Neurogenic Inflammation: Difference between revisions
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Neurogenic inflammation (NI) is a physiological process in which mediators are released directly from the cutaneous nerves to initiate an inflammatory reaction in response to tissue damage or a painful stimuli. This results in the production of local inflammatory responses including erythema, swelling, temperature increase, tenderness, and pain. | Neurogenic inflammation (NI) is a physiological process in which mediators are released directly from the cutaneous nerves to initiate an inflammatory reaction in response to tissue damage or a painful stimuli. This results in the production of local inflammatory responses including erythema, swelling, temperature increase, tenderness, and pain. | ||
Neurogenic inflammation has also been implicated in the pathophysiology of numerous diseases, including complex regional pain syndrome, migraine, and irritable bowel and bladder syndromes. However,in the setting of wound healing, neurogenic inflammation helps maintain tissue integrity and facilitate tissue repair.<ref>Chiu IM, von Hehn CA, Woolf CJ. Neurogenic inflammation – the peripheral nervous system’s role in host defense and immunopathology. ''Nat Neurosci''. 2012;15:1063-1067.</ref> | Neurogenic inflammation has also been implicated in the pathophysiology of numerous diseases, including complex regional pain syndrome, migraine, and irritable bowel, arthritis, bladder inflammation, asthma and bladder syndromes. However, in the setting of wound healing, neurogenic inflammation helps maintain tissue integrity and facilitate tissue repair.<ref>Chiu IM, von Hehn CA, Woolf CJ. Neurogenic inflammation – the peripheral nervous system’s role in host defense and immunopathology. ''Nat Neurosci''. 2012;15:1063-1067.</ref> | ||
=== Mechanism of Injury / Pathological Process === | |||
== Management / Interventions == | |||
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== Resources == | |||
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== References == | == References == | ||
Revision as of 17:45, 10 August 2023
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Introduction[edit | edit source]
Neurogenic inflammation (NI) is a physiological process in which mediators are released directly from the cutaneous nerves to initiate an inflammatory reaction in response to tissue damage or a painful stimuli. This results in the production of local inflammatory responses including erythema, swelling, temperature increase, tenderness, and pain.
Neurogenic inflammation has also been implicated in the pathophysiology of numerous diseases, including complex regional pain syndrome, migraine, and irritable bowel, arthritis, bladder inflammation, asthma and bladder syndromes. However, in the setting of wound healing, neurogenic inflammation helps maintain tissue integrity and facilitate tissue repair.[1]
Mechanism of Injury / Pathological Process[edit | edit source]
Management / Interventions[edit | edit source]
add text here relating to management approaches to the condition
Resources[edit | edit source]
add appropriate resources here
References[edit | edit source]
References will automatically be added here, see adding references tutorial.
- ↑ Chiu IM, von Hehn CA, Woolf CJ. Neurogenic inflammation – the peripheral nervous system’s role in host defense and immunopathology. Nat Neurosci. 2012;15:1063-1067.
