DN4 questionnaire: Difference between revisions

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=== Reliability  ===
=== Reliability  ===


it is a reliable component of the diagnostic work up for painful diabetic polyneuropathy<ref name="p1">Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy.fckLRSpallone V1, Morganti R, D'Amato C, Greco C, Cacciotti L, Marfia GA.</ref>&nbsp;  
it is a reliable component of the diagnostic work up for painful diabetic polyneuropathy<ref name="p1"/>&nbsp;  


&nbsp;Inter-rater agreement coefficient:0.80 (0.71–0.89), and test-retest intra-class correlation coefficient: 0.95 (0.92–0.97)]<ref name="p1">AccessResearchValidity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic componentConcepcion Perez*1,</ref>  
&nbsp;Inter-rater agreement coefficient:0.80 (0.71–0.89), and test-retest intra-class correlation coefficient: 0.95 (0.92–0.97)]<ref name="p1"/>  


The Persian version of DN4 questionnaire is a reliable, valid, feasible, and easily administered tool for precise discrimination neuropathic pain from NNP in Farsi. The characteristics of this test can assist practitioner to diagnose neuropathic pain accurately for both clinical and research purposes.<ref>Validity and reliability of the persian (Farsi) version of the DN4 (Douleur Neuropathique 4 Questions) questionnaire for differential diagnosis of neuropathic from non-neuropathic pains.fckLRMadani SP1, Fateh HR, Forogh B, Fereshtehnejad SM, Ahadi T, Ghaboussi P, Bouhassira D, Raissi GR.</ref>  
The Persian version of DN4 questionnaire is a reliable, valid, feasible, and easily administered tool for precise discrimination neuropathic pain from NNP in Farsi. The characteristics of this test can assist practitioner to diagnose neuropathic pain accurately for both clinical and research purposes.<ref>Validity and reliability of the persian (Farsi) version of the DN4 (Douleur Neuropathique 4 Questions) questionnaire for differential diagnosis of neuropathic from non-neuropathic pains.fckLRMadani SP1, Fateh HR, Forogh B, Fereshtehnejad SM, Ahadi T, Ghaboussi P, Bouhassira D, Raissi GR.</ref>  
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=== Validity  ===
=== Validity  ===


valid fora cut-off value ≥ 4 points<ref name="p1">eliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic componentConcepcion Perez*1,</ref>  
valid fora cut-off value ≥ 4 points<ref name="p1"/>  


DN4 is valid for painful diabetic polyneuropathy, which supports its usefulness as a screening tool for neuropathic pain in diabetes.<ref name="p1">Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy.fckLRSpallone V1, Morganti R, D'Amato C, Greco C, Cacciotti L, Marfia GA.</ref>  
DN4 is valid for painful diabetic polyneuropathy, which supports its usefulness as a screening tool for neuropathic pain in diabetes.<ref name="p1">Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy.fckLRSpallone V1, Morganti R, D'Amato C, Greco C, Cacciotti L, Marfia GA.</ref>  
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=== Sensitivity  ===
=== Sensitivity  ===


The DN4 questionnaire has very good sensitivity (83%) <ref name="p1">http://hqlo.biomedcentral.com/articles/10.1186/1477-7525-5-66</ref>  
The DN4 questionnaire has very good sensitivity (83%) <ref name="p1"/>  


=== Specificity  ===
=== Specificity  ===


it has specificity of &nbsp;(90%) <ref name="p1">http://hqlo.biomedcentral.com/articles/10.1186/1477-7525-5-66</ref>  
it has specificity of &nbsp;(90%) <ref name="p1"/>  


== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed])  ==
== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed])  ==

Revision as of 15:30, 6 June 2017


Summary[edit | edit source]

It is a clinician-administered questionnaire consisting of 10 items. Seven items related to pain quality (i.e. sensory and pain descriptors) are based on an interview with the patient, and 3 items based on the clinical examination [1].The DN4 (which stands for Douleur Neuropathique 4) is one of the questionnaires that can be usefu in diagnosing neuropathic pain. It has components of how the pain feels to the patient but also requires the examining health professional to assess whether there is reduced sensation (hypoaesthesia) to touch or pinprick, and whether light brushing increases or causes pain (allodynia)[2].Questionnaire initially written in French but immediately translated into English by the same team. The scale has been widely used since 2005 because of its simplicity. It evaluates neuropathic pain following central and peripheral neurological lesions.It is also used for diagnostic purposes, allowing the clinician to determine if the pain is of neuropathic origin.[3]
This questionnaire has been well validated in a number of studies.

The DN4 questionnaire was originally developed and validated in French.[4]

Questionnaire[edit | edit source]

http://www.cheo.on.ca/uploads/1199%20DN4NeuropathicDiagnosticQuestionnaireFinal.pdf

Evidance[edit | edit source]

Reliability[edit | edit source]

it is a reliable component of the diagnostic work up for painful diabetic polyneuropathy[5] 

 Inter-rater agreement coefficient:0.80 (0.71–0.89), and test-retest intra-class correlation coefficient: 0.95 (0.92–0.97)][5]

The Persian version of DN4 questionnaire is a reliable, valid, feasible, and easily administered tool for precise discrimination neuropathic pain from NNP in Farsi. The characteristics of this test can assist practitioner to diagnose neuropathic pain accurately for both clinical and research purposes.[6]

The DN4 is an easy-to-use screening tool that is reliable for discriminating between neuropathic and nociceptive pain conditions in daily practice. [7]

Validity[edit | edit source]

valid fora cut-off value ≥ 4 points[5]

DN4 is valid for painful diabetic polyneuropathy, which supports its usefulness as a screening tool for neuropathic pain in diabetes.[5]

Sensitivity[edit | edit source]

The DN4 questionnaire has very good sensitivity (83%) [5]

Specificity[edit | edit source]

it has specificity of  (90%) [5]

Recent Related Research (from Pubmed)[edit | edit source]

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Reference[edit | edit source]

  1. http://hqlo.biomedcentral.com/articles/10.1186/1477-7525-5-66
  2. http://www.gloshospitals.nhs.uk/en/Wards-and-Departments/Departments/Pain-Management/Different-Pains/Nerve-Pain/Assessment-of-Nerve-Pain/DN4-Draft/
  3. http://scale-library.com/assessment_scale_result.php?echelle=DN4%20Questionnaire&retour=liste&scalage=adulte
  4. http://hqlo.biomedcentral.com/articles/10.1186/1477-7525-5-66
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy.fckLRSpallone V1, Morganti R, D'Amato C, Greco C, Cacciotti L, Marfia GA.
  6. Validity and reliability of the persian (Farsi) version of the DN4 (Douleur Neuropathique 4 Questions) questionnaire for differential diagnosis of neuropathic from non-neuropathic pains.fckLRMadani SP1, Fateh HR, Forogh B, Fereshtehnejad SM, Ahadi T, Ghaboussi P, Bouhassira D, Raissi GR.
  7. Validation of the Dutch version of the DN4 diagnostic questionnaire for neuropathic pain.fckLRvan Seventer R1, Vos C, Giezeman M, Meerding WJ, Arnould B, Regnault A, van Eerd M, Martin C, Huygen F.