Multiple Organ Dysfunction Syndrome: Difference between revisions
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'''Original Editor '''- [[User: | '''Original Editor '''- [[User:Lucinda hampton|Lucinda hampton]] | ||
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== Introduction == | == Introduction == | ||
Multiple organ dysfunction syndrome (MODS) is one of the most common syndromes of critical illness and the leading cause of mortality among critically ill patients. | |||
Multiple organ dysfunction syndrome is the clinical consequence of a dysregulated inflammatory response, triggered by clinically diverse factors with the main pillar of management being invasive organ support. | |||
During the last years, the advances in the clarification of the molecular pathways that trigger, mitigate, and determine the outcome of MODS have led to the increasing recognition of MODS as a distinct disease entity with distinct etiology, pathophysiology, and potential future therapeutic interventions. | |||
Given the lack of effective treatment for MODS, its early recognition, the early intensive care unit admission, and the initiation of invasive organ support remain the most effective strategies of preventing its progression and improving outcomes<ref>Gourd NM, Nikitas N. [https://journals.sagepub.com/doi/10.1177/0885066619871452 Multiple organ dysfunction syndrome.] Journal of intensive care medicine. 2020 Dec;35(12):1564-75.Available from: https://journals.sagepub.com/doi/10.1177/0885066619871452 (accessed 28.2.2021)</ref>. | |||
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Revision as of 07:20, 28 February 2021
Original Editor - Lucinda hampton
Top Contributors - Lucinda hampton, Uchechukwu Chukwuemeka and Carina Therese Magtibay
Introduction[edit | edit source]
Multiple organ dysfunction syndrome (MODS) is one of the most common syndromes of critical illness and the leading cause of mortality among critically ill patients.
Multiple organ dysfunction syndrome is the clinical consequence of a dysregulated inflammatory response, triggered by clinically diverse factors with the main pillar of management being invasive organ support.
During the last years, the advances in the clarification of the molecular pathways that trigger, mitigate, and determine the outcome of MODS have led to the increasing recognition of MODS as a distinct disease entity with distinct etiology, pathophysiology, and potential future therapeutic interventions.
Given the lack of effective treatment for MODS, its early recognition, the early intensive care unit admission, and the initiation of invasive organ support remain the most effective strategies of preventing its progression and improving outcomes[1].
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Resources[edit | edit source]
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References[edit | edit source]
- ↑ Gourd NM, Nikitas N. Multiple organ dysfunction syndrome. Journal of intensive care medicine. 2020 Dec;35(12):1564-75.Available from: https://journals.sagepub.com/doi/10.1177/0885066619871452 (accessed 28.2.2021)
