Compression Bandaging: Difference between revisions

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*    Material:Typically made of stretchable fabric such as cotton, polyester, or a blend.
*    Material:Typically made of stretchable fabric such as cotton, polyester, or a blend.
*    Application:Applied with varying degrees of tension, these bandages conform to the body's shape and provide adjustable compression.
*    Application:Applied with varying degrees of tension, these bandages conform to the body's shape and provide adjustable compression.
* Use Cases: Suitable for sprains, strains, edema management, and securing dressings.<ref>The American Academy of Orthopaedic Surgeons (AAOS). "Understanding Elastic Bandages." Available at: <nowiki>https://orthoinfo.aaos.org/en/treatment/understanding-elastic-bandages/</nowiki></ref><ref>Simpson, A.N., et al. "Elastic Bandage Compression in Treatment of Lower Extremity Venous Ulcers." *Journal of the American Academy of Dermatology.* Available at: <nowiki>https://www.jaad.org/article/S0190-9622(14)01874-2/fulltext</nowiki>
* Use Cases: Suitable for sprains, strains, edema management, and securing dressings.<ref>Choucair M, Phillips TJ. Compression therapy. Dermatol Surg. 1998;24:141–8.</ref>
</ref>


2. '''Crepe Bandages:'''
2. '''Crepe Bandages:'''
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*   Material:Made from cotton or a cotton-polyester blend.
*   Material:Made from cotton or a cotton-polyester blend.
* Application: Applied with moderate tension, crepe bandages are effective for securing dressings and providing light to moderate compression.
* Application: Applied with moderate tension, crepe bandages are effective for securing dressings and providing light to moderate compression.
* Use Cases:Often used for joint support, strains, and minor injuries.<ref>Medical News Today. "Crepe Bandages: Uses, Benefits, and Application." Available at: <nowiki>https://www.medicalnewstoday.com/articles/326415</nowiki>
* Use Cases:Often used for joint support, strains, and minor injuries.<ref>Morison MJ. London: Wolfe; 1992. A Colour Guide to the Nursing Management of Wounds</ref>


   </ref><ref>- Singh, H., et al. "The Efficacy of Crepe Bandage Compression in the Prevention of Injuries." *Journal of Athletic Training.* Available at: <nowiki>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925853/</nowiki>
'''5. Multi-layer Compression Bandages:'''
</ref>
 
3. '''Tubular Bandages:'''
 
*  Description: Tubular bandages are seamless, cylindrical tubes that slide over limbs to provide even compression.
* Material: Usually made of elastic or non-elastic fabric.
* Application:Slipped over the limb like a sock, tubular bandages offer consistent compression and are easy to apply.
* Use Cases:Ideal for edema management, limb support, and securing dressings on irregularly shaped areas.<ref>Wound Care Advisor. "Tubular Bandages: A Review of Uses and Application Techniques." Available at: <nowiki>https://woundcareadvisor.com/tubular-bandages-a-review-of-uses-and-application-techniques/</nowiki>
 
   </ref><ref>Eriksson, A., et al. "Comparison of Compression Therapy Using Multilayer Bandages and Tubular Bandages." *International Wound Journal.* Available at: <nowiki>https://pubmed.ncbi.nlm.nih.gov/27666539/</nowiki>
</ref>
 
'''4. Foam Bandages:'''
 
*   Description:Foam bandages consist of soft, cushioned material with or without an adhesive backing.
*   Material: Foam bandages are typically made of polyurethane or silicone.
*  Application:These bandages provide gentle compression along with padding, making them suitable for fragile or sensitive skin.
*   Use Cases: Recommended for wound care, pressure ulcer prevention, and protecting bony prominences.<ref>Wound Source. "Choosing the Right Foam Dressing." Available at: <nowiki>https://www.woundsource.com/blog/choosing-right-foam-dressing</nowiki>
</ref><ref>Santamaria, N.M., et al. "Effectiveness of Foam Dressings for Pressure Ulcers: A Systematic Review." *International Wound Journal.* Available at: <nowiki>https://pubmed.ncbi.nlm.nih.gov/22093421/</nowiki>
</ref>


'''5. Multi-layer Compression Bandages:'''
Multilayered bandaging involves the application of several layers of compression bandages to effectively manage venous leg ulcers. These layers typically include padding, a crepe bandage, and cohesive or adhesive bandages.


* Description:Multi-layer compression bandages consist of several layers of different materials, providing graduated compression.
* Padding:The first layer consists of a soft padding material, such as orthopedic wool or foam, which provides cushioning and protection to the wound site.
*   Material: Combinations of elastic, foam, and cohesive materials are often used.
* Crepe Bandage:Over the padding, a crepe bandage is applied to provide initial compression and support. Crepe bandages are elastic and conform well to the shape of the leg, helping to maintain consistent pressure.
*  Application:Applied in a specific order, these bandages exert high pressure at the base and gradually decrease towards the top, promoting venous return.
* Cohesive or Adhesive Bandages:Finally, cohesive or adhesive bandages are applied over the crepe bandage to provide additional compression and secure the layers in place. These bandages adhere to themselves without the need for pins or clips, ensuring that the compression remains uniform.
*  Use Cases: Essential for managing venous leg ulcers, lymphedema, and chronic venous insufficiency.<ref>Wounds UK. "Multi-layer Compression Bandages: Principles and Application." Available at: <nowiki>https://www.wounds-uk.com/journals/original-article/multi-layer-compression-bandages-principles-and-application</nowiki>


 </ref><ref>O'Meara, G., et al. "A Systematic Review of the Effectiveness of Multi-layer Compression Dressings in the Treatment of Venous Leg Ulcers." *Journal of Clinical Nursing.* Available at: <nowiki>https://pubmed.ncbi.nlm.nih.gov/21129135/</nowiki>
The multilayered bandaging technique aims to promote venous return, reduce edema, and facilitate wound healing by applying graduated compression to the affected limb. This method has been found to be effective in managing venous leg ulcers and preventing recurrence.<ref>Nair, B. (2014). Compression therapy for venous leg ulcers. Indian Dermatology Online Journal, 5(3), 378–382. doi: 10.4103/2229-5178.137822.</ref>
</ref>


== Understanding Compressive Bandages: Short Stretch vs. Long Stretch ==
== Understanding Compressive Bandages: Short Stretch vs. Long Stretch ==
Compressive bandages are essential in various medical scenarios, with short stretch and long stretch bandages being the primary types. Each type offers distinct advantages and considerations, influencing their application and efficacy.
'''Long-Stretch Bandages:'''
 
* '''Short Stretch Bandages-'''Short stretch bandages exhibit minimal extensibility, providing consistent pressure upon application. This characteristic makes them suitable for conditions requiring sustained compression, such as venous insufficiency and lymphedema. <ref>Maynard A, et al. "Comparative study of short-stretch versus long-stretch bandages in the management of venous ulcers." *Journal of Wound Care*. 2020;29(Suppl 1):S12-S17.
 
   


</ref>
* Elasticity:Long-stretch bandages are composed of elastic materials with high elongation capacity (exceeding 100%).
* '''Long Stretch Bandages-'''Long stretch bandages possess high elasticity, allowing for greater stretch during application. They are commonly used in acute injury management, offering flexibility and support while minimizing constriction. However, frequent readjustment may be necessary to maintain optimal compression levels. <ref>Patel R, et al. "Efficacy of long-stretch bandages in acute sports-related injuries: a randomized controlled trial." *Journal of Orthopaedic Research*. 2019;37(4):512-518.
* Resting Pressure:They offer less tolerable resting pressure compared to short-stretch bandages.
* Continuous Pressure: Long-stretch bandages provide continuous pressure during movement and exercise.
* Smooth Application:Due to their elastane filament composition, long-stretch bandages offer smooth application and conformability, making them suitable for daily wear.
* Ideal for Mobile Patients: They excel in sustaining pressure during movement, making them ideal for patients who are active.
* Usge:Long-stretch bandages are commonly used for conditions where continuous pressure during movement is required, but they may be less effective in managing edema compared to short-stretch bandages.


</ref>
'''Short-Stretch Bandages:'''


=== '''Clinical Considerations''' ===
* Material: Short-stretch bandages are composed of non-elastic or rigid materials with an elongation capacity ranging from 10% to 100%.
When choosing between short stretch and long stretch bandages, clinicians must consider factors such as the patient's condition, mobility requirements, and desired level of compression. ''Short stretch bandages'' provide stable compression for chronic conditions, while ''long stretch bandages'' offer comfort and adaptability for acute injuries.
* Pressure:They exert higher working pressures compared to long-stretch bandages.
* Resting Pressure: Short-stretch bandages have low resting pressure and high working pressure.
* Tissue Hydrostatic Pressure:These bandages effectively limit the available space for fluid accumulation and promote tissue hydrostatic pressure.
* Fluid Drainage: Short-stretch bandages facilitate fluid drainage, reinforce tissue hydrostatic pressure, and improve venous and lymphatic flow.
* Usage: Short-stretch bandages are preferred for conditions where high working pressure is required, such as managing edema and promoting venous return.


Understanding the characteristics and applications of each type of compressive bandage is crucial for effective patient care and treatment outcomes.
<ref>Aboalasaad, A. R. R., Sirková, B. K., Bílá, P., & Khalil, A. A. S. (Year of publication). Comparative study of long- and short-stretch woven compression bandages. Technologies and Structures Department, Technical University of Liberec, Liberec 46117, Czech Republic. Department of Textile Evaluation, Technical University of Liberec, Liberec 46117, Czech Republic. *Corresponding author: Aboalasaad, A. R. R. Email: [email protected].</ref><ref>Santandrea, S., Benassi, M., & Tedeschi, R. (2023). Comparison of short-stretch bandage and long-stretch bandage for post-traumatic hand edema. International Journal of Surgery Case Reports, 111, 108854. <nowiki>https://doi.org/10.1016/j.ijscr.2023.108854</nowiki></ref>


== Techniques ==
== Techniques ==
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* Skin care practices including moisturization, hygiene, and protection against trauma.
* Skin care practices including moisturization, hygiene, and protection against trauma.
* Recognition of warning signs such as increased pain, numbness, tingling, skin changes, or temperature abnormalities, warranting prompt medical attention.
* Recognition of warning signs such as increased pain, numbness, tingling, skin changes, or temperature abnormalities, warranting prompt medical attention.
* Instructions on bandage care, including hygiene, avoidance of excessive moisture, and proper reapplication techniques .<ref name=":3" />
* Instructions on bandage care, including hygiene, avoidance of excessive moisture, and proper reapplication techniques .


== Advanced Techniques and Modalities ==
== Advanced Techniques and Modalities ==
Line 140: Line 121:
* Custom-made compression garments tailored to individual patient needs and anatomical considerations, offering a precise fit and enhanced comfort.
* Custom-made compression garments tailored to individual patient needs and anatomical considerations, offering a precise fit and enhanced comfort.
* Neuromuscular electrical stimulation (NMES) applied concurrently with compression therapy to improve muscle pump function and enhance fluid mobilization <ref name=":1" />
* Neuromuscular electrical stimulation (NMES) applied concurrently with compression therapy to improve muscle pump function and enhance fluid mobilization <ref name=":1" />
== Future Directions ==
Future developments in compression therapy are poised to address several key areas:
* Advanced materials and manufacturing techniques for compression garments, leading to lighter, more breathable, and durable products.
* Integration of wearable technology and smart textiles into compression garments, allowing for continuous monitoring of limb parameters and real-time adjustment of compression levels.
* Development of personalized compression therapy protocols based on patient-specific factors such as limb geometry, tissue characteristics, and activity levels.
* Exploration of adjunctive therapies such as low-level laser therapy (LLLT), pneumatic compression massage, and tissue engineering approaches to augment the efficacy of compression therapy and promote tissue regeneration.
* Adoption of telehealth platforms and remote monitoring solutions to facilitate patient education, adherence monitoring, and timely intervention in compression therapy programs <ref name=":2" />


== Safety Considerations in Compression Bandaging for Lymphedema Treatment ==
== Safety Considerations in Compression Bandaging for Lymphedema Treatment ==
Line 155: Line 127:
This highlights the critical importance of proper training and expertise in compression bandaging techniques. Clinicians should undergo comprehensive education and hands-on training to ensure proficiency in assessing patient needs, selecting appropriate bandaging materials, and applying optimal pressure levels. Moreover, regular monitoring and evaluation during treatment are vital to detect any complications early on and adjust the bandaging regimen accordingly.  
This highlights the critical importance of proper training and expertise in compression bandaging techniques. Clinicians should undergo comprehensive education and hands-on training to ensure proficiency in assessing patient needs, selecting appropriate bandaging materials, and applying optimal pressure levels. Moreover, regular monitoring and evaluation during treatment are vital to detect any complications early on and adjust the bandaging regimen accordingly.  


By prioritizing safety and expertise in compression bandaging, healthcare providers can maximize the therapeutic benefits while minimizing the risks for patients with lymphedema.<ref>Moffatt CJ, Franks PJ, Doherty DC, et al. Lymphoedema: an underestimated health problem. *QJM*. 2003;96(10):731-738. [PubMed PMID: 14500879].
By prioritizing safety and expertise in compression bandaging, healthcare providers can maximize the therapeutic benefits while minimizing the risks for patients with lymphedema<ref>Ko DS, Lerner R, Klose G, et al. Effective treatment of lymphedema of the extremities. *Arch Surg*. 1998;133(4):452-458. [PubMed PMID: 9565122].</ref>.<ref>Moffatt CJ, Franks PJ, Doherty DC, et al. Lymphoedema: an underestimated health problem. *QJM*. 2003;96(10):731-738. [PubMed PMID: 14500879].
 
</ref><ref>Ko DS, Lerner R, Klose G, et al. Effective treatment of lymphedema of the extremities. *Arch Surg*. 1998;133(4):452-458. [PubMed PMID: 9565122].


</ref>
</ref>

Revision as of 20:16, 26 March 2024

Original Editor - Alicia Fernandes Top Contributors - Alicia Fernandes, Kim Jackson and Ewa Jaraczewska

Introduction[edit | edit source]

Compression bandaging is a vital aspect of physiotherapy interventions, particularly in the management of edema and venous insufficiency. This article aims to explore the techniques, uses, indications, and red flags associated with compression bandaging.

Types of Compressive Bandages[edit | edit source]

1. Elastic Bandages:

  •    Description: Elastic bandages are commonly used for providing compression and support to injured or strained areas.
  •    Material:Typically made of stretchable fabric such as cotton, polyester, or a blend.
  •    Application:Applied with varying degrees of tension, these bandages conform to the body's shape and provide adjustable compression.
  • Use Cases: Suitable for sprains, strains, edema management, and securing dressings.[1]

2. Crepe Bandages:

  •   Description: Crepe bandages are woven with a crinkled texture, providing moderate compression and support.
  •   Material:Made from cotton or a cotton-polyester blend.
  • Application: Applied with moderate tension, crepe bandages are effective for securing dressings and providing light to moderate compression.
  • Use Cases:Often used for joint support, strains, and minor injuries.[2]

5. Multi-layer Compression Bandages:

Multilayered bandaging involves the application of several layers of compression bandages to effectively manage venous leg ulcers. These layers typically include padding, a crepe bandage, and cohesive or adhesive bandages.

  • Padding:The first layer consists of a soft padding material, such as orthopedic wool or foam, which provides cushioning and protection to the wound site.
  • Crepe Bandage:Over the padding, a crepe bandage is applied to provide initial compression and support. Crepe bandages are elastic and conform well to the shape of the leg, helping to maintain consistent pressure.
  • Cohesive or Adhesive Bandages:Finally, cohesive or adhesive bandages are applied over the crepe bandage to provide additional compression and secure the layers in place. These bandages adhere to themselves without the need for pins or clips, ensuring that the compression remains uniform.

The multilayered bandaging technique aims to promote venous return, reduce edema, and facilitate wound healing by applying graduated compression to the affected limb. This method has been found to be effective in managing venous leg ulcers and preventing recurrence.[3]

Understanding Compressive Bandages: Short Stretch vs. Long Stretch[edit | edit source]

Long-Stretch Bandages:

  • Elasticity:Long-stretch bandages are composed of elastic materials with high elongation capacity (exceeding 100%).
  • Resting Pressure:They offer less tolerable resting pressure compared to short-stretch bandages.
  • Continuous Pressure: Long-stretch bandages provide continuous pressure during movement and exercise.
  • Smooth Application:Due to their elastane filament composition, long-stretch bandages offer smooth application and conformability, making them suitable for daily wear.
  • Ideal for Mobile Patients: They excel in sustaining pressure during movement, making them ideal for patients who are active.
  • Usge:Long-stretch bandages are commonly used for conditions where continuous pressure during movement is required, but they may be less effective in managing edema compared to short-stretch bandages.

Short-Stretch Bandages:

  • Material: Short-stretch bandages are composed of non-elastic or rigid materials with an elongation capacity ranging from 10% to 100%.
  • Pressure:They exert higher working pressures compared to long-stretch bandages.
  • Resting Pressure: Short-stretch bandages have low resting pressure and high working pressure.
  • Tissue Hydrostatic Pressure:These bandages effectively limit the available space for fluid accumulation and promote tissue hydrostatic pressure.
  • Fluid Drainage: Short-stretch bandages facilitate fluid drainage, reinforce tissue hydrostatic pressure, and improve venous and lymphatic flow.
  • Usage: Short-stretch bandages are preferred for conditions where high working pressure is required, such as managing edema and promoting venous return.

[4][5]

Techniques[edit | edit source]

The application of compression bandages requires a thorough understanding of the underlying condition and the patient's needs. Several techniques exist, including:

1. Spiral Technique: This involves applying the bandage in a spiral pattern, ensuring even pressure distribution along the limb.[6]

2. Figure-of-Eight Technique: Here, the bandage is applied in a crisscross pattern, resembling the figure-of-eight, providing additional support and compression.[7]

3.Modified Robert-Jones Bandage: This technique involves multiple layers of padding followed by a tightly applied bandage, commonly used in the management of acute injuries.[6]

Uses[edit | edit source]

Compression bandaging serves various purposes in physiotherapy practice:

1. Edema Management:It is effective in reducing swelling associated with acute injuries, chronic conditions like lymphedema, or post-surgical swelling.[8]

2. Venous Insufficiency:Compression bandaging aids in improving venous return, reducing symptoms of venous insufficiency such as pain, swelling, and skin changes.[9]

3. Joint Stability: In cases of ligamentous injuries or joint instability, compression bandaging provides external support, enhancing proprioception and stability.[8]

4. Ulcer Healing: For individuals with venous ulcers, compression bandaging promotes wound healing by improving circulation and reducing edema.[7]

Indications[edit | edit source]

Compression bandaging is indicated in various clinical scenarios, including:

1. Chronic Venous Insufficiency:Patients presenting with symptoms like leg swelling, varicose veins, and venous ulcers benefit from compression therapy.[9]

2. Lymphedema:Management of lymphedema involves complex decongestive therapy, including compression bandaging, to reduce limb swelling and improve lymphatic drainage.[6]

3. Acute Injuries:Following acute trauma such as sprains, strains, or fractures, compression bandaging helps control swelling and provides support during the healing process.[8]

4. Post-Surgical Care:After orthopedic surgeries or procedures involving extensive tissue manipulation, compression bandaging aids in reducing post-operative edema and promoting tissue healing.[7]

Red Flags[edit | edit source]

While compression bandaging is generally safe, certain red flags warrant attention:

1. Excessive Pain: Persistent or increasing pain beneath the bandage may indicate compromised circulation or excessive pressure, requiring immediate assessment.[6]

2. Numbness/Tingling: Sensory changes like numbness or tingling suggest nerve compression and necessitate bandage adjustment to alleviate pressure.[8]

3. Skin Changes:Signs of skin irritation, blistering, or discoloration beneath the bandage may indicate skin compromise or allergic reactions.[7]

4. Temperature Changes: Significant temperature changes in the affected limb, such as increased warmth or coolness, can signal vascular compromise or infection.[9]

Contraindications[edit | edit source]

In addition to arterial insufficiency, acute deep vein thrombosis, and severe peripheral neuropathy, contraindications to compression bandaging may include:

  • Compromised skin integrity such as dermatitis, open wounds, or fragile skin.
  • Acute inflammatory conditions where compression may exacerbate swelling and pain.
  • Allergic reactions to bandage materials, adhesive components, or topical agents used under the bandage [8].

Monitoring and Evaluation[edit | edit source]

Monitoring and evaluation of patients undergoing compression therapy involve:

  • Regular assessment of limb circumference, comparing measurements over time to track changes in edema.
  • Evaluation of skin condition beneath the bandage for signs of pressure damage, irritation, or allergic reactions.
  • Subjective assessment of patient-reported symptoms such as pain, discomfort, or changes in sensation.
  • Utilization of objective measures like ankle-brachial pressure index (ABPI) to assess vascular status and ensure adequate perfusion [6]

Patient Education[edit | edit source]

Patient education in compression bandaging should encompass:

  • Proper limb elevation techniques to enhance venous return and reduce edema.
  • Skin care practices including moisturization, hygiene, and protection against trauma.
  • Recognition of warning signs such as increased pain, numbness, tingling, skin changes, or temperature abnormalities, warranting prompt medical attention.
  • Instructions on bandage care, including hygiene, avoidance of excessive moisture, and proper reapplication techniques .

Advanced Techniques and Modalities[edit | edit source]

Advanced techniques and modalities in compression therapy may include:

  • Intermittent pneumatic compression devices (IPC) which intermittently apply and release pressure to the limb, enhancing venous return and lymphatic drainage.
  • Multi-layer compression systems combining different materials and bandage layers to provide graduated compression and optimal pressure distribution.
  • Custom-made compression garments tailored to individual patient needs and anatomical considerations, offering a precise fit and enhanced comfort.
  • Neuromuscular electrical stimulation (NMES) applied concurrently with compression therapy to improve muscle pump function and enhance fluid mobilization [7]

Safety Considerations in Compression Bandaging for Lymphedema Treatment[edit | edit source]

While compression bandaging is considered a cornerstone in the management of lymphedema, it is essential to recognize the potential risks associated with its application by untrained clinicians. Improperly applied compression can lead to adverse effects, including skin damage, circulation impairment, and exacerbation of lymphatic fluid buildup.

This highlights the critical importance of proper training and expertise in compression bandaging techniques. Clinicians should undergo comprehensive education and hands-on training to ensure proficiency in assessing patient needs, selecting appropriate bandaging materials, and applying optimal pressure levels. Moreover, regular monitoring and evaluation during treatment are vital to detect any complications early on and adjust the bandaging regimen accordingly.

By prioritizing safety and expertise in compression bandaging, healthcare providers can maximize the therapeutic benefits while minimizing the risks for patients with lymphedema[10].[11]

Conclusion[edit | edit source]

In summary, compression bandaging is a fundamental aspect of physiotherapy, vital for managing edema and venous insufficiency. Various types and techniques exist, each with specific applications and considerations. While effective, improper application by untrained clinicians can pose risks, emphasizing the importance of safety measures and expertise. Future advancements hold promise for improved outcomes and accessibility. Overall, compression bandaging remains indispensable in enhancing patient care and quality of life.

Reference[edit | edit source]

  1. Choucair M, Phillips TJ. Compression therapy. Dermatol Surg. 1998;24:141–8.
  2. Morison MJ. London: Wolfe; 1992. A Colour Guide to the Nursing Management of Wounds
  3. Nair, B. (2014). Compression therapy for venous leg ulcers. Indian Dermatology Online Journal, 5(3), 378–382. doi: 10.4103/2229-5178.137822.
  4. Aboalasaad, A. R. R., Sirková, B. K., Bílá, P., & Khalil, A. A. S. (Year of publication). Comparative study of long- and short-stretch woven compression bandages. Technologies and Structures Department, Technical University of Liberec, Liberec 46117, Czech Republic. Department of Textile Evaluation, Technical University of Liberec, Liberec 46117, Czech Republic. *Corresponding author: Aboalasaad, A. R. R. Email: [email protected].
  5. Santandrea, S., Benassi, M., & Tedeschi, R. (2023). Comparison of short-stretch bandage and long-stretch bandage for post-traumatic hand edema. International Journal of Surgery Case Reports, 111, 108854. https://doi.org/10.1016/j.ijscr.2023.108854
  6. 6.0 6.1 6.2 6.3 6.4 Mayrovitz, H. N. (2010). The standard of care for lymphedema: current concepts and physiological considerations. *Lymphatic Research and Biology*, 8(1), 9-10.
  7. 7.0 7.1 7.2 7.3 7.4 O'Brien, J., Edwards, H., Stewart, I., & Gibbs, H. (2001). A comparison of 2 types of compression bandage for the treatment of venous leg ulceration. *Archives of Dermatology*, 137(12), 1631-1636.
  8. 8.0 8.1 8.2 8.3 8.4 Partsch, H. (2008). Compression therapy: clinical and experimental evidence. *Annals of Vascular Diseases*, 1(1), 16-20.
  9. 9.0 9.1 9.2 Moffatt, C. J., & Franks, P. J. (2007). Lymphoedema: an underestimated health problem. *QJM: An International Journal of Medicine*, 100(10), 713-728.
  10. Ko DS, Lerner R, Klose G, et al. Effective treatment of lymphedema of the extremities. *Arch Surg*. 1998;133(4):452-458. [PubMed PMID: 9565122].
  11. Moffatt CJ, Franks PJ, Doherty DC, et al. Lymphoedema: an underestimated health problem. *QJM*. 2003;96(10):731-738. [PubMed PMID: 14500879].