Extracellular Matrix

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton and Tolulope Adeniji  

Introduction[edit | edit source]

The extracellular matrix (ECM) is the non-cellular component present within all tissues and organs, providing a essential physical scaffolding for the cellular constituents (components of the ECM linking together to form a structurally stable composite). ECM components not only provide a scaffold for the tissue but also give tensile strength and limit overstretch of the organ. The ECM holds water, ensures suitable hydration of the tissue, and participates in a selective barrier to the external environment. The ECM also initiates crucial biochemical and biomechanical cues for tissue morphogenesis, differentiation and homeostasis[1][2].

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References[edit | edit source]

  1. Simona Pompili, Giovanni Latella, Eugenio Gaudio, Roberta Sferraand Antonella Vetuschi The Charming World of the Extracellular Matrix: A Dynamic and Protective Network of the Intestinal Wall Available: https://www.frontiersin.org/articles/10.3389/fmed.2021.610189/full (accessed 28.6.2022)
  2. Christian Frantz,Kathleen M. Stewart,Valerie M. Weaver The extracellular matrix at a glance Available: https://journals.biologists.com/jcs/article/123/24/4195/31378/The-extracellular-matrix-at-a-glance (accessed 28.7.2022)