Felty Syndrome: Difference between revisions
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== Definition/Description == | == Definition/Description == | ||
Felty syndrome (FS) is a rare rheumatic disorder that is typically distinguished by the following subsequent conditions: rheumatoid arthritis (RA), low white blood cell count (neutropenia), and an enlarged spleen (splenomegaly), and recurring infections. <ref> | Felty syndrome (FS) is a rare rheumatic disorder that is typically distinguished by the following subsequent conditions: rheumatoid arthritis (RA), low white blood cell count (neutropenia), and an enlarged spleen (splenomegaly), and recurring infections. <ref>RUO-ZHI X, MU-JUN X, ZI-JIE L, RUI-FANG F, DONG-JUN L. Diagnosis of Felty’s syndrome, distinguished from hematological neoplasm: A case report. Oncology Letters [serial on the Internet]. (2014 March), [cited April 2, 2016]; 7(3): 713-716. Available from: Academic Search Complete.</ref><ref>Updated by: Gordon A. Starkebaum a. Felty syndrome: MedlinePlus Medical Encyclopedia [Internet]. Nlm.nih.gov/medlineplus/ency/article/000445.htm</ref>Furthermore, it can be characterized by the triad of rheumatoid arthritis, severe extra-articular disease, and an unexplained neutropenia. | ||
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FS, a rare complication of RA, was first described by Dr. Augustus Felty in 1924. It is characterized by a triad of symptoms: seropositive RA with severe joint involvement, neutropenia, and splenomegaly. However, the triad is not required for diagnosis. Splenomegaly and severe joint involvement are not always present in some people with FS, and some people can even present with no symptoms. Neutropenia is the hallmark symptom of FS and is key for diagnosis. FS can be a potentially life-threatening, serious systemic condition due to its increased risk for infection during an immunosuppressed state of RA.<ref> | FS, a rare complication of RA, was first described by Dr. Augustus Felty in 1924. It is characterized by a triad of symptoms: seropositive RA with severe joint involvement, neutropenia, and splenomegaly. However, the triad is not required for diagnosis. Splenomegaly and severe joint involvement are not always present in some people with FS, and some people can even present with no symptoms. Neutropenia is the hallmark symptom of FS and is key for diagnosis. FS can be a potentially life-threatening, serious systemic condition due to its increased risk for infection during an immunosuppressed state of RA. <ref>Bagher Owlia M, Newmann K, Akhtari M. Felty’s Syndrome, Insights and Updates. TORJ. 2014; 8(1): 129-136.</ref> | ||
== Prevalence == | == Prevalence == | ||
Revision as of 17:17, 5 April 2016
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Top Contributors - Abby Janszen, Shannon Stenger, Rucha Gadgil, Uchechukwu Chukwuemeka, Kim Jackson, WikiSysop, Claire Knott, Lucinda hampton, 127.0.0.1 and Elaine Lonnemann
Definition/Description[edit | edit source]
Felty syndrome (FS) is a rare rheumatic disorder that is typically distinguished by the following subsequent conditions: rheumatoid arthritis (RA), low white blood cell count (neutropenia), and an enlarged spleen (splenomegaly), and recurring infections. [1][2]Furthermore, it can be characterized by the triad of rheumatoid arthritis, severe extra-articular disease, and an unexplained neutropenia.
FS, a rare complication of RA, was first described by Dr. Augustus Felty in 1924. It is characterized by a triad of symptoms: seropositive RA with severe joint involvement, neutropenia, and splenomegaly. However, the triad is not required for diagnosis. Splenomegaly and severe joint involvement are not always present in some people with FS, and some people can even present with no symptoms. Neutropenia is the hallmark symptom of FS and is key for diagnosis. FS can be a potentially life-threatening, serious systemic condition due to its increased risk for infection during an immunosuppressed state of RA. [3]
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- ↑ RUO-ZHI X, MU-JUN X, ZI-JIE L, RUI-FANG F, DONG-JUN L. Diagnosis of Felty’s syndrome, distinguished from hematological neoplasm: A case report. Oncology Letters [serial on the Internet]. (2014 March), [cited April 2, 2016]; 7(3): 713-716. Available from: Academic Search Complete.
- ↑ Updated by: Gordon A. Starkebaum a. Felty syndrome: MedlinePlus Medical Encyclopedia [Internet]. Nlm.nih.gov/medlineplus/ency/article/000445.htm
- ↑ Bagher Owlia M, Newmann K, Akhtari M. Felty’s Syndrome, Insights and Updates. TORJ. 2014; 8(1): 129-136.
