Osteoarthritis and Exercise

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Top Contributors - Nupur Smit Shah, Shaimaa Eldib and Lucinda hampton  

Introduction[edit | edit source]

Osteoarthritis is a common form of arthritis and it leads to a major health economic burden. It commonly occurs in weight bearing joints such as hip and knee , with knee joint being more often involved.[1]

In osteoarthritis, initially there is molecular derangement (interrupted joint metabolism) followed by anatomical and physiological derangements such as cartilage degeneration, osteophyte formation, bone remodeling, joint inflammation and loss of normal function. The overall risk of this condition is more in obese population and even those who had previous joint injury. It has been proved that knee joint pain is reduced when obese patients undergo weight reduction. Clinically the patients present with pain and stiffness in affected joint. Morning stiffness is also present.[2]

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References[edit | edit source]

  1. Funck‐Brentano T, Nethander M, Movérare‐Skrtic S, Richette P, Ohlsson C. Causal factors for knee, hip, and hand osteoarthritis: a Mendelian randomization study in the UK biobank. Arthritis & rheumatology. 2019 Oct;71(10):1634-41.
  2. Katz JN, Arant KR, Loeser RF. Diagnosis and treatment of hip and knee osteoarthritis: a review. Jama. 2021 Feb 9;325(6):568-78.