Medication and Falls: Difference between revisions
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== What is a Fall? == | == What is a Fall? == | ||
== What is Polypharmacy? == | == What is Polypharmacy? == | ||
== Medications Associated with Increased Risk of Falls == | == Medications Associated with Increased Risk of Falls == | ||
{| border="1" cellspacing="1" summary="Adapted from The FallSafe Project" cellpadding="1" width="900" align="left" | |||
|+ Psychotropic Drugs and Falls Risk<ref name="FallSafe">Darowski A. Dwight J. Reynolds J. Medicines and Falls in Hospital: Guidance Sheet [ONLINE] available from https://www.rcplondon.ac.uk/sites/default/files/documents/medicines-and-falls2.pdf date accessed 14/01/2015</ref> | |||
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| '''Medication Group''' | |||
| '''Overall Risk Category''' | |||
| '''Commonly Used Medications''' | |||
| '''Effects on Risk''' | |||
|- | |||
| Sedatives | |||
| | |||
<u>'''''HIGH RISK'''''</u> | |||
Can cause falls alone | |||
| | |||
Lorazepam, Temazepam, Nitrazepam | |||
similar '''''-epam'''''suffix | |||
| Drowsiness, slows reactions, impaired balance. | |||
|- | |||
| Sedating Antidepressants | |||
| | |||
'''<u>''HIGH RISK''</u>''' | |||
Can cause falls alone | |||
| Amitriptyline, Nortriptyline | |||
| Orthostatic hypotension, drowsiness, slow reactions. '''DOUBLE THE RATE OF FALLS''' | |||
|- | |||
| Monoamine Oxidase Inhibitors | |||
| | |||
'''<u>''HIGH RISK''</u>''' | |||
Can cause falls alone | |||
| Phenelzine, Moclobemide | |||
| Severe orthostatic hypotension | |||
|- | |||
| For Psychosis Agitation | |||
| | |||
'''<u>''HIGH RISK''</u>''' | |||
Can cause falls alone | |||
| Haloperidol, Chlorpromazine, Olanzapine | |||
| Orthostatic hypotension, slow reflexes, loss of balance | |||
|- | |||
| Selective Serotonin Reuptake Inhibitors (SSRI) and Serotonin and Noradrenaline Reuptake Inhibitor )SNRI) | |||
| | |||
'''<u>''MODERATE RISK''</u>''' | |||
Can cause falls in combination | |||
| Fluoxetine, Sertaline, Paroxetine, Venlafaxine, Duloetine | |||
| Increased risk of falls with fractures, orthostatic hypotension, bradycardia, impaired sleep quality | |||
|- | |||
| Opiate Analegsics | |||
| | |||
''<u>'''HIGH RISK'''</u>''<u></u> | |||
Can cause falls alone<br> | |||
| Codeine, Morphine, Tramadol | |||
| Sedates, slows reactions, impairs balance, delirium | |||
|- | |||
| Anti Epileptics | |||
| '''<u>''HIGH RISK''</u>''' | |||
| Phenytoin, Carbamazepine, Phenobarbitone | |||
| Cerebellar damage, ataxia, slowed reactions | |||
|- | |||
| | |||
| '''<u>''MODERATE RISK''</u>''' | |||
| Sodium Valporate, Gabapentin | |||
| Some association with falls risk | |||
|- | |||
| Parkinson's Disease - Dopamine Agonists | |||
| '''<u>''HIGH RISK''</u>''' | |||
| Roprinerole, Pramipexole | |||
| Delirium, orthostatic hypotension | |||
|- | |||
| Parkinson's Disease - MAOI-B Inhibitors | |||
| '''<u>''HIGH RISK''</u>''' | |||
| Selegiline | |||
| Orthostatic hypotension (Difficult to assess due to high falls risk in PD as the disease process) | |||
|- | |||
| Muscle Relaxant | |||
| '''<u>''MODERATE RISK''</u>''' | |||
| Baclofen | |||
| Reduced muscle tone, sedative | |||
|- | |||
| Vestibular Sedative | |||
| '''<u>''POSSIBLE CAUSES''</u>''' | |||
| Prochlorperazine, Cinnarazine, Betahistine | |||
| Prochlor... - Dopamine agonist which may cause movement disorder in long term, sedating | |||
|- | |||
| Anticholinergics acting on Bladder | |||
| '''<u>''POSSIBLE CAUSES''</u>''' | |||
| Oxybutinin, Solifenacin, Tolterodine, Solifenacin | |||
| Known CNS effects. | |||
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== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) == | == Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) == |
Revision as of 14:16, 14 January 2015
Original Editors - Scott Buxton
Top Contributors -Scott Buxton, Lucinda hampton, Sai Kripa, Kim Jackson, WikiSysop, Evan Thomas and Chelsea Mclene
What is a Fall?[edit | edit source]
What is Polypharmacy?[edit | edit source]
Medications Associated with Increased Risk of Falls[edit | edit source]
Medication Group | Overall Risk Category | Commonly Used Medications | Effects on Risk |
Sedatives |
HIGH RISK Can cause falls alone |
Lorazepam, Temazepam, Nitrazepam similar -epamsuffix |
Drowsiness, slows reactions, impaired balance. |
Sedating Antidepressants |
HIGH RISK Can cause falls alone |
Amitriptyline, Nortriptyline | Orthostatic hypotension, drowsiness, slow reactions. DOUBLE THE RATE OF FALLS |
Monoamine Oxidase Inhibitors |
HIGH RISK Can cause falls alone |
Phenelzine, Moclobemide | Severe orthostatic hypotension |
For Psychosis Agitation |
HIGH RISK Can cause falls alone |
Haloperidol, Chlorpromazine, Olanzapine | Orthostatic hypotension, slow reflexes, loss of balance |
Selective Serotonin Reuptake Inhibitors (SSRI) and Serotonin and Noradrenaline Reuptake Inhibitor )SNRI) |
MODERATE RISK Can cause falls in combination |
Fluoxetine, Sertaline, Paroxetine, Venlafaxine, Duloetine | Increased risk of falls with fractures, orthostatic hypotension, bradycardia, impaired sleep quality |
Opiate Analegsics |
HIGH RISK Can cause falls alone |
Codeine, Morphine, Tramadol | Sedates, slows reactions, impairs balance, delirium |
Anti Epileptics | HIGH RISK | Phenytoin, Carbamazepine, Phenobarbitone | Cerebellar damage, ataxia, slowed reactions |
MODERATE RISK | Sodium Valporate, Gabapentin | Some association with falls risk | |
Parkinson's Disease - Dopamine Agonists | HIGH RISK | Roprinerole, Pramipexole | Delirium, orthostatic hypotension |
Parkinson's Disease - MAOI-B Inhibitors | HIGH RISK | Selegiline | Orthostatic hypotension (Difficult to assess due to high falls risk in PD as the disease process) |
Muscle Relaxant | MODERATE RISK | Baclofen | Reduced muscle tone, sedative |
Vestibular Sedative | POSSIBLE CAUSES | Prochlorperazine, Cinnarazine, Betahistine | Prochlor... - Dopamine agonist which may cause movement disorder in long term, sedating |
Anticholinergics acting on Bladder | POSSIBLE CAUSES | Oxybutinin, Solifenacin, Tolterodine, Solifenacin | Known CNS effects. |
Recent Related Research (from Pubmed)[edit | edit source]
References[edit | edit source]
- ↑ Darowski A. Dwight J. Reynolds J. Medicines and Falls in Hospital: Guidance Sheet [ONLINE] available from https://www.rcplondon.ac.uk/sites/default/files/documents/medicines-and-falls2.pdf date accessed 14/01/2015