Computerized Adventitious Respiratory Sounds Analysis

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Objective
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There is a need to develop simple, noninvasive, and sensitive outcome measures for respiratory therapy. Adventitious respiratory sounds (ie, crackles and wheezes) can be objectively characterized with computerized respiratory sound analysis (CORSA) and have been shown to contribute for diagnosis purposes; however, their potential for use as outcome measures is unknown.

Respiratory diseases are a major cause of societal, health, and economic burdens worldwide.[1] Therefore, in the last decade, significant research efforts have been dedicated to improve early diagnosis and routine monitoring of patients with respiratory diseases to allow timely interventions. However, addressing these issues has been highly challenging since available respiratory measures such as spirometry are dependent on patient motivation and cooperation, and other tests such as blood gas analysis and imaging are not available in all clinical settings and are expensive. [2][3]

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  1. World Health Organization. The World Health Report 2008: primary health care—now more than ever. World Health Organization, Geneva, Switzerland 2008.
  2. Hayes D Jr, Kraman SS. The physiologic basis of spirometry. Respir Care 2009;54(12):1717-1726.
  3. Marques A, Bruton A, Barney A. Clinically useful outcome measures for physiotherapy airway clearance techniques: a review. Phys Ther Rev 2006;11(4):299-307.