Retinoblastoma

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Top Contributors - Kapil Narale and Kim Jackson  

Introduction[edit | edit source]

Retinoblastoma is the most common ocular cancer that occurs in the pediatric population. It is lethal if it is left untreated. [1]

Epidemiology[edit | edit source]

In high-income countries, retinoblastoma is known to be a curable disease, with close to 100% chance of survival. However, in middle- and low-income countries, the prognosis is extremely low. In addition, more than 80% of cases occur in these countries. [1]

It is estimated that the majority of retinoblastoma cases occur in Asia (53%), then Africa (29%), Latin America (8%), North America (3%), and Europe (6%). With this information it is seen that global retinoblastoma patient survival is <30%. It is seen that the survival rate is 40% (23‑70%) in low‑income countries, while it is 79% (54‑93%) in upper‑middle‑income countries.

Treatment[edit | edit source]

Enucleation has been the preferred mode of treatment, for advanced retinoblastoma, in low-middle-income countries. however, over the last 30 years, the globe-savaging techniques have been used.

Although the management of retinoblastoma may differ from place ot place, and from clinic to clinic, the overall structure of treatment involves a similar framework.

Resources[edit | edit source]

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References[edit | edit source]

  1. 1.0 1.1 Ancona-Lezama D, Dalvin LA, Shields CL. Modern treatment of retinoblastoma: A 2020 review. Indian Journal of Ophthalmology. 2020:68:2356-2365.