Fat Pad Syndrome

Anatomy and Biomechanics[edit | edit source]

Infrapatellar fat pad has been considered as a source of anterior knee pain. A differentiated diagnosis came later as symptoms and diagnostic modalities showed clear evidence of a distinctive pathology yielding practical application to its management. 

The infrapatellar fat pad is an intra-articular extra synovial structure occupying the whole anterior part of the knee joint in all joint positions[1].

Boundaries:

  • Superiorly by the inferior pole of the patella,
  • Inferiorly by the anterior tibia, intermeniscal ligament, meniscal horns and infrapatellar bursa,
  • Anteriorly by the patellar tendon
  • Posteriorly by the femoral condyles and intercondylar notch

Attachments:

  • The intercondylar notch via the ligamentum mucosum,
  • Anterior horns of the menisci
  • The proximal end of the patella tendon
  • The inferior pole of the patella

Supplied mainly by the posterior tibial nerve. The infrapatellar fat pad can be a source of both localized and sever pain this could be attributed to the presence of type VIa nerve endings[2] which could be activated through mechanical deformation or chemical pain mediators.  Substance P-nerve fibers is also present in individuals with anterior knee pain, particularly when the infrapatellar fat pad is inflamed[3]. As a potential source of inflammation and pain, some authors considered the fat pad to be a key structure in patellar tendinopathy[4] and osteoarthritis[5].

Numerous studies investigated the influence of the fat pad on knee mechanics. Earlier studies reported fat pad to be a lubricant structure that facilitated the flow of synovial fluid inside the joint[1]. Later, it became clear that the role of the fat pad yields more sophisticated functions due to the complex neurovascular supply of the structure. A study showed reduced coordination between medial and lateral vastus muscle motor units in anterior knee pain[6]. Another reported a a significantly later activation and reduced amplitude of contraction of quadriceps during stair stepping following injecting the fat pad with a painful hypertonic saline[7]. The inhibited fat pad resulted in increased patellofemoral loading and reduced quadricpes activation[1]. However, the exact association of fat pad and knee biomechanics needs further investigations.

Diagnosis[edit | edit source]

Metabolic Role of the Infrapatellar Fat Pad[edit | edit source]

Acute Fat Pad Syndrome[edit | edit source]

Chronic Fat Pad Syndrome[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 Mr James MA, Bhatti W, ANAND MS. Infrapatellar fat pad syndrome: a review of anatomy, function, treatment and dynamics. Acta Orthopaedica Belgica. 2016;82:1-2016.
  2. Bohnsack M, Wilharm A, Hurschler C, Rühmann O, Stukenborg-Colsman C, Joachim Wirth C. Biomechanical and kinematic influences of a total infrapatellar fat pad resection on the knee. The American journal of sports medicine. 2004 Dec;32(8):1873-80.
  3. Bohnsack M, Meier F, Walter GF, Hurschler C, Schmolke S, Wirth CJ, Rühmann O. Distribution of substance-P nerves inside the infrapatellar fat pad and the adjacent synovial tissue: a neurohistological approach to anterior knee pain syndrome. Archives of orthopaedic and trauma surgery. 2005 Nov 1;125(9):592-7.
  4. Culvenor AG, Cook JL, Warden SJ, Crossley KM. Infrapatellar fat pad size, but not patellar alignment, is associated with patellar tendinopathy. Scandinavian journal of medicine & science in sports. 2011 Dec;21(6):e405-11.
  5. Clockaerts S, Bastiaansen-Jenniskens YM, Runhaar J, Van Osch GJ, Van Offel JF, Verhaar JA, De Clerck LS, Somville J. The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review. Osteoarthritis and Cartilage. 2010 Jul 1;18(7):876-82.
  6. Mellor R, Hodges PW. Motor unit syncronization is reduced in anterior knee pain. The Journal of pain. 2005 Aug 1;6(8):550-8.
  7. Hodges PW, Mellor R, Crossley K, Bennell K. Pain induced by injection of hypertonic saline into the infrapatellar fat pad and effect on coordination of the quadriceps muscles. Arthritis Care & Research. 2009 Jan 15;61(1):70-7.