Lung Cancer: Difference between revisions

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== Epidemiology  ==
== Epidemiology  ==


Background epidemiology to the disease or condition (to include prevalence and incidence as appropriate from a UK or Scottish perspective. (You may want to also look at the disease prevalence across different social economic groups).
Lung cancer is one of the most common and serious types of cancer. It is the second highest cancer incidence in both males and females, following prostate cancer in men and breast cancer in women. It is diagnosed in over 41,000 people every year in the UK and is the leading cause of cancer death around the world. In 2008, lung cancer contributed to 13% or 1.6 million of total cancer cases and 18% or 1.4 million cancer-related deaths worldwide. Lung cancer incidence and mortality rates are highest in the United States and developed countries and almost 9 in 10 lung cancer cases occur in people aged 60 years or older. <br><br>


== Aetiology==
== Aetiology==

Revision as of 18:08, 7 June 2015

Welcome to Glasgow Caledonian University Cardiorespiratory Therapeutics Project This project is created by and for the students in the School of Physiotherapy at Glasgow Caledonian University. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Definition/Description[edit | edit source]

Lung cancer is the uncontrolled growth of abnormal cells that start off in one or both lungs and arises from the cells of the respiratory epithelium. Cancer that is formed initially in the lungs is known as primary lung cancer and cancer that begins in another area of the body but then spreads to the lungs is called secondary lung cancer. Primary lung cancer is divided into two types which are classified as small cell lung cancer and non-small cell lung cancer. The classification of these two types of primary lung cancer is established by the type of cells in which the cancer starts.

Non-small-cell lung cancer is the most common type of primary lung cancer, as it accounts for more than 80% of cases. It is further divided into 3 subtypes: squamous cell carcinoma, adenocarcinoma and large-cell carcinoma

Squamous cell carcinoma

  • Located 2/3 central and 1/3 periphery of the lung
  • Arises from large airway epithelial cells
  • Strong association with cigarette smoking
  • Tends to create obstruction and cause distal atelectasis
  • Best prognosis


Adenocarcinoma

  • Located in the periphery of the lung
  • Arises from small airway epithelial cells and type II alveolar cells
  • Most common type of lung cancer in non-smokers and more prevalent in women


Large-cell carcinoma

  • Located in the periphery of the lung
  • Similar to adenocarcinoma but the lesions tend to be larger


Small-cell lung cancer is a highly malignant tumor derived from cells exhibiting neuroendocrine characteristics. It is a less common type that accounts for about 15-20% of cases and usually spreads faster than non-small-cell lung cancer. It is often at a more advanced stage when it is diagnosed (British Lung Foundation, 2015). This type of lung cancer, which has the strongest association with cigarette smoking, leads to the worst prognosis due to it’s rapid growth.

Epidemiology[edit | edit source]

Lung cancer is one of the most common and serious types of cancer. It is the second highest cancer incidence in both males and females, following prostate cancer in men and breast cancer in women. It is diagnosed in over 41,000 people every year in the UK and is the leading cause of cancer death around the world. In 2008, lung cancer contributed to 13% or 1.6 million of total cancer cases and 18% or 1.4 million cancer-related deaths worldwide. Lung cancer incidence and mortality rates are highest in the United States and developed countries and almost 9 in 10 lung cancer cases occur in people aged 60 years or older.

Aetiology[edit | edit source]

The causes of the disease or condition, current thinking and research activity as appropriate

Investigations[edit | edit source]

This may well include any investigations used to gain a diagnosis or that you might need to gain information about your patient assessment.

Clinical Manifestations[edit | edit source]

Clinical manifestations (the signs and symptoms your patient may well present to you on an examination) ensure you relate this back to the underlying pathophysiology.

Physiotherapy and Other Management[edit | edit source]

Physiotherapy and other management. Other health professionals will be treating your patient. What is their input?

Prevention[edit | edit source]

Brief consideration of how this pathology could be prevented and the physiotherapy role in health promotion in relation to prevention of disease or disease progression.

Resources
[edit | edit source]

add appropriate resources here

Recent Related Research (from Pubmed)[edit | edit source]

see tutorial on Adding PubMed Feed

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References[edit | edit source]

see adding references tutorial.