Long COVID: Difference between revisions

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* Long term consequences of COVID-19 which usually presents with clusters of symptoms, often overlapping, which can fluctuate and change over time and can affect any system in the body for more than 12 weeks.
* Long term consequences of COVID-19 which usually presents with clusters of symptoms, often overlapping, which can fluctuate and change over time and can affect any system in the body for more than 12 weeks.


The long term sequelae of COVID-19 awaits consensus definition, and a variety of nomenclature has been used to describe the long term signs and symptoms of COVID-19. This includes the patient directed terms "Long Covid" <ref name=":0">https://blogs.bmj.com/bmj/2020/10/01/why-we-need-to-keep-using-the-patient-made-term-long-covid/</ref><ref>https://www.sciencedirect.com/science/article/pii/S0277953620306456</ref><ref>https://www.nature.com/articles/d41586-020-02796-2</ref>, "Long Haul Covid" and "Long Haulers", plus other terms including "Post-COVID-19 syndrome" <ref name=":1" /><ref>https://openres.ersjournals.com/content/6/4/00542-2020</ref>, "Post-COVID Syndrome" <ref>https://www.england.nhs.uk/coronavirus/publication/national-guidance-for-post-covid-syndrome-assessment-clinics/</ref>, "Post-Acute COVID-19" <ref>https://www.bmj.com/content/370/bmj.m3026</ref>, and "Post-Acute COVID-19 syndrome"<ref>https://www.england.nhs.uk/coronavirus/publication/national-guidance-for-post-covid-syndrome-assessment-clinics/</ref>. For the purposes of consistency, this page will refer to the long term consequences of COVID-19 as "'''''Long Covid'''''" and to "'''''People Living with COVID-19'''''". We will refer to "Long Covid" because this term acknowledges that cause and disease course are as yet unknown, makes clear that “mild” COVID-19 is not necessarily mild, avoids “chronic,” “post” and “syndrome” that may delegitimise peoples experiences, draws attention to morbidity, and centres people with disability <ref name=":0" />. We will refer to "People Living with COVID-19" to align with existing person first language <ref>https://evidence.nihr.ac.uk/themedreview/living-with-covid19/</ref> and applying knowledge from other health care conditions with experiences of stigma <ref>https://www.nhivna.org/file/5dcbdcb83254e/BP-19-2.pdf</ref>.     
The long term sequelae of COVID-19 awaits consensus definition, and a variety of nomenclature has been used to describe the long term signs and symptoms of COVID-19. This includes the patient directed terms "Long Covid" <ref name=":0">https://blogs.bmj.com/bmj/2020/10/01/why-we-need-to-keep-using-the-patient-made-term-long-covid/</ref><ref name=":2">https://www.sciencedirect.com/science/article/pii/S0277953620306456</ref><ref>https://www.nature.com/articles/d41586-020-02796-2</ref><ref>https://www.bmj.com/content/371/bmj.m4938</ref><ref>https://www.ons.gov.uk/news/statementsandletters/theprevalenceoflongcovidsymptomsandcovid19complications</ref><ref>https://www.nature.com/articles/d41586-020-02796-2</ref>, "Long-Haul Covid" <ref name=":2" /><ref>https://n.neurology.org/content/95/13/559.long</ref> and "Long Haulers" <ref>https://www.nature.com/articles/d41586-020-02598-6</ref><ref>https://onlinelibrary.wiley.com/doi/10.1002/jmv.26624</ref>, plus other terms including "Post-COVID-19 syndrome" <ref name=":1" /><ref>https://openres.ersjournals.com/content/6/4/00542-2020</ref>, "Post-COVID Syndrome" <ref>https://www.england.nhs.uk/coronavirus/publication/national-guidance-for-post-covid-syndrome-assessment-clinics/</ref>, "Post-Acute COVID-19" <ref>https://www.bmj.com/content/370/bmj.m3026</ref>, and "Post-Acute COVID-19 syndrome"<ref>https://www.england.nhs.uk/coronavirus/publication/national-guidance-for-post-covid-syndrome-assessment-clinics/</ref>. For the purposes of consistency, this page will refer to the long term consequences of COVID-19 as "'''''Long Covid'''''" and to "'''''People Living with COVID-19'''''". We will refer to "Long Covid" because this term acknowledges that disease cause and course are as yet unknown, makes clear that “mild” COVID-19 is not necessarily mild, avoids “chronic,” “post” and “syndrome” that may delegitimise peoples experiences, draws attention to morbidity, and centres people with disability <ref name=":0" />. We will refer to "People Living with COVID-19" to align with existing person first language <ref>https://evidence.nihr.ac.uk/themedreview/living-with-covid19/</ref> and applying knowledge from other health care conditions with experiences of stigma <ref>https://www.nhivna.org/file/5dcbdcb83254e/BP-19-2.pdf</ref>.     
 
== What is Long Covid? ==


== Mechanism of Injury / Pathological Process  ==
== Mechanism of Injury / Pathological Process  ==

Revision as of 14:49, 1 January 2021

Original Editor - Darren Brown
Top Contributors - Darren Brown, Jess Bell, Olajumoke Ogunleye, Kim Jackson, Shwe Shwe U Marma, Robin Tacchetti, Tarina van der Stockt, Lucinda hampton, Candace Goh and Chelsea Mclene

Introduction[edit | edit source]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease (COVID-19) [1]. The effects of COVID-19 have been characterised across different time points, defined as [2]:

  • Acute COVID-19 infection with signs and symptoms of COVID-19 for up to 4 weeks.
  • Ongoing symptomatic COVID-19 with signs and symptoms of COVID-19 from 4 weeks up to 12 weeks.
  • Long term consequences of COVID-19 which usually presents with clusters of symptoms, often overlapping, which can fluctuate and change over time and can affect any system in the body for more than 12 weeks.

The long term sequelae of COVID-19 awaits consensus definition, and a variety of nomenclature has been used to describe the long term signs and symptoms of COVID-19. This includes the patient directed terms "Long Covid" [3][4][5][6][7][8], "Long-Haul Covid" [4][9] and "Long Haulers" [10][11], plus other terms including "Post-COVID-19 syndrome" [2][12], "Post-COVID Syndrome" [13], "Post-Acute COVID-19" [14], and "Post-Acute COVID-19 syndrome"[15]. For the purposes of consistency, this page will refer to the long term consequences of COVID-19 as "Long Covid" and to "People Living with COVID-19". We will refer to "Long Covid" because this term acknowledges that disease cause and course are as yet unknown, makes clear that “mild” COVID-19 is not necessarily mild, avoids “chronic,” “post” and “syndrome” that may delegitimise peoples experiences, draws attention to morbidity, and centres people with disability [3]. We will refer to "People Living with COVID-19" to align with existing person first language [16] and applying knowledge from other health care conditions with experiences of stigma [17].

What is Long Covid?[edit | edit source]

Mechanism of Injury / Pathological Process[edit | edit source]

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Clinical Presentation[edit | edit source]

add text here relating to the clinical presentation of the condition

Diagnostic Procedures[edit | edit source]

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Outcome Measures[edit | edit source]

add links to outcome measures here (see Outcome Measures Database)

Management / Interventions[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Resources[edit | edit source]

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References[edit | edit source]

  1. ↑ https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it
  2. ↑ 2.0 2.1 https://www.nice.org.uk/guidance/gid-ng10179/documents/final-scope
  3. ↑ 3.0 3.1 https://blogs.bmj.com/bmj/2020/10/01/why-we-need-to-keep-using-the-patient-made-term-long-covid/
  4. ↑ 4.0 4.1 https://www.sciencedirect.com/science/article/pii/S0277953620306456
  5. ↑ https://www.nature.com/articles/d41586-020-02796-2
  6. ↑ https://www.bmj.com/content/371/bmj.m4938
  7. ↑ https://www.ons.gov.uk/news/statementsandletters/theprevalenceoflongcovidsymptomsandcovid19complications
  8. ↑ https://www.nature.com/articles/d41586-020-02796-2
  9. ↑ https://n.neurology.org/content/95/13/559.long
  10. ↑ https://www.nature.com/articles/d41586-020-02598-6
  11. ↑ https://onlinelibrary.wiley.com/doi/10.1002/jmv.26624
  12. ↑ https://openres.ersjournals.com/content/6/4/00542-2020
  13. ↑ https://www.england.nhs.uk/coronavirus/publication/national-guidance-for-post-covid-syndrome-assessment-clinics/
  14. ↑ https://www.bmj.com/content/370/bmj.m3026
  15. ↑ https://www.england.nhs.uk/coronavirus/publication/national-guidance-for-post-covid-syndrome-assessment-clinics/
  16. ↑ https://evidence.nihr.ac.uk/themedreview/living-with-covid19/
  17. ↑ https://www.nhivna.org/file/5dcbdcb83254e/BP-19-2.pdf

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