Non-Hodgkin's Lymphoma

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.

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Definition/Description

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Prevalence

(NHL can affect an age range of individuals. It is more common in middle aged adults between the ages of 40 to 60.)^red (NHL comprises a large group of lymphoid malignancies (about 30 different specific types) and affects over 67,000 people per year, making this the 5th most common cancer in the United States.)^green   (
B-cell lymphomas: account for approximately 85% of non-Hodgkin lymphomas in the United States.

• Diffuse large B-cell lymphoma: is one of the more common types on non-Hodgkin lymphoma in the U.S. and affects about 1 out of 3 cases.
• Follicular lymphoma: affects about 1 out of 5 cases of non-Hodgkin lymphoma in the U.S.
• Small lymphocytic lymphoma: accounts for about 5% to 10% of all lymphomas.
• Mantle cell lymphoma: accounts for about 5% of lymphomas.
• Marginal zone B-cell lymphomas: account for about 5% to 10% of lymphomas.
• Primary mediastinal B-cell lymphoma: accounts for about 2% of all lymphomas. About 2 out of 3 people with this type are females in their 30s.
• Burkitt lymphoma: accounts for about 1% to 2% of all lymphomas. Close to 90% of patients with this type are males in their 30s.
• Lymphoplasmacytic lymphoma: accounts for 1% to 2% of all lymphomas.
• Hairy cell leukemia: is rare but accounts for about 1,000 people in the U.S. each year.

T-cell lymphomas: account for less than 15% of non-Hodgkin lymphomas in the United States.

• Precursor T-lymphoblastic lymphoma/leukemia: accounts for about 1% of all lymphomas.
• Peripheral T-cell lymphomas: are comprised of 7 different types of lymphoma and account for about 5% of all lymphomas.)^ACS
  
  

    

Characteristics/Clinical Presentation

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Associated Co-morbidities

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Medications

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Diagnostic Tests/Lab Tests/Lab Values

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Causes

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Systemic Involvement

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Medical Management (current best evidence)

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Physical Therapy Management (current best evidence)

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Alternative/Holistic Management (current best evidence)

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Differential Diagnosis

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Case Reports

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Resources

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Recent Related Research (from Pubmed)

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References

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