Post-Stroke Pain

Original Editor - Carina Therese Magtibay

Top Contributors - Carina Therese Magtibay and Kim Jackson

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Introduction[edit | edit source]

Stroke is one of the primary causes of mortality and adult-onset disability globally.[1][2]Post-stroke pain is a common sequelae of stroke that can significantly reduce quality of life, potentially leading to depression, anxiety, sleep disorders and complicating rehabilitation.[3]Current research shows that post-stroke pain is under-reported and poorly understood.

Common post-stroke pain subtypes:

  • central post-stroke pain (CPSP)
  • pain secondary to spasticity
  • shoulder pain
  • complex regional pain syndrome (CRPS)
  • headache

Aetiology[edit | edit source]

Epidemiology[edit | edit source]

Risk factors for developing post-stroke pain:[3]

  • Demographic
    • Female sex
    • Older age at stroke onset
  • Premorbid
    • Alcohol use
    • Statin use
    • Peripheral vascular disease
    • Depression
  • Clinical features
    • Spasticity
    • Reduced upper extremity movement
    • Sensory deficits
  • Stroke-related
    • Ischemic stroke
    • Thalamic localization
    • Brainstem localization

Pathophysiology[edit | edit source]

Clinical Presentation[edit | edit source]

Diagnosis and Assessment[edit | edit source]

Pharmacological Management[edit | edit source]

Physiotherapy Management[edit | edit source]

Multi-disciplinary Approach[edit | edit source]

  1. Feigin VL, Abajobir AA, Abate KH, Abd-Allah F, Abdulle AM, Abera SF, Abyu GY, Ahmed MB, Aichour AN, Aichour I, Aichour MT. Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet Neurology. 2017 Nov 1;16(11):877-97.
  2. Avan A, Digaleh H, Di Napoli M, Stranges S, Behrouz R, Shojaeianbabaei G, Amiri A, Tabrizi R, Mokhber N, Spence JD, Azarpazhooh MR. Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017. BMC medicine. 2019 Dec;17(1):1-30.
  3. 3.0 3.1 Harrison RA, Field TS. Post stroke pain: identification, assessment, and therapy. Cerebrovascular diseases. 2015 Mar 5;39(3-4):190-201.