Sarcomere: Difference between revisions

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== Introduction ==
== Introduction ==
[[File:Sarcomere.gif|thumb|374x374px|Thick myosin filaments; thinner actin filaments]]
[[File:Sarcomere.gif|thumb|374x374px|Thick myosin filaments; thinner actin filaments]]
A sarcomere is the basic contractile unit of myocyte (muscle fibre). A sarcomere is composed of two main protein filaments. thin actin and thick myosin filaments,  together being the active structures responsible for muscular contraction. The widely accepted theory describing muscular contraction is called the sliding filament theory, which proposes that the active force is generated as actin filaments slide past the myosin filaments, resulting in contraction of an individual sarcomere<ref>Mansfield PJ, Neumann DA. Essentials of kinesiology for the physical therapist assistant e-book. Elsevier Health Sciences; 2018 Oct 23.Available:https://www.sciencedirect.com/book/9780323544986/essentials-of-kinesiology-for-the-physical-therapist-assistant (accessed 10.7.2022)</ref>.
A sarcomere is the basic contractile unit of [[Muscle Cells (Myocyte)|myocyte]] (muscle fibre). A sarcomere is composed of two main [[Proteins|protein]] filaments (thin actin and thick myosin filaments) which are the active structures responsible for muscular contraction. The widely accepted theory describing muscular contraction is called the sliding filament theory, which proposes that the active force is generated as actin filaments slide past the myosin filaments, resulting in contraction of an individual sarcomere<ref>Mansfield PJ, Neumann DA. Essentials of kinesiology for the physical therapist assistant e-book. Elsevier Health Sciences; 2018 Oct 23.Available:https://www.sciencedirect.com/book/9780323544986/essentials-of-kinesiology-for-the-physical-therapist-assistant (accessed 10.7.2022)</ref>.


== Sliding Filament Theory ==
== Sliding Filament Theory ==
[[File:Sarcomere zones.png|thumb|464x464px|Muscle contraction based on sliding filament theory]]
[[File:Sarcomere zones.png|thumb|464x464px|Muscle contraction based on sliding filament theory]]
The sliding theory, proposed by scientists, who through the  by the use of high-resolution microscope visualised  actin and myosin filaments within a sarcomere. They could see length of the sarcomere when relaxed and its shortening as it contracted, and were able to give names to particular zones.
The sliding theory, proposed by scientists, who through the use of high-resolution microscopes visualised  the actin and myosin filaments within a sarcomere. They could see length of the sarcomere when relaxed and its shortening as it contracted, and were able to give names to particular zones.


* A bands (or anisotropic bands): It is also called the dark band and contains the whole thick filament (myosin).
* A bands (or anisotropic bands): It is also called the dark band and contains the whole thick filament (myosin).

Revision as of 09:35, 10 July 2022

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton and Vidya Acharya  

Introduction[edit | edit source]

Thick myosin filaments; thinner actin filaments

A sarcomere is the basic contractile unit of myocyte (muscle fibre). A sarcomere is composed of two main protein filaments (thin actin and thick myosin filaments) which are the active structures responsible for muscular contraction. The widely accepted theory describing muscular contraction is called the sliding filament theory, which proposes that the active force is generated as actin filaments slide past the myosin filaments, resulting in contraction of an individual sarcomere[1].

Sliding Filament Theory[edit | edit source]

Muscle contraction based on sliding filament theory

The sliding theory, proposed by scientists, who through the use of high-resolution microscopes visualised the actin and myosin filaments within a sarcomere. They could see length of the sarcomere when relaxed and its shortening as it contracted, and were able to give names to particular zones.

  • A bands (or anisotropic bands): It is also called the dark band and contains the whole thick filament (myosin).
  • I bands (or isotropic bands): it is called the light band that contains only the thin filament (actin). The thin filament lies between the two thick filaments.
  • Z disc: it is the area where two actin filaments connect and transverse the I bands. Similarly, sarcomere can also be described as the structure between the two z discs.
  • M line: M line contains the protein called myomesin and it marks the centre of the sarcomere.
  • H zone: it is the area between the M line and Z disc and this zone contains only the myosin[2].

Sub Heading 3[edit | edit source]

Resources[edit | edit source]

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References[edit | edit source]

  1. Mansfield PJ, Neumann DA. Essentials of kinesiology for the physical therapist assistant e-book. Elsevier Health Sciences; 2018 Oct 23.Available:https://www.sciencedirect.com/book/9780323544986/essentials-of-kinesiology-for-the-physical-therapist-assistant (accessed 10.7.2022)
  2. The biology notes Sarcomere Available:https://thebiologynotes.com/sarcomere/ (accessed 10.7.2022)