Calcium Channel Blockers: Difference between revisions

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== Introduction ==
== Introduction ==
[[File:Calcium channel blocker.png|thumb|Calcium channel blocker]]
[[File:Calcium channel blocker.png|thumb|Ethanol blocks voltage-gated CC|alt=]]
Calcium channel blockers are used in the management of [[hypertension]], [[Angina|angina pectoris]], supraventricular [[Heart Arrhythmias|arrhythmias]], [[Subarachnoid Hemorrhage (SAH)|subarachnoid hemorrhage]], [[Pulmonary Hypertension|pulmonary hypertension]], and for the prevention of [[Migraine Headache|migraine]]<ref>Gad SC. Phthalic Anhydride. Encyclopedia of Toxicology (Third Edition). 2014 Jan 1:934-6. Available:https://www.sciencedirect.com/topics/neuroscience/calcium-channel-blockers (accessed 29.3.2022)</ref>.
[[File:CCB.jpeg|thumb|CCB in a cell membrane.]]
Calcium channel blockers (CCBs) are used in the management of [[hypertension]], [[Angina|angina pectoris]], supraventricular [[Heart Arrhythmias|arrhythmias]], [[Subarachnoid Hemorrhage (SAH)|subarachnoid hemorrhage]], [[Pulmonary Hypertension|pulmonary hypertension]], and for the prevention of [[Migraine Headache|migraine]]<ref>Gad SC. Phthalic Anhydride. Encyclopedia of Toxicology (Third Edition). 2014 Jan 1:934-6. Available:https://www.sciencedirect.com/topics/neuroscience/calcium-channel-blockers (accessed 29.3.2022)</ref>.


They work by preventing calcium from entering the cells of the [[Muscle: Cardiac|heart]] and arteries. Calcium causes the heart and [[arteries]] to contract more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax and open.
They work by preventing calcium from entering the cells of the [[Muscle: Cardiac|heart]] and arteries. Calcium causes the heart and [[arteries]] to contract more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax and open.

Revision as of 01:35, 30 March 2022

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton, Wajeeha Hassan and Kim Jackson  

Introduction[edit | edit source]

Ethanol blocks voltage-gated CC
CCB in a cell membrane.

Calcium channel blockers (CCBs) are used in the management of hypertension, angina pectoris, supraventricular arrhythmias, subarachnoid hemorrhage, pulmonary hypertension, and for the prevention of migraine[1].

They work by preventing calcium from entering the cells of the heart and arteries. Calcium causes the heart and arteries to contract more strongly. By blocking calcium, calcium channel blockers allow blood vessels to relax and open.

Some calcium channel blockers can also slow the heart rate, which can further lower blood pressure[2].

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Resources[edit | edit source]

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References[edit | edit source]

  1. Gad SC. Phthalic Anhydride. Encyclopedia of Toxicology (Third Edition). 2014 Jan 1:934-6. Available:https://www.sciencedirect.com/topics/neuroscience/calcium-channel-blockers (accessed 29.3.2022)
  2. Mayo clinic CCBs Available:https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/calcium-channel-blockers/art-20047605 (accessed 29.3.2022)