Malignant Melanoma
Original Editors - Emily Erwin & Brooke Sowards from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Top Contributors - Emily Erwin, Brooke Sowards, Ellen Hosking, Lucinda hampton, Elaine Lonnemann, Kim Jackson, Vidya Acharya, 127.0.0.1, Wendy Walker, Calli Paydo and WikiSysop
Definition/Description[edit | edit source]
Malignant Melanoma is a cancer that begins in a specific type of skin cells known as melanocytes. This type of cancer may also be known as melanoma or cutaneous melanoma.
Melanocytes are located in the most superficial layer of skin, the epidermis. The epidermis protects the underlying dermis and subcutaneous tissue layers of the skin. Melanocytes are found in the basal layer, or the lowest layer, of the epidermis. These cells produce a brown pigment known as melanin, which gives the skin its tan appearance. After sun exposure, additional melanin is produced, resulting in a darkening or "tanning" of the skin. Melanin also plays an integral role in preventing skin damage from the sun's harmful rays. [1]
Malignant growths may occur following damage to skin cell DNA. If unrepaired, this damage initiates mutations that result in rapid proliferation of skin cells that form malignant tumors. [2]
Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports/ Case Studies[edit | edit source]
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Resources
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