Rheumatoid Arthritis: Difference between revisions
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Rheumatoid arthritis (RA) is an autoimmune disease and a form of inflammatory arthritis that affects five or more joints. Autoimmune conditions occur when the body fights its own immune system. Instead of the immune system protecting the body, it attacks itself. In RA, the immune system attacks the lining of the joints, called the synovium. RA is a long-term disease that leads to inflammation of the joints and surrounding tissues and can also affect other organs. Symptoms may present as inflammation of joints, pain and fatigue. | Rheumatoid arthritis (RA) is an autoimmune disease and a form of inflammatory arthritis that affects five or more joints. Autoimmune conditions occur when the body fights its own immune system. Instead of the immune system protecting the body, it attacks itself. In RA, the immune system attacks the lining of the joints, called the synovium. RA is a long-term disease that leads to inflammation of the joints and surrounding tissues and can also affect other organs. Symptoms may present as inflammation of joints, pain and fatigue. | ||
The disease course typically follows three possible paths: <br>a. Monocyclic: Having one episode that does not reoccur. This usually ends within 2-5 years of initial diagnosis.<br>b. Polycyclic: The disease severity varies over the course of the progression of the condition. <br>c. Progressive: Condition continues to become more severe and non-remitting. | The disease course typically follows three possible paths: <br>a. Monocyclic: Having one episode that does not reoccur. This usually ends within 2-5 years of initial diagnosis.<br>b. Polycyclic: The disease severity varies over the course of the progression of the condition. <br>c. Progressive: Condition continues to become more severe and non-remitting. | ||
<ref>National Center for Biotechnology Information, U.S. National Library of Medicine. Disease fact sheet:http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001467/ (accessed 1 March 2013)</ref><ref>Arthritis Foundation. Disease fact sheet: http://www.arthritis.org/conditions-treatments/disease-center/rheumatoid-arthritis/ (accessed 25 February 2013).</ref><br><br> | <ref name="1">National Center for Biotechnology Information, U.S. National Library of Medicine. Disease fact sheet:http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001467/ (accessed 1 March 2013)</ref><ref name="2">Arthritis Foundation. Disease fact sheet: http://www.arthritis.org/conditions-treatments/disease-center/rheumatoid-arthritis/ (accessed 25 February 2013).</ref><br><br> | ||
== Prevalence == | == Prevalence == | ||
Revision as of 02:01, 4 March 2013
Original Editors -Amanda Fetz & Katie Robertson from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Lead Editors - Your name will be added here if you are a lead editor on this page. Read more.
Definition/Description[edit | edit source]
Rheumatoid arthritis (RA) is an autoimmune disease and a form of inflammatory arthritis that affects five or more joints. Autoimmune conditions occur when the body fights its own immune system. Instead of the immune system protecting the body, it attacks itself. In RA, the immune system attacks the lining of the joints, called the synovium. RA is a long-term disease that leads to inflammation of the joints and surrounding tissues and can also affect other organs. Symptoms may present as inflammation of joints, pain and fatigue.
The disease course typically follows three possible paths:
a. Monocyclic: Having one episode that does not reoccur. This usually ends within 2-5 years of initial diagnosis.
b. Polycyclic: The disease severity varies over the course of the progression of the condition.
c. Progressive: Condition continues to become more severe and non-remitting.
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Prevalence[edit | edit source]
The prevalence of Rheumatoid Arthritis is estimated between 1.5- 2.1 million US adults or 10 cases per every 1000 people. There are nearly three times as many women then men with the disease. RA is found all around the world, but does tend to be more prevalent in the Native American and white population.
The risk of RA increases with age. RA most commonly begins in women between the ages of 30 and 60. It often occurs later in life for men, but can happen at any age. When RA affects the pediatric population, it is called Juvenile Rheumatoid Arthritis (JIA) and usually begins before the age of 16.
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Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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References[edit | edit source]
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- ↑ CDC. Rheumatoid Arthritis.http://www.cdc.gov/arthritis/basics/rheumatoid.htm (accessed 13 February 2013).
