Hepatitis A, B, C: Difference between revisions

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== Characteristics/Clinical Presentation  ==
== Characteristics/Clinical Presentation  ==


Hepatitis A symptoms usually do not appear until 2-6 weeks after you have been exposed to the virus. They are usually mild, but can last up to several months (2-6 months), especially in adults. The symptoms include:<br>1. Dark urine<br>2. Fatigue<br>3. Itching<br>4. Loss of appetite<br>5. Low-grade fever<br>6. Nausea and vomiting<br>7. Pale or clay-colored stools<br>8. Jaundice<br>9. Abdominal pain<br>10. Headache<br>11. Diarrhea<br>12. Muscle Pain<ref name="Mayo Clinic Hep A" /><br>It is important to note that not everyone will develop signs and symptoms of the virus.<ref name="PubMed Hep A" /><br>A vaccination is recommended for children age 12-23 months and for adults who are at high risk for the infection.<ref name="International Foundation Hep A" />
Hepatitis A symptoms usually do not appear until 2-6 weeks after you have been exposed to the virus. They are usually mild, but can last up to several months (2-6 months), especially in adults. The symptoms include:<br>1. Dark urine<br>2. Fatigue<br>3. Itching<br>4. Loss of appetite<br>5. Low-grade fever<br>6. Nausea and vomiting<br>7. Pale or clay-colored stools<br>8. Jaundice<br>9. Abdominal pain<br>10. Headache<br>11. Diarrhea<br>12. Muscle Pain<ref name="Mayo Clinic Hep A" /><br>It is important to note that not everyone will develop signs and symptoms of the virus.<ref name="Foundation International Hep A" /><br>A vaccination is recommended for children age 12-23 months and for adults who are at high risk for the infection.<ref name="International Foundation Hep A" />  


Early on, Hepatitis C usually is asymptomatic. When signs and symptoms begin to set in, they are generally mild and flu-like. Associated signs and symptoms of hepatitis C include:<br>1. Fatigue<br>2. Fever<br>3. Nausea or poor appetite<br>4. Muscle and joint pains<br>5. Tenderness of your liver<ref name="Mayo Clinic Hep C" /><br>6. Abdominal pain<br>7. Dark urine<br>8. Grey-coloured feces<br>9. Jaundice<ref name="WHO Hep C" /><br>10. Abdominal swelling<br>11. Itching<ref name="PubMed Hep C">PubMed Health. Hepatitis C. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001329/</ref><br>About 75-85% of recently infected people develop chronic disease and 60-70% of chronically infected people develop chronic liver disease. Also 5-20% develop cirrhosis and 1-5% die from cirrhosis or liver cancer.<ref name="WHO Hep C" />
Early on, Hepatitis C usually is asymptomatic. When signs and symptoms begin to set in, they are generally mild and flu-like. Associated signs and symptoms of hepatitis C include:<br>1. Fatigue<br>2. Fever<br>3. Nausea or poor appetite<br>4. Muscle and joint pains<br>5. Tenderness of your liver<ref name="Mayo Clinic Hep C" /><br>6. Abdominal pain<br>7. Dark urine<br>8. Grey-coloured feces<br>9. Jaundice<ref name="WHO Hep C" /><br>10. Abdominal swelling<br>11. Itching<ref name="PubMed Hep C">PubMed Health. Hepatitis C. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001329/</ref><br>About 75-85% of recently infected people develop chronic disease and 60-70% of chronically infected people develop chronic liver disease. Also 5-20% develop cirrhosis and 1-5% die from cirrhosis or liver cancer.<ref name="WHO Hep C" />  


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Revision as of 06:38, 10 March 2013

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Original Editors - Emily Schmidt & Allyson Simmonds from Bellarmine University's Pathophysiology of Complex Patient Problems project.

Lead Editors - Your name will be added here if you are a lead editor on this page.  Read more.

Definition/Description[edit | edit source]

Hepatitis A is a contagious liver infection cause by the hepatitis A virus. It causes inflammation that affects your livers ability to function.[1] It is the most common of the two hepatitis viruses enterically transmitted hepatitis viruses in the US and one of the two that is vaccine preventable.[2]




Hepatitis C is an infection caused by a virus that attacks the liver and leads to inflammation. Most people who have the infection often do not know that they have the disease, and are often asymptomatic. It is considered to be among the most serious of the hepatitis viruses.[3] About 80% of people who have the virus develop chronic hepatitis, and many people also can develop cirrhosis or even liver cancer.[4]

Prevalence[edit | edit source]

About 3,600 cases of Hepatitis A are reported each year. However, since not all people are symptomatic, several more people are infected than are diagnosed and reported.[5]

Every year around 3-4 million people are infected with the hepatitis C virus. About 150 million people are chronically infected and at risk of developing liver cirrhosis and even liver cancer. More than 350,000 people die from hepatitis C-related liver disease every year.[6]

Characteristics/Clinical Presentation[edit | edit source]

Hepatitis A symptoms usually do not appear until 2-6 weeks after you have been exposed to the virus. They are usually mild, but can last up to several months (2-6 months), especially in adults. The symptoms include:
1. Dark urine
2. Fatigue
3. Itching
4. Loss of appetite
5. Low-grade fever
6. Nausea and vomiting
7. Pale or clay-colored stools
8. Jaundice
9. Abdominal pain
10. Headache
11. Diarrhea
12. Muscle Pain[1]
It is important to note that not everyone will develop signs and symptoms of the virus.[2]
A vaccination is recommended for children age 12-23 months and for adults who are at high risk for the infection.[7]

Early on, Hepatitis C usually is asymptomatic. When signs and symptoms begin to set in, they are generally mild and flu-like. Associated signs and symptoms of hepatitis C include:
1. Fatigue
2. Fever
3. Nausea or poor appetite
4. Muscle and joint pains
5. Tenderness of your liver[3]
6. Abdominal pain
7. Dark urine
8. Grey-coloured feces
9. Jaundice[6]
10. Abdominal swelling
11. Itching[8]
About 75-85% of recently infected people develop chronic disease and 60-70% of chronically infected people develop chronic liver disease. Also 5-20% develop cirrhosis and 1-5% die from cirrhosis or liver cancer.[6]


Associated Co-morbidities[edit | edit source]

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Medications[edit | edit source]

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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Etiology/Causes[edit | edit source]

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Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Alternative/Holistic Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports/ Case Studies[edit | edit source]

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Resources
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Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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  1. 1.0 1.1 Mayo Clinic. Hepatitis A. http://www.mayoclinic.com/health/hepatitis-a/DS00397
  2. 2.0 2.1 Hepatitis Foundation International. Hepatitis A (HAV). http://www.hepatitisfoundation.org/HEPATITIS/Hepatitis-A.html
  3. 3.0 3.1 Mayo Clinic. Hepatitis C. http://www.mayoclinic.com/health/hepatitis-c/DS00097
  4. Hepatitis Foundation International. Hepatitis C (HCV). http://www.hepatitisfoundation.org/HEPATITIS/Hepatitis-C.html
  5. PubMed Health. Hepatitis A. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001323/
  6. 6.0 6.1 6.2 World Health Organization. Hepatitis C. http://www.who.int/mediacentre/factsheets/fs164/en/
  7. Cite error: Invalid <ref> tag; no text was provided for refs named International Foundation Hep A
  8. PubMed Health. Hepatitis C. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001329/