Healthy Aging with Traumatic Brain Injury: Difference between revisions

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== Effects of Increasing Age with TBI ==
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== Effects on Cognition ==
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People who have had moderate or severe TBI are known to have an increased risk of decline of cognitive abilities, and increased risk of dementia, later in life. One 2015 study<ref name=":0">Cole JH, Leech R, Sharp DJ.


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Prediction of brain age suggests accelerated atrophy after traumatic brain injury.
 
Annals of Neurology, Vol 77, Issue 4.
</ref> compared MRI brain scans of people with TBI to a control group; they developed a computer program with an algorithm to estimate the person't "brain age", and the people with TBI were found to have a brain age on average 5 years older than the control group. The authors note: "There was also a correlation between time since injury and predicted age difference, suggesting that these changes in brain structure do not occur during the injury itself, but result from ongoing biological processes, potentially similar to those seen in normal ageing, that progress more quickly after an injury."
 
This suggests that after TBI there may be secondary process which lead to increasing brain damage for years afterwards<ref name=":0" />.
 
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Revision as of 09:41, 18 August 2019

Welcome to Traumatic Brain Injury Content Creation Project. This page is being developed by participants of a project to populate the Traumatic Brain Injury Section of Physiopedia. 
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Effects of Increasing Age with TBI[edit | edit source]

Effects on Cognition[edit | edit source]

People who have had moderate or severe TBI are known to have an increased risk of decline of cognitive abilities, and increased risk of dementia, later in life. One 2015 study[1] compared MRI brain scans of people with TBI to a control group; they developed a computer program with an algorithm to estimate the person't "brain age", and the people with TBI were found to have a brain age on average 5 years older than the control group. The authors note: "There was also a correlation between time since injury and predicted age difference, suggesting that these changes in brain structure do not occur during the injury itself, but result from ongoing biological processes, potentially similar to those seen in normal ageing, that progress more quickly after an injury."

This suggests that after TBI there may be secondary process which lead to increasing brain damage for years afterwards[1].

Sub Heading 3[edit | edit source]

Add text here...

References[edit | edit source]

  1. 1.0 1.1 Cole JH, Leech R, Sharp DJ. Prediction of brain age suggests accelerated atrophy after traumatic brain injury. Annals of Neurology, Vol 77, Issue 4.