Felty Syndrome: Difference between revisions
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== Prevalence == | == Prevalence == | ||
The prevalence of FS is an estimate 10 cases per 100,000 people. It is seen in about 1-3% cases of RA, making it a rare rheumatological disorder. <ref name="3" /><ref name="4">Felty Syndrome- NORD (National Organization for Rare Disorders) [Internet]. NORD (National Organization for Rare Disorders). 2016 [cited 2 April 2016]. Available from: http://rarediseases.org/rare-diseases/felty-syndrome/</ref> | |||
FS is three times more common in females than males. However, early occurrence is more common in males. It more commonly affects the Caucasian population, and the mean age of those presenting with FS is between 50-70 years old.<ref name="3" /><ref name="4" /> | |||
== Characteristics/Clinical Presentation == | == Characteristics/Clinical Presentation == | ||
Revision as of 17:28, 5 April 2016
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Top Contributors - Abby Janszen, Shannon Stenger, Rucha Gadgil, Uchechukwu Chukwuemeka, WikiSysop, Kim Jackson, Claire Knott, Lucinda hampton, 127.0.0.1, Elaine Lonnemann and Khloud Shreif
Definition/Description[edit | edit source]
Felty syndrome (FS) is a rare rheumatic disorder that is typically distinguished by the following subsequent conditions: rheumatoid arthritis (RA), low white blood cell count (neutropenia), and an enlarged spleen (splenomegaly), and recurring infections. Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive titleCite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive titleFurthermore, it can be characterized by the triad of rheumatoid arthritis, severe extra-articular disease, and an unexplained neutropenia.
FS, a rare complication of RA, was first described by Dr. Augustus Felty in 1924. It is characterized by a triad of symptoms: seropositive RA with severe joint involvement, neutropenia, and splenomegaly. However, the triad is not required for diagnosis. Splenomegaly and severe joint involvement are not always present in some people with FS, and some people can even present with no symptoms. Neutropenia is the hallmark symptom of FS and is key for diagnosis. FS can be a potentially life-threatening, serious systemic condition due to its increased risk for infection during an immunosuppressed state of RA. Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
Prevalence[edit | edit source]
The prevalence of FS is an estimate 10 cases per 100,000 people. It is seen in about 1-3% cases of RA, making it a rare rheumatological disorder. Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive titleCite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
FS is three times more common in females than males. However, early occurrence is more common in males. It more commonly affects the Caucasian population, and the mean age of those presenting with FS is between 50-70 years old.Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive titleCite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports/ Case Studies[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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