Parkinsonism: Difference between revisions
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Following are descriptions of some of the most common Parkinsonism disorders. Remember many people will not exhibit the cardinal symptoms necessary for a diagnosis of a specific disorder and will simply be labeled “parkinsonism”. For these people a definite diagnosis will only come if the family requests a brain autopsy at time of death<ref name=":0" />. | Following are descriptions of some of the most common Parkinsonism disorders. Remember many people will not exhibit the cardinal symptoms necessary for a diagnosis of a specific disorder and will simply be labeled “parkinsonism”. For these people a definite diagnosis will only come if the family requests a brain autopsy at time of death<ref name=":0" />. | ||
== | == Parkinson Plus Syndrome == | ||
Parkinson-plus syndromes are a loose group of neurodegenerative disorders that are characterised by features of Parkinson disease but with other neurological symptoms/signs. They have a poor response to levodopa. Conditions included in Parkinson-plus syndrome include: | |||
* [[Progressive Supranuclear Palsy|Progressive supranuclear palsy]] (PSP) | |||
* [[Multiple System Atrophy|Multiple system atrophy]] (MSA) | |||
* [[Lewy Body Disease]] | |||
* Cortical-basal ganglionic degeneration (CBGD) | |||
* [[Frontotemporal Dementia]] | |||
== Sub Heading 3 == | == Sub Heading 3 == | ||
Revision as of 04:34, 16 March 2022
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton, Aminat Abolade and Mason Trauger
Introduction[edit | edit source]
Parkinsonism is a constellation of signs and symptoms that are characteristically observed in Parkinson’s disease (PD), but that are not necessarily due to PD[1]. Parkinsonism is the primary type of hypokinetic movement disorder, manifesting as rigidity, tremors, and bradykinesia.
Parkinsonism can be categorized into four different types. These are:
• Primary parkinsonism (idiopathic Parkinson's disease)
• Parkinsons Plus Syndrome
• Secondary parkinsonism
• Familial neurodegenerative conditions causing parkinsonism[2]
Early in the disease process, it is often hard to know whether a person has idiopathic Parkinson’s disease or a syndrome that mimics it. These syndromes tend to progress more rapidly than Parkinson’s, present with additional symptoms such as early falling, dementia or hallucinations, and do not respond or respond only for a short time to levodopa therapy[3].[4][5]
Following are descriptions of some of the most common Parkinsonism disorders. Remember many people will not exhibit the cardinal symptoms necessary for a diagnosis of a specific disorder and will simply be labeled “parkinsonism”. For these people a definite diagnosis will only come if the family requests a brain autopsy at time of death[3].
Parkinson Plus Syndrome[edit | edit source]
Parkinson-plus syndromes are a loose group of neurodegenerative disorders that are characterised by features of Parkinson disease but with other neurological symptoms/signs. They have a poor response to levodopa. Conditions included in Parkinson-plus syndrome include:
- Progressive supranuclear palsy (PSP)
- Multiple system atrophy (MSA)
- Lewy Body Disease
- Cortical-basal ganglionic degeneration (CBGD)
- Frontotemporal Dementia
Sub Heading 3[edit | edit source]
Resources[edit | edit source]
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References[edit | edit source]
- ↑ Singer HS, Mink J, Gilbert DL, Jankovic J. Movement disorders in childhood. Academic Press; 2015 Oct 27. Available:https://www.sciencedirect.com/science/article/pii/B9780124115736000152 (accessed 17.3.2022)
- ↑ PD program Different types of Parkinsonism Available:https://pdprogram.org/different-types-parkinsonism/ (accessed 16.3.2022)
- ↑ 3.0 3.1 Parkinson org PD vs parkinsonism Available: https://www.parkinson.org/sites/default/files/attachments/Parkinsons-Disease-vs-Parkinsonisms.pdf (accessed 17.3.2022)
- ↑ Shrimanker I, Tadi P, Sánchez-Manso JC Sept 2021. Parkinsonism.Available: https://www.ncbi.nlm.nih.gov/books/NBK542224/(accessed 17.3.2022)
- ↑ Williams DR, Litvan I. Parkinsonian syndromes. Continuum: lifelong learning in neurology. 2013 Oct;19(5 Movement Disorders):1189.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234134/ (accessed 17.3.2022)
