Therapeutic Exercise Prescription: Epigenetic and Healthy Ageing
Original Editor - Tolulope Adeniji
Top Contributors - Tolulope Adeniji, Lucinda hampton and Kim Jackson
Overview[edit | edit source]
Ageing is a phyisological declines in body systems and it is complex and intra-individual process. The hallmarks of ageing is recently noted to include about nine cellullar and molecular characteristics including epigenetic alterations; genomic instability; telomeric attrition; loss of proteostasis; and deregulated nutrient sensing. Others are mitochondrial dysfunction; cellular senescence; stem cell exhaustion; and altered intercellular communication. Exercise therapy had been shown to improve all these nine domains. Therefore prescribing exact amount of exercise that will give us desire effect in achieving health domain is essential.
