The Physiotherapy Management of Thalassaemia and Sickle Cell Anaemia
Original Editors - Mariam Hashem
Top Contributors - Mariam Hashem, Tarina van der Stockt, Kim Jackson, Lucinda hampton, Jess Bell, Aminat Abolade and Stacy Schiurring
Thalassaemia[edit | edit source]
Thalassaemia is one of the most common inherited diseases worldwide. It is defined as an autosomal recessive blood disorder that results from reduction or absence in the production of globin chains that make up the haemoglobin (Hb) leading to abnormal destruction of erythrocytes and consequently decreased oxygen delivery[1].
Thalassemia is derived from the Greek word "Thalassa" which means ''sea''. It's also referred to as ''Mediterranean Anaemia''. It mainly affects individuals originating from the Mediterranean area, Middle East, Transcaucasia, Central Asia, Indian subcontinent, and Southeast Asia[2].
There are two types of Thalassaemia: α- and β- and complex thalassemias depending on the type of the involved globin chain. The incidence rate is about 4.4 of every 10000 live births globally and approximately about 5% of all population[2].
It has been estimated that the globally there are 9million carriers of Thalassaemia and Sickle cell anaemia become pregnant each year[3].
Sickle Cell Anaemia[edit | edit source]
References[edit | edit source]
- ↑ Cao A, Kan YW. The prevention of thalassemia. Cold Spring Harbor perspectives in medicine. 2013 Feb 1;3(2):a011775.
- ↑ 2.0 2.1 Kora A. The Physiotherapy Management of Thalassaemia and Sickle Cell Anaemia. Physioplus Course 2020
- ↑ Modell B, Darlison M. Global epidemiology of haemoglobin disorders and derived service indicators. Bulletin of the World Health Organization. 2008;86:480-7.
