Creatine Phosphokinase (CK or CPK): Difference between revisions
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== Introduction == | == Introduction == | ||
Creatine phosphokinase (CPK) AKA creatine kinase (CK), is the enzyme that catalyzes the reaction of [[Creatine and Exercise|creatine]] and [[Adenosine triphosphate (ATP)|adenosine triphosphate]] (ATP) to phosphocreatine (PCr) and adenosine diphosphate (ADP). It is a reversible [[Enzymes|enzyme]] reaction that subsequently produces ATP from PCr and ADP. The PCr made is then used to supply tissues and cells that need substantial amounts of ATP, for instance the brain, skeletal muscles, and the heart, with this much needed ATP. Creatine phosphokinase (CK) is a major controller of homeostasis in cells. Numerous conditions cause disruption of CPK levels, including rhabdomyolysis, heart disease, kidney disease, and certain medications.<ref>Aujla RS, Patel R. https://www.ncbi.nlm.nih.gov/books/NBK546624/ StatPearls. Treasure Island (FL).Available:https://www.ncbi.nlm.nih.gov/books/NBK546624/ (accessed 4.2.2024)</ref> | Creatine phosphokinase (CPK) AKA creatine kinase (CK), is the enzyme that catalyzes the reaction of [[Creatine and Exercise|creatine]] and [[Adenosine triphosphate (ATP)|adenosine triphosphate]] (ATP) to phosphocreatine (PCr) and adenosine diphosphate (ADP). It is a reversible [[Enzymes|enzyme]] reaction that subsequently produces ATP from PCr and ADP. The PCr made is then used to supply tissues and cells that need substantial amounts of ATP, for instance the brain, skeletal muscles, and the heart, with this much needed ATP. Creatine phosphokinase (CK) is a major controller of homeostasis in cells. Numerous conditions cause disruption of CPK levels, including rhabdomyolysis, heart disease, kidney disease, and certain medications.<ref>Aujla RS, Patel R. https://www.ncbi.nlm.nih.gov/books/NBK546624/ StatPearls. Treasure Island (FL).Available:https://www.ncbi.nlm.nih.gov/books/NBK546624/ (accessed 4.2.2024)</ref> | ||
[[File:Creatine kinase-phosphocreatine (CK-PCr) energy shuttle..png|center|thumb|500x500px|CKP Energy Shuttle]] | |||
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Revision as of 02:33, 5 February 2024
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Introduction[edit | edit source]
Creatine phosphokinase (CPK) AKA creatine kinase (CK), is the enzyme that catalyzes the reaction of creatine and adenosine triphosphate (ATP) to phosphocreatine (PCr) and adenosine diphosphate (ADP). It is a reversible enzyme reaction that subsequently produces ATP from PCr and ADP. The PCr made is then used to supply tissues and cells that need substantial amounts of ATP, for instance the brain, skeletal muscles, and the heart, with this much needed ATP. Creatine phosphokinase (CK) is a major controller of homeostasis in cells. Numerous conditions cause disruption of CPK levels, including rhabdomyolysis, heart disease, kidney disease, and certain medications.[1]
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References[edit | edit source]
- ↑ Aujla RS, Patel R. https://www.ncbi.nlm.nih.gov/books/NBK546624/ StatPearls. Treasure Island (FL).Available:https://www.ncbi.nlm.nih.gov/books/NBK546624/ (accessed 4.2.2024)
