Ramsay Hunt Syndrome

Original Editor - Wendy Walker

Lead Editors  - Wendy Walker

Introduction
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Ramsay Hunt syndrome is defined as an acute peripheral facial neuropathy associated with erythematous vesicular rash of the skin of the ear canal, auricle (also termed herpes zoster oticus), and/or mucous membrane of the oropharynx.

Mechanism of Injury / Pathological Process
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PP RHS.png

Clinical Presentation[edit | edit source]

The presenting feature is often pain deep within the ear. 

A herpetic rash or blisters, which may be on the skin of the ear canal, auricle or both.

Diagnostic Procedures[edit | edit source]

In most cases, the diagnosis is made purely on clinical findings: the presence of herpetic blisters in and around the ear, accompanied in most cases by pain in and around the ear and an ipsilateral facial palsy.

On occasions virological studies, both serological and molecular, can be used to confirm the clinical diagnosis.

In particular, VZV antigen detection by direct immunofluorescence assay (DFA) is used, which has sensitivity of 90% and specificity close to 99%[1].

Structural lesions (such as Acoustic Neuroma) can be ruled out by MRI or CT scan.

Outcome Measures[edit | edit source]

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Management / Interventions
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Differential Diagnosis
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Key Evidence[edit | edit source]

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Resources
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Case Studies[edit | edit source]

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Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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  1. Coffin SE, Hodinka RL. Utility of direct immunofluorescence and virus culture for detection of varicella-zoster virus in skin lesions. J Clin Microbiol. 1995 Oct. 33(10):2792-5