Pelvic Congestion Syndrome: Difference between revisions

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<div class="noeditbox">Welcome to [[Pathophysiology of Complex Patient Problems|PT 635 Pathophysiology of Complex Patient Problems]] This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!</div><div class="editorbox">
<div class="noeditbox">Welcome to [[Pathophysiology of Complex Patient Problems|PT 635 Pathophysiology of Complex Patient Problems]] This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!</div><div class="editorbox">
'''Original Editors '''- [[Pathophysiology of Complex Patient Problems|Students from Bellarmine University's&nbsp;Pathophysiology of Complex Patient Problems project.]]  
'''Original Editors '''- [[Pathophysiology of Complex Patient Problems|Students from Bellarmine University's&nbsp;Pathophysiology of Complex Patient Problems project.]]  
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== Definition/Description  ==
== Definition/Description  ==


Pelvic Congestion Syndrome (PCS) is a chronic pelvic pain condition in which impaired ovarian veins results in the blood to flow backwards instead of forward, or up, towards the heart (1). An insufficient or incompetent valve of a vein within the pelvic region is also associated with PCS due to pain occuring from venous distension and congestion (1).The following term and phrase has also been associated with this condition: ovarian variocele and "varicose veins of the ovaries" (1).<br>
Pelvic Congestion Syndrome (PCS) is a chronic pelvic pain condition in which impaired ovarian veins results in the blood to flow backwards instead of forward, or up, towards the heart (1). An insufficient or incompetent valve of a vein within the pelvic region is also associated with PCS due to pain occuring from venous distension and congestion (1).The following term and phrase has also been associated with this condition: ovarian variocele and "varicose veins of the ovaries" (1).<br>  


== Prevalence  ==
== Prevalence  ==
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Pelvic Congestion Syndrome is often missed due to the supine positioning, typically used for testing, which may cause a decrease in venous distention (2). Presence of PCS may be found through laproscopy, hysteroscopy, or other imaging (i.e. computerized tomography, magnetic resonance imaging, ultrasound) (4).  
Pelvic Congestion Syndrome is often missed due to the supine positioning, typically used for testing, which may cause a decrease in venous distention (2). Presence of PCS may be found through laproscopy, hysteroscopy, or other imaging (i.e. computerized tomography, magnetic resonance imaging, ultrasound) (4).  


<br>Ignacio et al. (2) found two primary imaging modalities utilized to provide further information of venous blood flow and detecting presence varicose veins in the pelvic region, which include:
<br>Ignacio et al. (2) found two primary imaging modalities utilized to provide further information of venous blood flow and detecting presence varicose veins in the pelvic region, which include:  


*Pelvic Ultrasonography which provides a more dynamic image of the blood flow, and
*Pelvic Ultrasonography which provides a more dynamic image of the blood flow, and  
*Computed tomography used for detecting varicose veins in the lower abdominal region, and is more sensitive than ultrasound
*Computed tomography used for detecting varicose veins in the lower abdominal region, and is more sensitive than ultrasound


<br>


 
Ignacio et al also came up with criteria for sonographic diagnosis (2):  
Ignacio et al also came up with criteria for sonographic diagnosis (2):


#Ovarian veins &gt;4mm in diameter  
#Ovarian veins &gt;4mm in diameter  
#Dilation of and tortuous Arcuate veins that communicate with bilateral pelvic veins, and
#Dilation of and tortuous Arcuate veins that communicate with bilateral pelvic veins, and  
#Retrograde, and decreased blood flow of &lt; 3cm/s (particularly of the left ovarian vein)<br>
#Retrograde, and decreased blood flow of &lt; 3cm/s (particularly of the left ovarian vein)<br>


== Etiology/Causes<br>  ==
== Etiology/Causes<br>  ==


Women birthing two or more children (multiparous) can become more susceptible to developing PCS(2). With each pregnancy, a woman's intravascular volume can significantly increase up to sixty percent (2). As intravascular volume increases, so can venous distension(2). If an ovarian vein is subject to excessive distension, valvular incompencies can occur and result in PCS (2). It has also been suggested that estrogen can play a role in the weakening of venous walls, so careful consideration should be taken when hormones are being medically managed (2).
Women birthing two or more children (multiparous) can become more susceptible to developing PCS(2). With each pregnancy, a woman's intravascular volume can significantly increase up to sixty percent (2). As intravascular volume increases, so can venous distension(2). If an ovarian vein is subject to excessive distension, valvular incompencies can occur and result in PCS (2). It has also been suggested that estrogen can play a role in the weakening of venous walls, so careful consideration should be taken when hormones are being medically managed (2).  


<br>Another cause of PCS can be anatomic anomalies that become obstructing in nature. A retroaortic renal vein can result in an obstruction of an ovarian vein, and thus pelvic varices (2). Compression from the superior mesenteric artery can occur on the renal or ovarian vein. This particular compression has been described in the literature as "Nutcracker Syndrome" (2). Additional compression from the common iliac artery can occur on the common iliac vein between the spine and the pelvic brim. The resulting compression cascade can produce pelvic varices or even iliofemoral deep venous thrombosis (2).
<br>Another cause of PCS can be anatomic anomalies that become obstructing in nature. A retroaortic renal vein can result in an obstruction of an ovarian vein, and thus pelvic varices (2). Compression from the superior mesenteric artery can occur on the renal or ovarian vein. This particular compression has been described in the literature as "Nutcracker Syndrome" (2). Additional compression from the common iliac artery can occur on the common iliac vein between the spine and the pelvic brim. The resulting compression cascade can produce pelvic varices or even iliofemoral deep venous thrombosis (2).  


<br>Additionally, surgical complications can lead to the incidence of PCS. The most known surgical association is with a nephrectomy. During this procedure, the ovarian vein is an an increased risk of being cut (1).
<br>Additionally, surgical complications can lead to the incidence of PCS. The most known surgical association is with a nephrectomy. During this procedure, the ovarian vein is an an increased risk of being cut (1).  


== Systemic Involvement  ==
== Systemic Involvement  ==


To date, PCS is not known to lead to any systemic involvement.&nbsp;
To date, PCS is not known to lead to any systemic involvement.&nbsp;  


== Medical Management (current best evidence)  ==
== Medical Management (current best evidence)  ==

Revision as of 01:59, 5 April 2016

 

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Definition/Description[edit | edit source]

Pelvic Congestion Syndrome (PCS) is a chronic pelvic pain condition in which impaired ovarian veins results in the blood to flow backwards instead of forward, or up, towards the heart (1). An insufficient or incompetent valve of a vein within the pelvic region is also associated with PCS due to pain occuring from venous distension and congestion (1).The following term and phrase has also been associated with this condition: ovarian variocele and "varicose veins of the ovaries" (1).

Prevalence[edit | edit source]

Most often seen in women who are of childbearing age, or older (1). Majority of women who are affected have had a history of multiple pregnancies (1). This syndrome can also occur in men and is diagnosed through presentation of visible varicosities on the scrotum (1). Is the cause of about 10-15% of referrals to gynecologists or other pain related clinics (4).

Characteristics/Clinical Presentation 

Pelvic Congestion Syndrome may be asymptomatic and often times may go undiagnosed (4). Can cause continuous or intermittent lower abdominal or pelvic pain, ranging from a dull ache to a sharp severe pain (1). Duration of pain can last more than 6 months (2). The lower abdominal, or pelvic, pain associated with PCS can be felt unilaterally,on one side, or bilaterally, occurring on both left and right sides of the body (1). The pain usually is worse by the end of the day, with long periods of standing, or related to the onset of mensus (1,2).

Other common clinical presentations, noted in Goodman (1), associated with PCS include:

  • Tenderness upon deep palapation of the ovarian point  
  • Dyspareunia  
  • Presence of varicose veins in the buttock and/or lower extremities
  • Headache  
  • Gastrointestinal pain/discomfort  
  • Changes in bowel and bladder  
  • Fatigue  
  • Insomnia  
  • Heaviness feeling felt in the lower abdomen or pelvic region  
  • Lower back pain worsened upon standing upright


Ignacio et al. (2) also found other associated signs and symptoms related to PCS including:

  • Increased pain at the end of the day
  • Pain increased upon sitting and/or standing
  • Lethargy
  • Depression
  • Vaginal discharge
  • Dysmenorrhea
  • Swollen vulva
  • Lumbosacral neuropathy
  • Rectal discomfort

Associated Co-morbidities[edit | edit source]

Impaired circulatory function, such as peripheral vascular disease, is often associated with PCS (1).

Medications[edit | edit source]

Patients with PCS can often be prescribed hormonal medications (4). This pharmacological management of this condition is directed towards decreasing congestion from the varicose veins, and also decreasing blood flow to the varicose veins (5).

Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

Pelvic Congestion Syndrome is often missed due to the supine positioning, typically used for testing, which may cause a decrease in venous distention (2). Presence of PCS may be found through laproscopy, hysteroscopy, or other imaging (i.e. computerized tomography, magnetic resonance imaging, ultrasound) (4).


Ignacio et al. (2) found two primary imaging modalities utilized to provide further information of venous blood flow and detecting presence varicose veins in the pelvic region, which include:

  • Pelvic Ultrasonography which provides a more dynamic image of the blood flow, and
  • Computed tomography used for detecting varicose veins in the lower abdominal region, and is more sensitive than ultrasound


Ignacio et al also came up with criteria for sonographic diagnosis (2):

  1. Ovarian veins >4mm in diameter
  2. Dilation of and tortuous Arcuate veins that communicate with bilateral pelvic veins, and
  3. Retrograde, and decreased blood flow of < 3cm/s (particularly of the left ovarian vein)

Etiology/Causes
[edit | edit source]

Women birthing two or more children (multiparous) can become more susceptible to developing PCS(2). With each pregnancy, a woman's intravascular volume can significantly increase up to sixty percent (2). As intravascular volume increases, so can venous distension(2). If an ovarian vein is subject to excessive distension, valvular incompencies can occur and result in PCS (2). It has also been suggested that estrogen can play a role in the weakening of venous walls, so careful consideration should be taken when hormones are being medically managed (2).


Another cause of PCS can be anatomic anomalies that become obstructing in nature. A retroaortic renal vein can result in an obstruction of an ovarian vein, and thus pelvic varices (2). Compression from the superior mesenteric artery can occur on the renal or ovarian vein. This particular compression has been described in the literature as "Nutcracker Syndrome" (2). Additional compression from the common iliac artery can occur on the common iliac vein between the spine and the pelvic brim. The resulting compression cascade can produce pelvic varices or even iliofemoral deep venous thrombosis (2).


Additionally, surgical complications can lead to the incidence of PCS. The most known surgical association is with a nephrectomy. During this procedure, the ovarian vein is an an increased risk of being cut (1).

Systemic Involvement[edit | edit source]

To date, PCS is not known to lead to any systemic involvement. 

Medical Management (current best evidence)[edit | edit source]

add text here

Physical Therapy Management (current best evidence)[edit | edit source]

add text here

Differential Diagnosis[edit | edit source]

Due to clinical presentation, PCS has an extensive list of differential diagnosis to be ruled out prior to the diagnosis. Ignacio et al. has suggested the following differential diagnosis list:

  • Bowel Pathology
  • Cancer
  • Endometriosis
  • Fibroids
  • Fibromyalgia
  • Ovarian Cyst
  • Pelvic Inflammatory Disorder
  • Porphyria
  • Uterine Prolapse
  • Orthopedic, Neurologic, or Urogenic Pathology (2)


In addition to some characteristics above, Semmel also suggested the remaining differential diagnosis:

  • Leiomyoma
  • Adenomyosis
  • Nutcracker Syndrome
  • Inflammatory Bowel Syndrome
  • Diverticulitis/Diverticulosis/Meckel's Diverticulum
  • Interstitial Cystitis
  • Fascitis
  • Psychosexual Dysfunction
  • Depression (6).

Case Reports/ Case Studies[edit | edit source]

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Resources
[edit | edit source]

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Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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