Fibroblast: Difference between revisions
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* Tenoblast: specialised fibroblast | * Tenoblast: specialised fibroblast | ||
* Osteoblast: specialised fibroblast | * Osteoblast: specialised fibroblast | ||
* Myofibroblasts: fibroblasts | * Myofibroblasts: contractile fibroblasts, having contractile properties, play a critical part in wound healing. | ||
== Resources == | == Resources == | ||
Revision as of 01:51, 26 June 2022
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton, Vidya Acharya and Kim Jackson
Introduction[edit | edit source]
Fibroblasts are the most common cell in connective tissue and connective tissues permanent residents. They secrete the fibers (notably collagen and elastic) and ground substance of the extracellular matrix.
Fibroblasts are often spindle-shaped with an elongated nucleus. When active fibroblasts are easily recognized by their abundant rough endoplasmic reticulum and prominent Golgi apparatus.[1]
Connective Tissue Repair[edit | edit source]
Connective tissue repair is carried out by new fibroblasts which are derived from cells called pericytes. Pericytes are embedded in the basement membrane of blood capillaries These new fibroblasts then migrate into wounds, following injury, and helping repair the damage.[2]
Contractile fibroblasts, called myofibroblasts are also often generated, and these help to contract wounds.
Terminology[edit | edit source]
- Fibroblast: Synthetically active state
- Fybrocyte: Synthetically inactive state
- Tenoblast: specialised fibroblast
- Osteoblast: specialised fibroblast
- Myofibroblasts: contractile fibroblasts, having contractile properties, play a critical part in wound healing.
Resources[edit | edit source]
- bulleted list
- x
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- numbered list
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References[edit | edit source]
- ↑ Histology Guide Fibroblast Available: https://histologyguide.com//EM-view/EM-006-fibroblast/03-photo-1.html (accessed 26.6.2022)
- ↑ Histology Leeds Fibroblasts Available: https://www.histology.leeds.ac.uk/tissue_types/connective/connective_tissue_fibros.php (accessed 26.6.2022)
