Tendon Biomechanics: Difference between revisions
Evan Thomas (talk | contribs) No edit summary |
Evan Thomas (talk | contribs) No edit summary |
||
| Line 3: | Line 3: | ||
'''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}} | '''Top Contributors''' - {{Special:Contributors/{{FULLPAGENAME}}}} | ||
</div> | </div> | ||
== Tendon Structure, Composition, and Mechanical Properties == | |||
Tendons have a hierarchy of fibrillar arrangement that is sequentially composed of collagen molecules, fibrils, fibers, fascicles (or fiber bundles), and the tendon unit. Tendon units are surrounded by epitenon, which functions to reduce friction with adjacent tissues. | |||
The key to the tendons’ tensile strength is collagen.11 Type I collagen accounts for about 70–80% of the dry weight of normal tendons. In addition to type I collagen, many other types of collagen are also present, including type III (form rapid cross-links in stabilizing repair sites in the case of tears), type V (regulates collagen fibril diameter), and type XII (provides lubrication between collagen fibers). | |||
In addition to collagen, many proteoglycans (e.g. aggrecan and decorin) and glycoproteins (e.g. tenascin-C, fibronectin, and elastin) also have important functions in tendons. Aggrecan holds water and resists compression, and decorin facilitates fibrillar slippage. Tenascin-C, fibronectin, and elastin function to enhance mechanical stability, facilitate tendon healing, and allow tendons to return to their prestretched lengths after physiological loading, respectively. | |||
In addition to collagen, many proteoglycans (e.g. aggrecan and decorin) and glycoproteins (e.g. tenascin-C, fibronectin, and elastin) also have important functions in tendons. Aggrecan holds water and resists compression, and decorin facilitates fibrillar slippage. Tenascin-C, fibronectin, and elastin function to enhance mechanical stability, facilitate tendon healing, and allow tendons to return to their prestretched lengths after physiological loading, respectively. | |||
== Physiological Mechanoresponses == | == Physiological Mechanoresponses == | ||
| Line 46: | Line 45: | ||
|} | |} | ||
<br> | <br> | ||
== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) == | == Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) == | ||
| Line 52: | Line 51: | ||
<rss>http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss_guid=1XYaWIOtNnK8vnX6XWyy0KFdYTMazJo24TQIBw0AmTbuLO1AJj|charset=UTF-8|short|max=10</rss> | <rss>http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss_guid=1XYaWIOtNnK8vnX6XWyy0KFdYTMazJo24TQIBw0AmTbuLO1AJj|charset=UTF-8|short|max=10</rss> | ||
</div> | </div> | ||
== References == | |||
== References == | |||
<references /> | <references /> | ||
Revision as of 19:33, 26 December 2015
Original Editors - Evan Thomas
Top Contributors - Evan Thomas, Lucinda hampton, Simisola Ajeyalemi, Kim Jackson, Wanda van Niekerk, 127.0.0.1, Admin, WikiSysop, Claire Knott and Rucha Gadgil
Tendon Structure, Composition, and Mechanical Properties[edit | edit source]
Tendons have a hierarchy of fibrillar arrangement that is sequentially composed of collagen molecules, fibrils, fibers, fascicles (or fiber bundles), and the tendon unit. Tendon units are surrounded by epitenon, which functions to reduce friction with adjacent tissues.
The key to the tendons’ tensile strength is collagen.11 Type I collagen accounts for about 70–80% of the dry weight of normal tendons. In addition to type I collagen, many other types of collagen are also present, including type III (form rapid cross-links in stabilizing repair sites in the case of tears), type V (regulates collagen fibril diameter), and type XII (provides lubrication between collagen fibers).
In addition to collagen, many proteoglycans (e.g. aggrecan and decorin) and glycoproteins (e.g. tenascin-C, fibronectin, and elastin) also have important functions in tendons. Aggrecan holds water and resists compression, and decorin facilitates fibrillar slippage. Tenascin-C, fibronectin, and elastin function to enhance mechanical stability, facilitate tendon healing, and allow tendons to return to their prestretched lengths after physiological loading, respectively.
Physiological Mechanoresponses[edit | edit source]
Pathological Mechanoresponses[edit | edit source]
The Differential Effects of Mechanical Loading on Tendons[1][edit | edit source]
| Mechanical Load Level | Effects on Tendon |
|---|---|
|
Low |
• ↓ Tensile strength |
|
Moderate |
• ↑ Tensile strength |
|
Excessive |
• ↓ Tensile strength |
Recent Related Research (from Pubmed)[edit | edit source]
Failed to load RSS feed from http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss_guid=1XYaWIOtNnK8vnX6XWyy0KFdYTMazJo24TQIBw0AmTbuLO1AJj|charset=UTF-8|short|max=10: Error parsing XML for RSS
References[edit | edit source]
- ↑ Wang JHC, Guo Q, Li B. Tendon Biomechanics and Mechanobiology - A Minireview of Basic Concepts and Recent Advancements. J Hand Ther, 2012; 25(2): 133–141.
