Trapezius Myalgia: Difference between revisions

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== Search Strategy ==
== Definition/Description ==
 
[[File:Trapezius - Kenhub.png|alt=Trapezius muscle (highlighted in green) - posterior view|right|frameless|400x400px|Trapezius muscle (highlighted in green) - posterior view]]
add text here related to databases searched, keywords, and search timeline <br>
Myalgia is generally known as a muscle ache or muscle pain.


== Definition/Description  ==
Trapezius myalgia (TM) is the complaint of pain, stiffness, and tightness of the upper trapezius muscle. It is characterised by acute or persistent neck-shoulder pain.<ref name=":9">De Meulemeester K, Calders P, De Pauw R, Grymonpon I, Govaerts A, Cagnie B. [https://www.ncbi.nlm.nih.gov/pubmed/28315581 Morphological and physiological differences in the upper trapezius muscle in patients with work-related trapezius myalgia compared to healthy controls: A systematic review]. Musculoskeletal Science and Practice. 2017 Jun 1;29:43-51.</ref><br>TM is not a medical disorder or disease but rather a symptom of an existing underlying condition. The pain in the muscle can last a few days or longer.


Trapezius Myalgia is chronic pain of the upper trapezius muscle, most frequent is neck pain. It is a complex and multifactorial condition. Musculoskeletal pain is often intensifying by mental and social stress at home or work. A biopsychosocial model plays an important role in the clinical management of chronic pain. It is a complex of different factors such neurobiological, psychological, coping styles, and contextual factors that contributes to the development and maintenance of chronic pain states12-13.<br>
Image: Trapezius muscle (highlighted in green) - posterior view<ref >Trapezius muscle (highlighted in green) - posterior view image - © Kenhub https://www.kenhub.com/en/library/anatomy/trapezius-muscle</ref>  


== Clinically Relevant Anatomy  ==
== Clinically Relevant Anatomy  ==
[[File:Muscles of the back superficial layer Primal.png|thumb|Trapezius muscle]]
[[Trapezius]] is a large fan-shaped muscle that extends from the cervical to thoracic region on the posterior aspect of the neck and trunk and attaches onto the clavicle and scapula.<ref>Simons SM, Dixon JB. Physical examination of the shoulder. Up-To-Date Online. 2013 Nov.</ref>


The trapezius muscle consists of 3 parts. <br>1. Trapezius pars descendens<br>2. Trapezius pars transversa<br>3. Trapezius pars ascendens
It consists of three parts with different actions:
* Superior fibres of Trapezius - elevates the shoulder girdle.  
* Middle fibres of Trapezius - retracts the scapula
* Inferior fibres of Trapezius - depresses the scapula
Typically the area of pain involved with TM is the superior fibres of the trapezius.  


It is the upper part of the muscle, Trapzius pars descendens, that is painfull. The origin is found on the external occipital protuberance, Nuchal ligament and spinonus processes of 7th cervical and all thoracic vertebrae. The insertion is on the lateral third of the clavicula and acromion and spine of the scapula.
== Aetiology/Epidemiology&nbsp;  ==


The function of the muscle is upward rotation of the glenoid cavity. The cranial fibers elevate the acromial end of the clavicula causing the glenoid cavity of the scapula to rotate upward (cranially).<br>Upward rotation of the scapula. <br>Extension of the head and to stabilize the scapula.<br>
Monotonous jobs with highly repetitive work, forceful exertions, high level of static contractions, prolonged static loads, constrained work postures or a combination of these factors are possible causes of neck and shoulder disorders (which include TM) in the working population. <ref name=":11">Larsson B, Søgaard K, Rosendal L. [https://www.ncbi.nlm.nih.gov/pubmed/17602993 Work-related neck/shoulder pain: a review on the magnitude, risk factors, biochemical characteristics, clinical picture, and preventive interventions.] Best Practice & Research Clinical Rheumatology. 2007 Jun 1;21(3):447-63.</ref>  


== Epidemiology /Etiology  ==
More research is required to conclude that computer work alone increases the risk of developing musculoskeletal disorders. <ref name=":14">Wærsted M, Hanvold TN, Veiersted KB. [https://www.ncbi.nlm.nih.gov/pubmed/20429925 Computer work and musculoskeletal disorders of the neck and upper extremity: a systematic review.] BMC musculoskeletal disorders. 2010 Dec;11(1):79.</ref><br>As recent research suggests with most musculoskeletal conditions there is a strong relationship between psychosocial factors and the occurrence of TM. There is some evidence that there is a link between TM and other social issues such as: lack of support from colleagues, mental stress at work and low influence.<ref name=":15">Burton AK. [https://journals.lww.com/spinejournal/Abstract/1997/11010/Back_Injury_and_Work_Loss__Biomechanical_and.21.aspx Back injury and work loss: biomechanical and psychosocial influences]. Spine. 1997 Nov 1;22(21):2575-80.</ref>


At the moment a large and increasing collection of epidemiologic findings has shown strong and consistent links between musculoskeletal disorders and several occupational ergonomic exposures like forceful exertions, highly repetitive motions, sustained static muscle loading, lack of sufficient rest, awkward body postures, localized mechanical stress and features of the work environment such as restrictive, high demand-low control jobs. However there is still less consensus about nature of the epidemiologic findings and the physical examination findings.
== Epidemiology ==


There has been done a lot of research on the aetiology of work related neck and shoulder disorders. Researchers agree that the disorders arise from both biomechanical and psychosocial factors. Within the biomechanical dimension the m. Trapezius plays an important role. This type of neck pain called ‘trapezius myalgia’ may be associated with a lot of changes. These changes can take place at both the peripheral and central level and can interact resulting in muscle pain and fatigue.2
Persistent TM concerns 10-20% of the 20% of the adult population with severe chronic pain in the neck and shoulder region. <ref>Gerdle B, Ghafouri B, Ernberg M, Larsson B. [https://www.ncbi.nlm.nih.gov/pubmed/24966693 Chronic musculoskeletal pain: a review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique]. Journal of pain research. 2014;7:313.</ref> The persistent form of TM also shows a higher prevalence in women, but also in low-income groups. <ref name=":0">Marker RJ, Balter JE, Nofsinger ML, Anton D, Fethke NB, Maluf KS. [https://www.ncbi.nlm.nih.gov/pubmed/26924036 Upper trapezius muscle activity in healthy office workers: reliability and sensitivity of occupational exposure measures to differences in sex and hand dominance]. Ergonomics. 2016 Sep 1;59(9):1205-14.</ref>


At the peripheral level the changes occur at the muscular level. There have been seen mitochondrial disturbances in the type I fibres and also reduced capillary density and circulation.5,7 These changes can possibly cause interferences in the oxidative metabolism of the muscles. There has also been described transformations of oxidative type I fibres to quick-acting glycolytic type IIb fibres.12 These changes can explain the muscle fatigue and pain. In one study they also found a larger cross-sectional area of the type I one fibres of the upper trapezius which demonstrates a higher load of these fibres.6
Gender seems to play an important role in the development of neck disorders since the prevalence is much higher among women. Women more often experience neck pain and develop persistent pain than men do. This difference might be explained by the content of their jobs. Women’s work tasks involve more static load on the neck muscles, high repetitiveness, low control, and high mental demands, which are all risk factors for developing neck disorders.<ref name=":0" />  
 
At the central level a reorganization of the neuromotor control strategies takes place. This can be illustrated in the cervical flexors by a dysfunction of the deeper flexors and a loss of force and endurance of these muscles.10 Persons with complaints also show a delayed activation of the muscles of the neck with arm movements.4 The superficial cervical flexors show a higher muscle activation and are faster fatigued, which demonstrate a less efficient function of the stabilization mechanism of the neck.3 This phenomenon is also seen in the cervical extensors where the superficial upper trapezius shows a higher activation then the erector spinae. Szeto et al. (2005) demonstrate in their study that the greater recruitment of type II fibres in symptomatic persons could possibly explain the muscle fatigue. These patients also show a diminished ability to relax the trapezius muscle after work.11 Another study showed a higher EMG-activity and an impaired relaxation time in symptomatic persons.9
 
Not only the biomechanical factors play an important role in het onset of trapezius myalgia. In the literature an causal relationship has been described between psychosocial factors and the occurrence of neck and shoulder disorders. There is some evidence for a link between disorders and high quantitative and qualitative demands, lack of support of colleagues, low job control and low influence.1 They also demonstrated a relationship between mental stress at work and disorders.11<br>&nbsp;<br>


== Characteristics/Clinical Presentation  ==
== Characteristics/Clinical Presentation  ==


The clinical presentation of Trapezius myalgia is chronic neck pain, pain, spasms and tenderness in the upper trapezius. The trigger points in the muscle results in painfull headarches behind the eye, into the temple and in the back of the neck.<br> <br><br>
Typical symptoms of “myalgia” are:
* Sudden onset of pain<ref name=":9" />
* Muscle stiffness and spasms<ref name=":9" />
* Tightness of the neck-shoulder complex<ref name=":9" />
* Heaviness of the head and occipital headache
* Tenderness of the upper trapezius area<ref name=":9" />
Other symptoms:
* Low mood<ref name=":19">Sjörs, A., Larsson, B., Persson, A. L., & Gerdle, B. (2011). ''An increased response to experimental muscle pain is related to psychological status in women with chronic non-traumatic neck-shoulder pain. BMC Musculoskeletal Disorders, 12(1).'' doi:10.1186/1471-2474-12-230</ref>
* Anxiety<ref name=":19" />
* Paresthesia<ref>Larsson, R., Öberg, Å. P., & Larsson, S.-E. (1999). ''Changes of trapezius muscle blood flow and electromyography in chronic neck pain due to trapezius myalgia. Pain, 79(1), 45–50.'' doi:10.1016/s0304-3959(98)00144-4 </ref>
Persistent TM can cause pain and stiffness after periods of inactivity. The pain usually eases after reasonable exercise.<ref name=":10">Waling K, Sundelin G, Ahlgren C, Järvholm B. [https://www.ncbi.nlm.nih.gov/pubmed/10692619 Perceived pain before and after three exercise programs–a controlled clinical trial of women with work-related trapezius myalgia.] Pain. 2000 Mar 1;85(1-2):201-7.</ref>


== Differential Diagnosis  ==
== Differential Diagnosis  ==


<br>
TM can be diagnosed when neck pain, muscle tightness, and trigger points are present, but tension neck syndrome or cervical syndrome is not present.<ref name=":11" />
 
Other pathologies that can cause similar symptoms are:
* Cervical spondylosis<ref name=":12">Pateder DB, Berg JH, Thal R. [https://europepmc.org/abstract/med/19995495 Neck and shoulder pain: differentiating cervical spine pathology from shoulder pathology]. Journal of surgical orthopaedic advances. 2009;18(4):170-4.</ref>
* [[Cervical Osteoarthritis|Cervical osteoarthritis]]
* [[Cervical Myelopathy|Cervical radiculopathy]]
* [[Thoracic Outlet Syndrome (TOS)|Thoracic Outlet Syndrome]]
* Shoulder pathology - including [[Rotator Cuff Tears|rotator cuff]] pathology and shoulder osteoarthritis<ref name=":13">Mitchell C, Adebajo A, Hay E, Carr A. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283277/#ref18 Shoulder pain: diagnosis and management in primary care.] BMJ: British Medical Journal. 2005 Nov 12;331(7525):1124.</ref>
* [[Polymyalgia Rheumatica|Polymyaglia rheumatica]]<ref name=":13" />  


== Diagnostic Procedures  ==
== Diagnostic Procedures  ==


The basis for diagnostic criteria of neck and shoulder myalgia is not very clear, and the diagnostic terminology and methods for assessment are variable. This indicates that several more or less specific and partly overlapping diagnoses exist. Progressing neck and shoulder pain accompanied with no other symptoms or signs (red flags) does not require specific investigations like radiography, magnetic resonance imaging, electromyography or nerve conductance testing. A standardized clinical examination for the clinical diagnosis of neck and shoulder myalgia contains questions on pain, tiredness and stiffness on the day of examination and physical tests. These test measure range of motion and tightness of muscles, pain threshold and sensitivity, muscle strength and palpation tender points.8 <br>Possible risk factors <br>In the review of Larsson et al. an overview is given of the possible risk factors for work-related upper-extremity disorders. The conclusion stated that strong evidence was found for a causal relationship between neck disorders and highly repetitive work, forceful exertions, high level of static contractions, prolonged static loads and extreme postures as well as combinations of these previously named factors. But there was insufficient evidence for vibration as a risk factor. Also gender seems to play an important role in the development of neck disorders, since the prevalence is much higher among women. This difference can possibly explained with the fact that women’s jobs involve more work tasks with static load on the neck muscles, high repetitiveness, low control and high mental demands which are all risk factors for developing neck-shoulder pain. After the biomechanical and individual factors there are also psychosocial factors that have a causal relationship with the occurrence of neck and shoulder disorders.8 There is some evidence for a link between disorders and high quantitative and qualitative demands, lack of support of colleagues, low job control and low influence. They also demonstrated a relationship between mental stress at work and disorders.1 <br>It seems logical, as we see all of the risk factors, that there is evidence for an increased risk for development of upper-extremity disorders among computer users. It was suggested that this could be due to constrained postures, constant force and highly repetitive movements as well as psychosocial factors such as time constraints and high quantitative demands.8 <br>
The basis for diagnostic criteria of neck and shoulder myalgia is not very clear and the diagnostic terminology and methods for assessment are variable.<ref name=":11" />
 
== Outcome Measures ==


add links to outcome measures here (also see [[Outcome Measures|Outcome Measures Database]])   
* Thorough subjective assessment
* Objective assessment - including neurological exam, and shoulder assessment
* Imaging studies - can be useful if no improvement in symptoms, neurological symptoms or if [[Red Flags in Spinal Conditions|red flags]] present<ref name=":12" />
* Use of diagnostic injections (if qualified to do so)<ref name=":12" />
* Referral to orthopaedic consultant if no improvement in symptoms with conservative management<ref name=":13" />  


== Examination  ==
In general, no objective diagnostic methods are available specifically for TM. The diagnosis is mostly based on symptom presentation and history of illness.


add text here related to physical examination and assessment<br>
== Outcome Measures  ==


== Medical Management <br> ==
[[Visual Analogue Scale|Visual analogue scale]]<ref name=":10" /><br>This scale measures visualises to what extend the patient experiences pain or another sensation. It is a 100mm line on which the patient need to draw a perpendicular line to indicate how he experiences pain. On the left is the minimum score of 0 meaning ‘no pain’ and on the right, stands the maximus score of 10, which means ‘unbearable pain’.<u></u><u></u><u></u><u></u><u></u><u></u><u></u><u></u><u></u><u></u><u></u><u></u>


add text here <br>  
[[McGill Pain Questionnaire|McGill pain questionnaire]] (MPQ)<ref>Hawker GA, Mian S, Kendzerska T, French M. [https://onlinelibrary.wiley.com/doi/full/10.1002/acr.20543 Measures of adult pain: Visual analog scale for pain (vas pain), numeric rating scale for pain (nrs pain), mcgill pain questionnaire (mpq), short‐form mcgill pain questionnaire (sf‐mpq), chronic pain grade scale (cpgs), short form‐36 bodily pain scale (sf‐36 bps), and measure of intermittent and constant osteoarthritis pain (icoap)]. Arthritis care & research. 2011 Nov 1;63(S11):S240-52.</ref> <ref>Melzack R. [https://www.researchgate.net/publication/21919681_The_McGill_Pain_Questionnaire_Major_Properties_and_Scoring_Methods The McGill Pain Questionnaire: major properties and scoring methods]. Pain. 1975 Sep 1;1(3):277-99.</ref> <ref name=":1">OHLSSON K, ATTEWELL RG, JOHNSSON B, AHLM A, Skerfving S. [https://www.ncbi.nlm.nih.gov/pubmed/8206057 An assessment of neck and upper extremity disorders by questionnaire and clinical examination]. Ergonomics. 1994 May 1;37(5):891-7.</ref><br>The MPQ is a subjective questionnaire used to asses the quality and intensity of pain in patients with a number of diagnoses.


== Physical Therapy Management <br> ==
[[Neck Disability Index|Neck disability index]] (NDI)&nbsp;<ref>Macdermid JC, Walton DM, Avery S, Blanchard A, Etruw E, Mcalpine C, Goldsmith CH. [https://www.ncbi.nlm.nih.gov/pubmed/19521015 Measurement properties of the neck disability index: a systematic review.] Journal of orthopaedic & sports physical therapy. 2009 May;39(5):400-C12.</ref><ref name=":2">Gay RE, Madson TJ, Cieslak KR. [https://www.ncbi.nlm.nih.gov/pubmed/17509434 Comparison of the Neck Disability Index and the Neck Bournemouth Questionnaire in a sample of patients with chronic uncomplicated neck pain]. Journal of Manipulative and Physiological Therapeutics. 2007 May 1;30(4):259-62.</ref> <ref name=":1" /><br>The NDI is a questionnaire that inquires the functional status of a patient concern the following 10 items: pain, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation.


• Biofeedback<br>• Specific Strength training: 1-arm row, shoulder abduction, shoulder elevation, reverse flies and upward row.<br>• General endurance training<br>• Manual techniques: ischemic compression, transverse friction massage, stretching<br>• Tens<br>• Laser therapie<br>Prevention:<br>Prolonged stress in the upper trapezius muscle can activate latent trigger points or maintain pain in active trigger points. Biofeedback in the form of EMG of the upper trapezius muscle during work leeds to significant less activity and more rest pauses of the specific muscle. Therefore biofeedback might be useful in the treatment of trapezius myalgia. (Holtermann et al, 2008; level 1B)
[[The Bournemouth Questionnaire|Neck Bournemouth Questionnaire]] (NBQ)<ref name=":3">Bolton JE, Humphreys BK. [https://www.ncbi.nlm.nih.gov/pubmed/11986574 The Bournemouth Questionnaire: a short-form comprehensive outcome measure. II. Psychometric properties in neck pain patients.] Journal of manipulative and physiological therapeutics. 2002 Mar 1;25(3):141-8.</ref> <ref name=":2" /> <ref name=":1" /><br>The NBQ is administered to patients with non-specific neck pain. It assesses pain, disability, effective and cognitive aspects of the neck pain.&nbsp;The questionnaire contains seven items: pain intensity, function in activities of daily living, function in social activities, anxiety, depression levels and fear avoidance behaviour. The NBQ has been shown to be reliable, valid, and responsive to clinically significant change in patients with non-specific neck pain.<ref name=":3" />


Physical exercise:<br>Exercise seems to have beneficial effects on patients suffering from work related trapezius myalgia. Both general fitness training and specific strength training generate significant effects on diminishing pain. However strength training has proven to be even more effective compared to general fitness training. Prolonged effects 10 weeks after intervention were found (Andersen et al., 2008; level 1B). Other studies noted that long-term effects after 3 years disappeared. (Waling et al., 2002; level 1B)
== Examination  ==
 
Manual therapies:<br>Ischemic compression, stretch of the upper trapezius muscle, transverse friction massage are manual techniques to help patients with trapezius myalgia. These techniques appear to have instant improvement on pain. Long-term effects have not yet been well investigated. (De Las Penas et al., 2005; Level 1A)


Physical applications:<br>Transcutaneous Electro Nerve Stimulation (TENS) and laser therapy seemed to have positive short-term effects. However, more investigation on the long-term effect of these applications are needed. Also the most efficient type, frequency and duration of laser therapy require additional research. (Vernon &amp; Schneider, 2009; level 1A)<br><br>
Subjective assessment is vital in assessing the condition history, potential cause and severity. It is also necessary in order to assess the patient's outlook and mental well being, which is a good indicator for prognosis and recovery in all types of injury or illness.<ref>Chida Y, Steptoe A. [https://journals.lww.com/psychosomaticmedicine/Abstract/2008/09000/Positive_Psychological_Well_Being_and_Mortality__A.1.aspx Positive psychological well-being and mortality: a quantitative review of prospective observational studies.] Psychosomatic medicine. 2008 Sep 1;70(7):741-56.</ref>


== Key Research  ==
Outcome measures can be used at the initial assessment to indicate severity and impact on the patient's well being and quality of life (as noted in the Outcome measures section).


add links and reviews of high quality evidence here (case studies should be added on new pages using the [[Template:Case Study|case study template]])<br>  
Objective examination of the neck and upper extremities can be useful for diagnosing TM or exclude other pathologies. This should include:
# Cervical and shoulder range of movement (active and passive)
# Muscle strength
# Palpation
# Neurological exam <ref name=":4">Sjøgaard G, Søgaard K, Hermens HJ, Sandsjö L, Läubli T, Thorn S, Vollenbroek-Hutten MM, Sell L, Christensen H, Klipstein A, Kadefors R. [https://www.ncbi.nlm.nih.gov/pubmed/16193340 Neuromuscular assessment in elderly workers with and without work-related shoulder/neck trouble: the NEW-study design and physiological findings.] European Journal of Applied Physiology. 2006 Jan 1;96(2):110-21.</ref>  


== Resources <br> ==
Patients suffering from TM can present with neck pain, headaches, tightness of the trapezius muscle and palpable trigger points.<ref name=":4" /> <ref name=":5">Hadrevi J, Ghafouri B, Larsson B, Gerdle B, Hellström F. [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073285 Multivariate modeling of proteins related to trapezius myalgia, a comparative study of female cleaners with or without pain]. PLOS one. 2013 Sep 4;8(9):e73285.</ref>  


add appropriate resources here <br>  
A surface electromyography can be done to evaluate muscle function. Parameters that can be studied are amplitude, timing, conduction velocity, fatigability and characteristic frequencies/patterns.<ref>Castelein B, Cools A, Bostyn E, Delemarre J, Lemahieu T, Cagnie B. [https://www.ncbi.nlm.nih.gov/pubmed/25683111 Analysis of scapular muscle EMG activity in patients with idiopathic neck pain: a systematic review]. Journal of Electromyography and Kinesiology. 2015 Apr 1;25(2):371-86.</ref>


== Clinical Bottom Line ==
== Medical Management ==
 
* Analgesia
add text here <br>  
* Ergonomic advice<ref name=":17">Holtermann A, Søgaard K, Christensen H, Dahl B, Blangsted AK. [https://www.ncbi.nlm.nih.gov/pubmed/18704481 The influence of biofeedback training on trapezius activity and rest during occupational computer work: a randomized controlled trial.] European journal of applied physiology. 2008 Dec 1;104(6):983-9.</ref>
 
* Referral to physiotherapy<ref name=":16" />
== Recent Related Research (from [http://www.ncbi.nlm.nih.gov/pubmed/ Pubmed]) ==
* Injection therapy<ref name=":16" />
 
* Radiofrequency denervation<ref name=":16" />
see tutorial on [[Adding PubMed Feed|Adding PubMed Feed]]
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== References  ==


1. Ariëns A.M. et al., High Quantitative Job Demands and Low Coworker Support As Risk Factors for Neck Pain., 2001, Spine, 26, 1896–1903. (2B)
== Physical Therapy Management    ==


2. Falla D. Et al., An electromyographic analysis of the deep cervical flexor muscles in performance of craniocervical flexion., 2003, Physical Therapy, 83(10), 899-906. (1B)
=== Prevention ===


3. Falla D. et al., Feedforward activity of the cercvical flexor muscles during voluntary arm movements is delayed in chronic neck pain., 2004, Experimental Brain Research, 157(1), 43-48. (2B)
Raising awareness for at risk groups of people:<ref name=":16" />
* Repetitive movement jobs<ref name=":11" /> 
* Sedentary jobs (computer work)<ref name=":14" /> 
* High work demands 
* Work posture 
* Vibration 
* Stress<ref name=":15" />
* Low activity level outside of work<ref name=":16" />
* Gender (women)<ref name=":0" /> 


4. Hägg G.M. et al., Human muscle fibre abnormalities related to occupational load., European Journal of Applied Physiology, 2000, 83(2-3), 159-165. (1A)
=== Exercise Therapy ===


5. Kadi F. et al., Pathological mechanisms implicated in localized female trapeziusmyalgia ., Pain, 1998, 78, 191-196. (2B)
Different forms of exercise is recommended for acute or persistent neck pain. <ref name=":16">Jensen, IreneHarms-Ringdahl, Karin et al. [https://www.ncbi.nlm.nih.gov/pubmed/17350546 Strategies for prevention and management of musculoskeletal conditions. Neck pain]. Best Practice & Research Clinical Rheumatology , 2007 Feb;21(1):93-108.</ref>


6. Larsson B. et al., Blood supply and oxidative metabolism in muscle biopsies of female cleaners with and without myalgie., Clinical Journal of Pain, 2004, 20(6), 440-446. (2B)  
Physical activity and exercise have been proven to give the most immediate and long-term pain relief in patients with TM<ref>Nielsen PK, Andersen LL, Olsen HB, Rosendal L, Sjøgaard G, Søgaard K. [https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.21577 Effect of physical training on pain sensitivity and trapezius muscle morphology.] Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine. 2010 Jun;41(6):836-44.</ref>. Both general fitness training and specific strength training generate significant effects on decreasing pain<ref name=":6">Andersen LL, Kjaer M, SØgaard K, Hansen L, Kryger AI, Sjögaard G. [https://www.ncbi.nlm.nih.gov/pubmed/18163419 Effect of two contrasting types of physical exercise on chronic neck muscle pain]. Arthritis Care & Research: Official Journal of the American College of Rheumatology. 2008 Jan;59(1):84-91.</ref>. However; strength training has been proven to be more effective compared to general fitness training.


7. Larsson et al., Work related neck-shoulder pain: a review on magnitude, risk factors, biochemical characteristics, clinical picture and preventive interventions, Best practice and research clinical rheumatology, 2007, 21(3), 447-463. (1A)
High-intensity strength training relying on principles of progressive overload for 20 minutes has been shown to be successful in reductions of neck and shoulder pain.<ref>Rodrigues EV, Gomes AR, Tanhoffer AI, Leite N. [https://www.ncbi.nlm.nih.gov/pubmed/25538482 Effects of exercise on pain of musculoskeletal disorders: a systematic review]. Acta ortopedica brasileira. 2014 Dec;22(6):334-8.</ref> <ref>Hagberg M, Harms-Ringdahl K, Nisell R, Hjelm EW. [https://www.ncbi.nlm.nih.gov/pubmed/10943754 Rehabilitation of neck-shoulder pain in women industrial workers: a randomized trial comparing isometric shoulder endurance training with isometric shoulder strength training.] Archives of physical medicine and rehabilitation. 2000 Aug 1;81(8):1051-8.</ref><ref>Zebis MK, Andersen LL, Pedersen MT, Mortensen P, Andersen CH, Pedersen MM, Boysen M, Roessler KK, Hannerz H, Mortensen OS, Sjøgaard G. [https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/1471-2474-12-205 Implementation of neck/shoulder exercises for pain relief among industrial workers: a randomized controlled trial.] BMC musculoskeletal disorders. 2011 Dec;12(1):205.</ref>


8. Nederhand M.J. et al., Cervical muscle dysfunction in the chronic whiplash associated disorder grade II (WAD-II)., 2000, Spine, 25(15), 1938-43.9. (2B)
Following a specific neck strengthening exercise program for up to 1 year can lead to long term reduction and further prevention of recurring pain even after the strength program has ceased.<ref>Ylinen J, Hakkinen A, Nykanen M, Kautiainen H, Takala E. [https://www.researchgate.net/publication/6306644_Neck_muscle_training_in_the_treatment_of_chronic_neck_pain_A_three-year_follow-up_study Neck muscle training in the treatment of chronic neck pain: a three-year follow-up study]. Europa medicophysica. 2007 Jun 1;43(2):161.</ref>
# Shoulder shrugs: <br>The subject is standing erect and holding the dumbbells to the side, then elevates the shoulders while focusing on contracting the upper trapezius muscle.
# One-arm row: <br>The subject bends their torso forward to approximately 30° from horizontal with one knee on the bench and the other foot on the floor. The subject now pulls the dumbbell towards the ipsilateral lower rib, while the contralateral arm is maintained extended and supports the body on the bench.
# Upright row: <br>The subject is standing erect and holding the dumbbells while the arms are hanging relaxed in front of the body. The dumbbells are lifted towards the chest in a vertical line close to the body while flexing the elbows and abducting the shoulder. The elbows are pointing out- and upwards.
# Reverse flies: <br>The subject is prone on a bench at a 45° angle from horizontal and the arms pointing towards the floor. The dumbbells are raised until the upper arm is horizontal, while the elbows are in a static slightly flexed position (~5°) during the entire range of motion.
# Lateral raise:<br>The subject is standing erect and holding the dumbbells by their side, and then abducts the shoulder joint until the upper arm is horizontal. The elbows are in a static slightly flexed position (5°) during the entire range of motion.
Exercise has been shown to increase blood flow and therefore oxygenation to areas of the body with increased anaerobic muscle metabolism. <ref>Andersen LL, Blangsted AK, Nielsen PK, Hansen L, Vedsted P, Sjøgaard G, Søgaard K. [https://www.ncbi.nlm.nih.gov/pubmed/20512501 Effect of cycling on oxygenation of relaxed neck/shoulder muscles in women with and without chronic pain]. European journal of applied physiology. 2010 Sep 1;110(2):389-94.</ref> 


9. Silverman J.L. et al., Quantitative cervical flexor strength in healthy subjects and in subjects with mechanical neck pain., 1991, Archives of Physical and Medical Rehabilitation, 72(9), 679-681. (2B)
=== Psychosocial involvement ===
The possible presence of psychosocial causative factors in patients with TM should be considered from the outset. Explanation of pain and the influence of psychosocial factors should also be included in the treatment of TM alongside exercise therapy. <ref name=":15" />


10. Szeto G. Et al., A comparison of symptomatic and asymptomatic office workers performing monotonous keyboard work- 1: neck and shoulder muscle recruitment patterns., 2005, Manual Therapy, 10, 270-280.
=== Manual Therapy ===


11. Uhlig Y. et al., Fiber composition and fiber transformations in neck muscles of patients with dysfunction of the cervical spine. Journal of Orthopedic Research, 1995, 13(2), 240-249. (2B)
There is moderate evidence available for short-term relief of myofascial trigger points by [[Transcutaneous Electrical Nerve Stimulation (TENS)|Transcutaneous Electro Nerve Stimulation]] (TENS), [[acupuncture]] and magnet or laser therapy.<ref name=":8">Vernon H, Schneider M. [https://www.ncbi.nlm.nih.gov/pubmed/19121461 Chiropractic management of myofascial trigger points and myofascial pain syndrome: a systematic review of the literature.] Journal of manipulative and physiological therapeutics. 2009 Jan 1;32(1):14-24. </ref><ref>Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM. [https://www.ncbi.nlm.nih.gov/pubmed/19913903 Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials]. The Lancet. 2009 Dec 5;374(9705):1897-908.</ref>


12. Anna Sjörs, Physiological responses to low-force work and psychosocial stress in women with chronic trapezius myalgia, BioMed Central, 2009 (1A)
Some studies have shown that in the short term acupuncture/dry needling can have the largest effect on pain. There is no evidence of effective treatment to reduce pain in the intermediate and long term periods.<ref name=":7">Nunes AM, Moita JP. [https://www.journalofosteopathicmedicine.com/article/S1746-0689(15)00017-6/abstract Effectiveness of physical and rehabilitation techniques in reducing pain in chronic trapezius myalgia: A systematic review and meta-analysis]. International Journal of Osteopathic Medicine. 2015 Sep 30;18(3):189-206.</ref>


13. Ghafouri N., High levels of N-palmitoylethanolamide and N-stearoylethanolamide in microdialysate samples from myalgic trapezius muscle in women, PLOS-one 2011;6(11):e27257 (2B)
There is conflicting evidence as to whether ultrasound therapy is no more effective than a placebo or somewhat more effective than other therapies in the treatment of myofascial trigger points. Ultrasound can therefore be used as a therapeutic modulation, but is not recommended.<ref name=":8" /> 


14. Vernon H, Schneider M., Chiropractic management of myofascial trigger points and myofascial pain syndrome: a systematic review of the literature., J Manipulative Physiol Ther. 2009 Jan;32(1):14-24. Level of evidence (1A)
Biofeedback training can also be useful in the treatment of work-related neck and shoulder pain. A study has shown that six weeks of biofeedback training resulted in less pain and neck disability than active and passive treatment, which remained at 6 months post-intervention in the control.<ref name=":17" /> <ref name=":18">Aguilera FJ, Martín DP, Masanet RA, Botella AC, Soler LB, Morell FB. [https://www.ncbi.nlm.nih.gov/pubmed/19748402 Immediate effect of ultrasound and ischemic compression techniques for the treatment of trapezius latent myofascial trigger points in healthy subjects: a randomized controlled study.] Journal of manipulative and physiological therapeutics. 2009 Sep 1;32(7):515-20.</ref><ref name=":8" />


15. De las penas, C.F., Campo, M.S., Carnero, J.F., Page, J.C., Manual therapies in myofascial triggerpoint treatment: a systematic review., journal of Body work and Movement Therapies (2005) 9,27–34. Level of evidence (1A)
Ischaemic compression, stretching of the upper trapezius muscle, and transverse friction massage are manual techniques to help patients with TM. These techniques appear to have instant improvement on pain. Long-term effects have not yet been well investigated.<ref name=":8" /><ref name=":18" /><sup></sup>


16. Holtermann A, Søgaard K, Christensen H, Dahl B, Blangsted AK., The influence of biofeedback training on trapezius activity and rest during occupational computer work: a randomized controlled trial., Eur J Appl Physiol. 2008 Dec;104(6):983-9. Level of evidence (1B)
== Clinical Bottom Line ==
Trapezius Myalgia is rather a symptom of an underlying problem than the problem itself and is often categorised with neck and shoulder disorders<ref name=":13" />. The typical symptom of a patient with TM is pain in the upper fibers of trapezius that can linger for a few days to weeks but can also be persistent in nature. This pain is often associated with spasms, stiffness, and tenderness in the neck region. Trigger points can also be present and can cause headaches.


17. Andersen LL, Kjaer M, Søgaard K, Hansen L, Kryger AI, Sjøgaard G., Effect of two contrasting types of physical exercise on chronic neck muscle pain., Arthritis Rheum. 2008 Jan 15;59(1):84-91. Level of evidence (1B)
Both biomechanical and psychosocial factors can contribute to the development and persistence of TM.<br>Radiography, MRI, electromyography, nerve conduction studies or blood tests could be done to rule out other conditions, but are not standard procedure.  


18. Waling K, Järvholm B, Sundelin G., Effects of training on female trapezius Myalgia: An intervention study with a 3-year follow-up period., Spine (Phila Pa 1976). 2002 Apr 15;27(8):789-96. Level of evidence (1B)
Physiotherapy is the main treatment method and exercise therapy is highly recommended including healthy lifestyle advice. In conjunction with an exercise program, manual therapy can be used for short term benefits in pain relief.  


== Resources ==


This 2-minute video is a good overview of the trapezius muscle.<ref > Trapezius muscle image - © Kenhub https://www.kenhub.com/en/library/anatomy/trapezius-muscle</ref> {{#ev:youtube|dCjs-Nshn7A}}




== References  ==
<references />


<br><br>
[[Category:Conditions]]

Latest revision as of 20:45, 17 March 2023

Definition/Description[edit | edit source]

Trapezius muscle (highlighted in green) - posterior view

Myalgia is generally known as a muscle ache or muscle pain.

Trapezius myalgia (TM) is the complaint of pain, stiffness, and tightness of the upper trapezius muscle. It is characterised by acute or persistent neck-shoulder pain.[1]
TM is not a medical disorder or disease but rather a symptom of an existing underlying condition. The pain in the muscle can last a few days or longer.

Image: Trapezius muscle (highlighted in green) - posterior view[2]

Clinically Relevant Anatomy[edit | edit source]

Trapezius muscle

Trapezius is a large fan-shaped muscle that extends from the cervical to thoracic region on the posterior aspect of the neck and trunk and attaches onto the clavicle and scapula.[3]

It consists of three parts with different actions:

  • Superior fibres of Trapezius - elevates the shoulder girdle.
  • Middle fibres of Trapezius - retracts the scapula
  • Inferior fibres of Trapezius - depresses the scapula

Typically the area of pain involved with TM is the superior fibres of the trapezius.

Aetiology/Epidemiology [edit | edit source]

Monotonous jobs with highly repetitive work, forceful exertions, high level of static contractions, prolonged static loads, constrained work postures or a combination of these factors are possible causes of neck and shoulder disorders (which include TM) in the working population. [4]

More research is required to conclude that computer work alone increases the risk of developing musculoskeletal disorders. [5]
As recent research suggests with most musculoskeletal conditions there is a strong relationship between psychosocial factors and the occurrence of TM. There is some evidence that there is a link between TM and other social issues such as: lack of support from colleagues, mental stress at work and low influence.[6]

Epidemiology[edit | edit source]

Persistent TM concerns 10-20% of the 20% of the adult population with severe chronic pain in the neck and shoulder region. [7] The persistent form of TM also shows a higher prevalence in women, but also in low-income groups. [8]

Gender seems to play an important role in the development of neck disorders since the prevalence is much higher among women. Women more often experience neck pain and develop persistent pain than men do. This difference might be explained by the content of their jobs. Women’s work tasks involve more static load on the neck muscles, high repetitiveness, low control, and high mental demands, which are all risk factors for developing neck disorders.[8]

Characteristics/Clinical Presentation[edit | edit source]

Typical symptoms of “myalgia” are:

  • Sudden onset of pain[1]
  • Muscle stiffness and spasms[1]
  • Tightness of the neck-shoulder complex[1]
  • Heaviness of the head and occipital headache
  • Tenderness of the upper trapezius area[1]

Other symptoms:

Persistent TM can cause pain and stiffness after periods of inactivity. The pain usually eases after reasonable exercise.[11]

Differential Diagnosis[edit | edit source]

TM can be diagnosed when neck pain, muscle tightness, and trigger points are present, but tension neck syndrome or cervical syndrome is not present.[4]

Other pathologies that can cause similar symptoms are:

Diagnostic Procedures[edit | edit source]

The basis for diagnostic criteria of neck and shoulder myalgia is not very clear and the diagnostic terminology and methods for assessment are variable.[4]

  • Thorough subjective assessment
  • Objective assessment - including neurological exam, and shoulder assessment
  • Imaging studies - can be useful if no improvement in symptoms, neurological symptoms or if red flags present[12]
  • Use of diagnostic injections (if qualified to do so)[12]
  • Referral to orthopaedic consultant if no improvement in symptoms with conservative management[13]

In general, no objective diagnostic methods are available specifically for TM. The diagnosis is mostly based on symptom presentation and history of illness.

Outcome Measures[edit | edit source]

Visual analogue scale[11]
This scale measures visualises to what extend the patient experiences pain or another sensation. It is a 100mm line on which the patient need to draw a perpendicular line to indicate how he experiences pain. On the left is the minimum score of 0 meaning ‘no pain’ and on the right, stands the maximus score of 10, which means ‘unbearable pain’.

McGill pain questionnaire (MPQ)[14] [15] [16]
The MPQ is a subjective questionnaire used to asses the quality and intensity of pain in patients with a number of diagnoses.

Neck disability index (NDI) [17][18] [16]
The NDI is a questionnaire that inquires the functional status of a patient concern the following 10 items: pain, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation.

Neck Bournemouth Questionnaire (NBQ)[19] [18] [16]
The NBQ is administered to patients with non-specific neck pain. It assesses pain, disability, effective and cognitive aspects of the neck pain. The questionnaire contains seven items: pain intensity, function in activities of daily living, function in social activities, anxiety, depression levels and fear avoidance behaviour. The NBQ has been shown to be reliable, valid, and responsive to clinically significant change in patients with non-specific neck pain.[19]

Examination[edit | edit source]

Subjective assessment is vital in assessing the condition history, potential cause and severity. It is also necessary in order to assess the patient's outlook and mental well being, which is a good indicator for prognosis and recovery in all types of injury or illness.[20]

Outcome measures can be used at the initial assessment to indicate severity and impact on the patient's well being and quality of life (as noted in the Outcome measures section).

Objective examination of the neck and upper extremities can be useful for diagnosing TM or exclude other pathologies. This should include:

  1. Cervical and shoulder range of movement (active and passive)
  2. Muscle strength
  3. Palpation
  4. Neurological exam [21]

Patients suffering from TM can present with neck pain, headaches, tightness of the trapezius muscle and palpable trigger points.[21] [22]

A surface electromyography can be done to evaluate muscle function. Parameters that can be studied are amplitude, timing, conduction velocity, fatigability and characteristic frequencies/patterns.[23]

Medical Management[edit | edit source]

  • Analgesia
  • Ergonomic advice[24]
  • Referral to physiotherapy[25]
  • Injection therapy[25]
  • Radiofrequency denervation[25]

Physical Therapy Management[edit | edit source]

Prevention[edit | edit source]

Raising awareness for at risk groups of people:[25]

  • Repetitive movement jobs[4]
  • Sedentary jobs (computer work)[5]
  • High work demands
  • Work posture
  • Vibration
  • Stress[6]
  • Low activity level outside of work[25]
  • Gender (women)[8]

Exercise Therapy[edit | edit source]

Different forms of exercise is recommended for acute or persistent neck pain. [25]

Physical activity and exercise have been proven to give the most immediate and long-term pain relief in patients with TM[26]. Both general fitness training and specific strength training generate significant effects on decreasing pain[27]. However; strength training has been proven to be more effective compared to general fitness training.

High-intensity strength training relying on principles of progressive overload for 20 minutes has been shown to be successful in reductions of neck and shoulder pain.[28] [29][30]

Following a specific neck strengthening exercise program for up to 1 year can lead to long term reduction and further prevention of recurring pain even after the strength program has ceased.[31]

  1. Shoulder shrugs:
    The subject is standing erect and holding the dumbbells to the side, then elevates the shoulders while focusing on contracting the upper trapezius muscle.
  2. One-arm row:
    The subject bends their torso forward to approximately 30° from horizontal with one knee on the bench and the other foot on the floor. The subject now pulls the dumbbell towards the ipsilateral lower rib, while the contralateral arm is maintained extended and supports the body on the bench.
  3. Upright row:
    The subject is standing erect and holding the dumbbells while the arms are hanging relaxed in front of the body. The dumbbells are lifted towards the chest in a vertical line close to the body while flexing the elbows and abducting the shoulder. The elbows are pointing out- and upwards.
  4. Reverse flies:
    The subject is prone on a bench at a 45° angle from horizontal and the arms pointing towards the floor. The dumbbells are raised until the upper arm is horizontal, while the elbows are in a static slightly flexed position (~5°) during the entire range of motion.
  5. Lateral raise:
    The subject is standing erect and holding the dumbbells by their side, and then abducts the shoulder joint until the upper arm is horizontal. The elbows are in a static slightly flexed position (5°) during the entire range of motion.

Exercise has been shown to increase blood flow and therefore oxygenation to areas of the body with increased anaerobic muscle metabolism. [32]

Psychosocial involvement[edit | edit source]

The possible presence of psychosocial causative factors in patients with TM should be considered from the outset. Explanation of pain and the influence of psychosocial factors should also be included in the treatment of TM alongside exercise therapy. [6]

Manual Therapy[edit | edit source]

There is moderate evidence available for short-term relief of myofascial trigger points by Transcutaneous Electro Nerve Stimulation (TENS), acupuncture and magnet or laser therapy.[33][34]

Some studies have shown that in the short term acupuncture/dry needling can have the largest effect on pain. There is no evidence of effective treatment to reduce pain in the intermediate and long term periods.[35]

There is conflicting evidence as to whether ultrasound therapy is no more effective than a placebo or somewhat more effective than other therapies in the treatment of myofascial trigger points. Ultrasound can therefore be used as a therapeutic modulation, but is not recommended.[33]

Biofeedback training can also be useful in the treatment of work-related neck and shoulder pain. A study has shown that six weeks of biofeedback training resulted in less pain and neck disability than active and passive treatment, which remained at 6 months post-intervention in the control.[24] [36][33]

Ischaemic compression, stretching of the upper trapezius muscle, and transverse friction massage are manual techniques to help patients with TM. These techniques appear to have instant improvement on pain. Long-term effects have not yet been well investigated.[33][36]

Clinical Bottom Line[edit | edit source]

Trapezius Myalgia is rather a symptom of an underlying problem than the problem itself and is often categorised with neck and shoulder disorders[13]. The typical symptom of a patient with TM is pain in the upper fibers of trapezius that can linger for a few days to weeks but can also be persistent in nature. This pain is often associated with spasms, stiffness, and tenderness in the neck region. Trigger points can also be present and can cause headaches.

Both biomechanical and psychosocial factors can contribute to the development and persistence of TM.
Radiography, MRI, electromyography, nerve conduction studies or blood tests could be done to rule out other conditions, but are not standard procedure.

Physiotherapy is the main treatment method and exercise therapy is highly recommended including healthy lifestyle advice. In conjunction with an exercise program, manual therapy can be used for short term benefits in pain relief.

Resources[edit | edit source]

This 2-minute video is a good overview of the trapezius muscle.[37]


References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 1.4 De Meulemeester K, Calders P, De Pauw R, Grymonpon I, Govaerts A, Cagnie B. Morphological and physiological differences in the upper trapezius muscle in patients with work-related trapezius myalgia compared to healthy controls: A systematic review. Musculoskeletal Science and Practice. 2017 Jun 1;29:43-51.
  2. Trapezius muscle (highlighted in green) - posterior view image - © Kenhub https://www.kenhub.com/en/library/anatomy/trapezius-muscle
  3. Simons SM, Dixon JB. Physical examination of the shoulder. Up-To-Date Online. 2013 Nov.
  4. 4.0 4.1 4.2 4.3 Larsson B, Søgaard K, Rosendal L. Work-related neck/shoulder pain: a review on the magnitude, risk factors, biochemical characteristics, clinical picture, and preventive interventions. Best Practice & Research Clinical Rheumatology. 2007 Jun 1;21(3):447-63.
  5. 5.0 5.1 Wærsted M, Hanvold TN, Veiersted KB. Computer work and musculoskeletal disorders of the neck and upper extremity: a systematic review. BMC musculoskeletal disorders. 2010 Dec;11(1):79.
  6. 6.0 6.1 6.2 Burton AK. Back injury and work loss: biomechanical and psychosocial influences. Spine. 1997 Nov 1;22(21):2575-80.
  7. Gerdle B, Ghafouri B, Ernberg M, Larsson B. Chronic musculoskeletal pain: a review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique. Journal of pain research. 2014;7:313.
  8. 8.0 8.1 8.2 Marker RJ, Balter JE, Nofsinger ML, Anton D, Fethke NB, Maluf KS. Upper trapezius muscle activity in healthy office workers: reliability and sensitivity of occupational exposure measures to differences in sex and hand dominance. Ergonomics. 2016 Sep 1;59(9):1205-14.
  9. 9.0 9.1 Sjörs, A., Larsson, B., Persson, A. L., & Gerdle, B. (2011). An increased response to experimental muscle pain is related to psychological status in women with chronic non-traumatic neck-shoulder pain. BMC Musculoskeletal Disorders, 12(1). doi:10.1186/1471-2474-12-230
  10. Larsson, R., Öberg, Å. P., & Larsson, S.-E. (1999). Changes of trapezius muscle blood flow and electromyography in chronic neck pain due to trapezius myalgia. Pain, 79(1), 45–50. doi:10.1016/s0304-3959(98)00144-4 
  11. 11.0 11.1 Waling K, Sundelin G, Ahlgren C, Järvholm B. Perceived pain before and after three exercise programs–a controlled clinical trial of women with work-related trapezius myalgia. Pain. 2000 Mar 1;85(1-2):201-7.
  12. 12.0 12.1 12.2 Pateder DB, Berg JH, Thal R. Neck and shoulder pain: differentiating cervical spine pathology from shoulder pathology. Journal of surgical orthopaedic advances. 2009;18(4):170-4.
  13. 13.0 13.1 13.2 13.3 Mitchell C, Adebajo A, Hay E, Carr A. Shoulder pain: diagnosis and management in primary care. BMJ: British Medical Journal. 2005 Nov 12;331(7525):1124.
  14. Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual analog scale for pain (vas pain), numeric rating scale for pain (nrs pain), mcgill pain questionnaire (mpq), short‐form mcgill pain questionnaire (sf‐mpq), chronic pain grade scale (cpgs), short form‐36 bodily pain scale (sf‐36 bps), and measure of intermittent and constant osteoarthritis pain (icoap). Arthritis care & research. 2011 Nov 1;63(S11):S240-52.
  15. Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975 Sep 1;1(3):277-99.
  16. 16.0 16.1 16.2 OHLSSON K, ATTEWELL RG, JOHNSSON B, AHLM A, Skerfving S. An assessment of neck and upper extremity disorders by questionnaire and clinical examination. Ergonomics. 1994 May 1;37(5):891-7.
  17. Macdermid JC, Walton DM, Avery S, Blanchard A, Etruw E, Mcalpine C, Goldsmith CH. Measurement properties of the neck disability index: a systematic review. Journal of orthopaedic & sports physical therapy. 2009 May;39(5):400-C12.
  18. 18.0 18.1 Gay RE, Madson TJ, Cieslak KR. Comparison of the Neck Disability Index and the Neck Bournemouth Questionnaire in a sample of patients with chronic uncomplicated neck pain. Journal of Manipulative and Physiological Therapeutics. 2007 May 1;30(4):259-62.
  19. 19.0 19.1 Bolton JE, Humphreys BK. The Bournemouth Questionnaire: a short-form comprehensive outcome measure. II. Psychometric properties in neck pain patients. Journal of manipulative and physiological therapeutics. 2002 Mar 1;25(3):141-8.
  20. Chida Y, Steptoe A. Positive psychological well-being and mortality: a quantitative review of prospective observational studies. Psychosomatic medicine. 2008 Sep 1;70(7):741-56.
  21. 21.0 21.1 Sjøgaard G, Søgaard K, Hermens HJ, Sandsjö L, Läubli T, Thorn S, Vollenbroek-Hutten MM, Sell L, Christensen H, Klipstein A, Kadefors R. Neuromuscular assessment in elderly workers with and without work-related shoulder/neck trouble: the NEW-study design and physiological findings. European Journal of Applied Physiology. 2006 Jan 1;96(2):110-21.
  22. Hadrevi J, Ghafouri B, Larsson B, Gerdle B, Hellström F. Multivariate modeling of proteins related to trapezius myalgia, a comparative study of female cleaners with or without pain. PLOS one. 2013 Sep 4;8(9):e73285.
  23. Castelein B, Cools A, Bostyn E, Delemarre J, Lemahieu T, Cagnie B. Analysis of scapular muscle EMG activity in patients with idiopathic neck pain: a systematic review. Journal of Electromyography and Kinesiology. 2015 Apr 1;25(2):371-86.
  24. 24.0 24.1 Holtermann A, Søgaard K, Christensen H, Dahl B, Blangsted AK. The influence of biofeedback training on trapezius activity and rest during occupational computer work: a randomized controlled trial. European journal of applied physiology. 2008 Dec 1;104(6):983-9.
  25. 25.0 25.1 25.2 25.3 25.4 25.5 Jensen, IreneHarms-Ringdahl, Karin et al. Strategies for prevention and management of musculoskeletal conditions. Neck pain. Best Practice & Research Clinical Rheumatology , 2007 Feb;21(1):93-108.
  26. Nielsen PK, Andersen LL, Olsen HB, Rosendal L, Sjøgaard G, Søgaard K. Effect of physical training on pain sensitivity and trapezius muscle morphology. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine. 2010 Jun;41(6):836-44.
  27. Andersen LL, Kjaer M, SØgaard K, Hansen L, Kryger AI, Sjögaard G. Effect of two contrasting types of physical exercise on chronic neck muscle pain. Arthritis Care & Research: Official Journal of the American College of Rheumatology. 2008 Jan;59(1):84-91.
  28. Rodrigues EV, Gomes AR, Tanhoffer AI, Leite N. Effects of exercise on pain of musculoskeletal disorders: a systematic review. Acta ortopedica brasileira. 2014 Dec;22(6):334-8.
  29. Hagberg M, Harms-Ringdahl K, Nisell R, Hjelm EW. Rehabilitation of neck-shoulder pain in women industrial workers: a randomized trial comparing isometric shoulder endurance training with isometric shoulder strength training. Archives of physical medicine and rehabilitation. 2000 Aug 1;81(8):1051-8.
  30. Zebis MK, Andersen LL, Pedersen MT, Mortensen P, Andersen CH, Pedersen MM, Boysen M, Roessler KK, Hannerz H, Mortensen OS, Sjøgaard G. Implementation of neck/shoulder exercises for pain relief among industrial workers: a randomized controlled trial. BMC musculoskeletal disorders. 2011 Dec;12(1):205.
  31. Ylinen J, Hakkinen A, Nykanen M, Kautiainen H, Takala E. Neck muscle training in the treatment of chronic neck pain: a three-year follow-up study. Europa medicophysica. 2007 Jun 1;43(2):161.
  32. Andersen LL, Blangsted AK, Nielsen PK, Hansen L, Vedsted P, Sjøgaard G, Søgaard K. Effect of cycling on oxygenation of relaxed neck/shoulder muscles in women with and without chronic pain. European journal of applied physiology. 2010 Sep 1;110(2):389-94.
  33. 33.0 33.1 33.2 33.3 Vernon H, Schneider M. Chiropractic management of myofascial trigger points and myofascial pain syndrome: a systematic review of the literature. Journal of manipulative and physiological therapeutics. 2009 Jan 1;32(1):14-24.
  34. Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM. Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials. The Lancet. 2009 Dec 5;374(9705):1897-908.
  35. Nunes AM, Moita JP. Effectiveness of physical and rehabilitation techniques in reducing pain in chronic trapezius myalgia: A systematic review and meta-analysis. International Journal of Osteopathic Medicine. 2015 Sep 30;18(3):189-206.
  36. 36.0 36.1 Aguilera FJ, Martín DP, Masanet RA, Botella AC, Soler LB, Morell FB. Immediate effect of ultrasound and ischemic compression techniques for the treatment of trapezius latent myofascial trigger points in healthy subjects: a randomized controlled study. Journal of manipulative and physiological therapeutics. 2009 Sep 1;32(7):515-20.
  37. Trapezius muscle image - © Kenhub https://www.kenhub.com/en/library/anatomy/trapezius-muscle