Tendon Biomechanics: Difference between revisions
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== The Differential Effects of Mechanical Loading on Tendons<ref name="Wang 2012">Wang JHC, Guo Q, Li B. Tendon Biomechanics and Mechanobiology - A Minireview of Basic Concepts and Recent Advancements. J Hand Ther, 2012; 25(2): 133–141.</ref> == | == The Differential Effects of Mechanical Loading on Tendons<ref name="Wang 2012">Wang JHC, Guo Q, Li B. Tendon Biomechanics and Mechanobiology - A Minireview of Basic Concepts and Recent Advancements. J Hand Ther, 2012; 25(2): 133–141.</ref> == | ||
{| cellpadding="2" border="1" style="border: 1px solid darkgray;" | |||
|- | |||
! scope="col" width="200" | Mechanical Load Level | |||
! scope="col" width="400" | Effects on Tendon | |||
|- | |||
| | |||
Low | |||
| | |||
• ↓ Tensile strength <br> • ↓ Size <br> • ↓ Collagen production <br> • ↓ Anabolic activities <br> • ↑ Catabolic activities | |||
|- | |||
| | |||
Moderate | |||
| | |||
• ↑ Tensile strength <br> • ↑ Collagen synthesis <br> • ↓ Collagen degradation <br> • ↓ Adhesions <br> • ↓ Inflammatory mediator (e.g. prostaglandin E2, PGE2) <br> • ↑ Tendon stem cells (TSCs) differentiating into tenocytes | |||
|- | |||
| width="200" | | |||
Excessive | |||
| width="400" | | |||
• ↓ Tensile strength <br> • ↓ Collagen organization <br> • ↑ Myofibroblasts <br> • ↑ Inflammatory mediators <br> • ↑ TSCs differentiating into nontenocytes (adipocytes, osteocytes, chondrocytes) <br> • ↑ Leukotrienes (↑ edema) | |||
|} | |||
<br> | |||
== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) == | == Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) == | ||
Revision as of 09:47, 21 December 2015
Original Editors - Evan Thomas
Top Contributors - Evan Thomas, Lucinda hampton, Simisola Ajeyalemi, Kim Jackson, Wanda van Niekerk, 127.0.0.1, Admin, WikiSysop, Claire Knott and Rucha Gadgil
Tendon Structure, Composition, and Mechanical Properties[edit | edit source]
Physiological Mechanoresponses[edit | edit source]
Pathological Mechanoresponses[edit | edit source]
The Differential Effects of Mechanical Loading on Tendons[1][edit | edit source]
| Mechanical Load Level | Effects on Tendon |
|---|---|
|
Low |
• ↓ Tensile strength |
|
Moderate |
• ↑ Tensile strength |
|
Excessive |
• ↓ Tensile strength |
Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
- ↑ Wang JHC, Guo Q, Li B. Tendon Biomechanics and Mechanobiology - A Minireview of Basic Concepts and Recent Advancements. J Hand Ther, 2012; 25(2): 133–141.
