Lab Value Interpretation: Difference between revisions

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==Introduction==
==Introduction==


[[File:Lab values.jpg|frameless|right]]Physical therapists should not rely exclusively on a single laboratory finding; they should also consider a variety or other clinical factors. Likewise, it is important to understand the significance of trends in the values over time<ref name=":0">1.   James T., Traci N., Kim L. Academy of Acute Care Physical Therapy-APTA Task Force on Lab Values.  Laboratory values interpretation Resource. 2017</ref>. Laboratory value tests are one factor in determining the overall health of our patients. For many tests, the normal ranges will vary depending on age, gender, race, or other factors<ref name=":1">Physicaltherapy.com. Available from: http://www.physicaltherapy.com/articles/essential-role-lab-values-and-3637 </ref>.
[[File:Lab values.jpg|frameless|right]]Using laboratory values can be a key piece of assessment to determine what is occurring within the body of a patient. There are numerous laboratory tests that can be done. The most common tests include chemistry panels, hematology (such as the complete blood count), and blood gases.


=== Risk and benefit considerations to therapeutic intervention ===
=== Risk and benefit considerations to therapeutic intervention ===
The fundamental consideration when reviewing patient laboratory findings is toward determining an appropriate plan of care and weighing the anticipated benefit of a therapy intervention against the potential of the patient. Physical therapists should carefully anticipate the physiological changes that might have occurred whenever a laboratory value is out of range. They should also be aware of the heightened risk level if a value should fall into the critical range. It is critical to understand pertinent lab values and the subsequent potential of adverse events when practicing in this kind of practice setting. To begin or continue interventions on patients that we’re seeing in the acute care setting, we always need to use clinical decision making<ref name=":0" />.  The Lab values alone may or may not determine whether you’re going to intervene with a patient, or whether you’re going to hold<ref name=":1" />.
The fundamental consideration when reviewing patient laboratory findings is toward determining an appropriate plan of care and weighing the anticipated benefit of a therapy intervention against the potential of the patient.  


Physical therapists should:
* Carefully anticipate the physiological changes that might have occurred whenever a laboratory value is out of range.
* Be aware of the heightened risk level if a value should fall into the critical range.
* Be aware of the importance of understanding pertinent lab values and the subsequent potential of adverse events when practicing in this kind of practice setting.
When commencing or continuing care of patients in the acute care setting, always use sound clinical decision making<ref name=":0">1.   James T., Traci N., Kim L. Academy of Acute Care Physical Therapy-APTA Task Force on Lab Values.  Laboratory values interpretation Resource. 2017</ref>.  The Lab values alone may or may not determine whether you’re going to intervene with a patient, or whether you’re going to hold<ref name=":1">Physicaltherapy.com. Available from: http://www.physicaltherapy.com/articles/essential-role-lab-values-and-3637 </ref>.
== Be aware ==
Things to consider when looking at the patient’s condition
Things to consider when looking at the patient’s condition
* Potential drug interactions
* Potential drug interactions
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* Electrolyte panels might change with intravenous infusions, medications, and diet
* Electrolyte panels might change with intravenous infusions, medications, and diet
* Chronic medical conditions (such as anemia) might be asymptomatic during exercise, while a patient with precipitous drop in hemoglobin and hematocrit might require urgent medical attention.
* Chronic medical conditions (such as anemia) might be asymptomatic during exercise, while a patient with precipitous drop in hemoglobin and hematocrit might require urgent medical attention.
COMPLETE BLOOD COUNT<ref>Flashcard Machine: available from: http://www.flashcardmachine.com/contraindications-to-ptinacutecaresetting.html </ref>
 
== Complete Blood Count ==
Complete blood count is one of the most basic laboratory examinations to assess the overall health status of a patient. It can help diagnose infections, autoimmune disorders, anemia, and other blood diseases.<ref>Nurse Buff [https://www.nursebuff.com/laboratory-values-for-nurses/ Laboratory Values and Interpretation – A Nurse’s Ultimate Guide] Available :https://www.nursebuff.com/laboratory-values-for-nurses/ (accessed 29.5.2021)</ref><ref>Flashcard Machine: available from: http://www.flashcardmachine.com/contraindications-to-ptinacutecaresetting.html </ref>


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Resistive exercise (>5,000 mm<sup>3</sup> as tolerated)
Resistive exercise (>5,000 mm<sup>3</sup> as tolerated)
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|}
ELECTROLYTES<ref name=":2">1.      Physical Therapy Reviewer. Available from: http://ptreviewer.com/lab-values-3/  </ref>
 
== Electrolytes ==
[[Electrolytes]] are minerals that are involved in some of the important functions in our body. Serum electrolytes are routinely ordered for a patient admitted to a hospital as a screening test for electrolyte and acid-base imbalances.<ref>Nurse labs Lab Values Available from:https://nurseslabs.com/normal-lab-values-nclex-nursing/#serum_electrolytes-2 (accessed 29.5.2021)</ref>
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!Lab values
!Lab values
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|95-105mEq/L      
|95-105mEq/L      
|Reduction: often occur during metabolic alkalosis
|Reduction: often occur during metabolic alkalosis
Elevations: Metabolic acidosis
Elevations: Metabolic acidosis<ref name=":2">1.      Physical Therapy Reviewer. Available from: http://ptreviewer.com/lab-values-3/  </ref>
|}
|}
COAGULATION<ref name=":2" />
 
== Coagulation ==
Clotting is what prevents excessive bleeding, the blood moving through your vessels shouldn’t clot. If such clots form, they can travel through the bloodstream to the heart, lungs, or brain. This can cause a heart attack, stroke, or even death.
 
Coagulation tests measure the blood’s ability to clot, and how long it takes to clot. Testing can help assess the risk of excessive bleeding or developing clots (thrombosis) somewhere in your blood vessels. Coagulation tests are useful in monitoring people who take medications that affect clotting ability. Coagulation tests are also sometimes recommended before surgery.
 
Conditions that can cause coagulation problems include:
 
* Liver disease
* Thrombophilia, which is excessive clotting
* Hemophilia, which is an inability to clot normally
 
There are many types of coagulation tests. Some of the more common are listed below.<ref>Health line [https://www.healthline.com/health/coagulation-tests#purpose Coagulation tests] Available from: https://www.healthline.com/health/coagulation-tests#purpose (accessed 29.5.2021)</ref>
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|Lab values
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>6.0 PT contraindication
>6.0 PT contraindication
|}
|}
The outline was created to assist the clinician with lab value considerations for the general population. The clinician should be aware that “norm” are created for the healthy adult, and each patient’s lab value should be interpreted within the context of the patient’s current medical status<ref name=":0" />. Pediatrics population lab values range is not included above.
The above outline was created to assist the clinician with lab value considerations for the general population.  
 
* Be aware that “norm” are created for the healthy adult, and each patient’s lab value should be interpreted within the context of the patient’s current medical status<ref name=":0" />.  
* Pediatrics population lab values range is not included above<ref name=":2" />.


The video below gives a good introduction to lab values and normal ranges
The video below gives a good introduction to lab values and normal ranges

Revision as of 07:41, 29 May 2021

Introduction[edit | edit source]

Lab values.jpg

Using laboratory values can be a key piece of assessment to determine what is occurring within the body of a patient. There are numerous laboratory tests that can be done. The most common tests include chemistry panels, hematology (such as the complete blood count), and blood gases.

Risk and benefit considerations to therapeutic intervention[edit | edit source]

The fundamental consideration when reviewing patient laboratory findings is toward determining an appropriate plan of care and weighing the anticipated benefit of a therapy intervention against the potential of the patient.

Physical therapists should:

  • Carefully anticipate the physiological changes that might have occurred whenever a laboratory value is out of range.
  • Be aware of the heightened risk level if a value should fall into the critical range.
  • Be aware of the importance of understanding pertinent lab values and the subsequent potential of adverse events when practicing in this kind of practice setting.

When commencing or continuing care of patients in the acute care setting, always use sound clinical decision making[1].  The Lab values alone may or may not determine whether you’re going to intervene with a patient, or whether you’re going to hold[2].

Be aware[edit | edit source]

Things to consider when looking at the patient’s condition

  • Potential drug interactions
  • Significant trends in the values over time
  • Electrolyte panels might change with intravenous infusions, medications, and diet
  • Chronic medical conditions (such as anemia) might be asymptomatic during exercise, while a patient with precipitous drop in hemoglobin and hematocrit might require urgent medical attention.

Complete Blood Count[edit | edit source]

Complete blood count is one of the most basic laboratory examinations to assess the overall health status of a patient. It can help diagnose infections, autoimmune disorders, anemia, and other blood diseases.[3][4]

Lab values Normal range Rehabilitation consideration
Hematocrit(%RBC) 43-49%(male)    

38-44%(female)

No exercise (<25%)

light exercise (25-30%)

Resistive exercise (>30%)

Platelets 150,000-350,000/µL No exercise (<20,000µL)

Light exercise (20,000-50,000µL)

Resistive exercise (>50,000µL)

Hemoglobin 14.4-16.6gm/dL (male)

12.2-14.7gm/dl (female)

No exercise (<8gm/dl)

light exercise (8-10gm/dl)

Resistive exercise (>10gm/dl)

White blood cell(WBC)    4,500-11,000 mm3 No exercise (<5,000 mm3 )

Light exercise (>5,000 mm3)

Resistive exercise (>5,000 mm3 as tolerated)

Electrolytes[edit | edit source]

Electrolytes are minerals that are involved in some of the important functions in our body. Serum electrolytes are routinely ordered for a patient admitted to a hospital as a screening test for electrolyte and acid-base imbalances.[5]

Lab values Normal range Rehabilitation consideration
Sodium  135-145mEq/L Reduction: Cramps, weakness, confusion

Elevation: Fluid retention, Swelling, Hypertension

Potassium  3.5-5.0mEq/L Reductions: Flattened T waves, arrthymias

Elevations: Peaked T waves, shortened QT interval

Calcium  8.5-10.5mg/dl     Reductions (Moderate to severe): parathesias, muscle spasms and seizure and

QT interval prolongation.

Elevations (severe only): Bradycardia, AV block, and short QT interval, coma

Magnesium         1.7 to 2.2mg/dl  Reductions: prolonged PR or QT intervals, T-Waves flattening or inversion, SVT.

Elevation: weakness, respiratory failure, coma, paralysis.

Chloride  95-105mEq/L       Reduction: often occur during metabolic alkalosis

Elevations: Metabolic acidosis[6]

Coagulation[edit | edit source]

Clotting is what prevents excessive bleeding, the blood moving through your vessels shouldn’t clot. If such clots form, they can travel through the bloodstream to the heart, lungs, or brain. This can cause a heart attack, stroke, or even death.

Coagulation tests measure the blood’s ability to clot, and how long it takes to clot. Testing can help assess the risk of excessive bleeding or developing clots (thrombosis) somewhere in your blood vessels. Coagulation tests are useful in monitoring people who take medications that affect clotting ability. Coagulation tests are also sometimes recommended before surgery.

Conditions that can cause coagulation problems include:

  • Liver disease
  • Thrombophilia, which is excessive clotting
  • Hemophilia, which is an inability to clot normally

There are many types of coagulation tests. Some of the more common are listed below.[7]

Lab values Normal range Rehabilitation consideration
Prothrombin time(PTT) 11-12.5sec Assesses extrinsic pathway (fast system)

Therapeutic range: 1-2 times normal

Risk of bleeding: >2-3 times normal

International normalized

Ratio (INR)

0.9-1.1   normalized ratio PT, used to assess effect of warfarin

therapeutic range: Afib/DVT/PE (2-3)

Valve replacement (2.5-3.5)

Risk of bleeding: >4.0 light exercise only

>5.0 hold exercise, PT eval only

>6.0 PT contraindication

The above outline was created to assist the clinician with lab value considerations for the general population.

  • Be aware that “norm” are created for the healthy adult, and each patient’s lab value should be interpreted within the context of the patient’s current medical status[1].
  • Pediatrics population lab values range is not included above[6].

The video below gives a good introduction to lab values and normal ranges

[8]

References[edit | edit source]

  1. 1.0 1.1 1.   James T., Traci N., Kim L. Academy of Acute Care Physical Therapy-APTA Task Force on Lab Values. Laboratory values interpretation Resource. 2017
  2. Physicaltherapy.com. Available from: http://www.physicaltherapy.com/articles/essential-role-lab-values-and-3637
  3. Nurse Buff Laboratory Values and Interpretation – A Nurse’s Ultimate Guide Available :https://www.nursebuff.com/laboratory-values-for-nurses/ (accessed 29.5.2021)
  4. Flashcard Machine: available from: http://www.flashcardmachine.com/contraindications-to-ptinacutecaresetting.html
  5. Nurse labs Lab Values Available from:https://nurseslabs.com/normal-lab-values-nclex-nursing/#serum_electrolytes-2 (accessed 29.5.2021)
  6. 6.0 6.1 1.      Physical Therapy Reviewer. Available from: http://ptreviewer.com/lab-values-3/  
  7. Health line Coagulation tests Available from: https://www.healthline.com/health/coagulation-tests#purpose (accessed 29.5.2021)
  8. Khanacacemymedicine. Introduction to lab values and normal ranges | Health & Medicine | Khan Academy. Available from: https://www.youtube.com/watch?v=_mGszRbve9s (last accessed 26.4.2019)