]

When all the compartments of the knee are damaged, and the individual is seriously impaired a total knee prosthesis can be necessary. The main reason for a total knee prosthesis is osteoarthritis.[1] (evidence level: 1b)  Because of osteoarthritis, the cartilage of the joint get's damaged and isn't able to absorb shocks anymore. There are a lot of external risk factors that can cause knee osteoarthritis. For example: overweight, previous knee injuries, the (partial) removal of a meniscus,...[2] (evidence level: 2a) Other causes could be rheumatoid arthritis, fractures, or congenital factors. There might also be some genetic factors in the arise of osteoarthritis, but more research is necessary. (evidence level: 2b)
Total knee arthroplasty is mostly performed on women and the frequency of this intervention increases with age.[2]

Characteristics/Clinical Presentation[edit | edit source]

add text here

Differential Diagnosis[edit | edit source]

Osteoarthritis:
Osteoarthritis is a degenerative process at the level of the cartilage and should be well distinguished from arthritis, where it’s about a synovial inflammatory process. Osteoarthritis is the main cause for a total knee arthroplasty.[1] (evidence level: 1b)

Other differential diagnosis:
Rheumatoid arthritis, previous injuries of the knee like the (partial) removal of the meniscus, too much varus of valgus of the knee,...

Diagnostic Procedures[edit | edit source]

add text here related to medical diagnostic procedures

Outcome Measures[edit | edit source]

- Knee disability and Osteoarthritis Outcome score (KOOS) to see if there are any difficulties in the execution of daily activities.

- The Timed Get Up and Go Test (TUG) to see whether the patient is able to walk independently after the surgery or if he needs a walking aid.

- Visual Analogue Scale (VAS) to have an idea about the degree of pain the patient is going through.


(also see Outcome Measures Database)

Examination[edit | edit source]

add text here related to physical examination and assessment

Medical Management
[edit | edit source]

add text here

Physical Therapy Management
[edit | edit source]

add text here

Key Research[edit | edit source]

add links and reviews of high quality evidence here (case studies should be added on new pages using the case study template)

Resources
[edit | edit source]

add appropriate resources here

Clinical Bottom Line[edit | edit source]

add text here

Recent Related Research (from Pubmed)[edit | edit source]

see tutorial on Adding PubMed Feed

Extension:RSS -- Error: Not a valid URL: Feed goes here!!|charset=UTF-8|short|max=10

References[edit | edit source]

see adding references tutorial.

  1. 1.0 1.1 Skou, Søren T., et al. "A randomized, controlled trial of total knee replacement." New England Journal of Medicine 373.17 (2015): 1597-1606.
  2. 2.0 2.1 Blagojevic, M., et al. "Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis." Osteoarthritis and cartilage 18.1 (2010): 24-33.