Non-Hodgkin's Lymphoma: Difference between revisions
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<u>'''B-cell lymphomas'''</u>''':''' account for approximately 85% of non-Hodgkin lymphomas in the United States. <ref name="ACS">American Cancer Society. Detailed Guide: Lymphoma, Non-Hodgkin Type, What is Non-Hodgkin Lymphoma? American Cancer Society, Inc.; 2009-07-17; 2010-02. Available from: (http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_Is_Non_Hodgkins_Lymphoma)</ref><br> | <u>'''B-cell lymphomas'''</u>''':''' account for approximately 85% of non-Hodgkin lymphomas in the United States. <ref name="ACS">American Cancer Society. Detailed Guide: Lymphoma, Non-Hodgkin Type, What is Non-Hodgkin Lymphoma? American Cancer Society, Inc.; 2009-07-17; 2010-02. Available from: (http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_Is_Non_Hodgkins_Lymphoma)</ref><br> | ||
*<u>Diffuse large B-cell lymphoma</u>: is one of the more common types on non-Hodgkin lymphoma in the U.S. and affects about 1 out of 3 cases. | *<u>Diffuse large B-cell lymphoma</u>: is one of the more common types on non-Hodgkin lymphoma in the U.S. and affects about 1 out of 3 cases (or 33%). | ||
*<u>Follicular lymphoma</u>: affects about 1 out of 5 cases of non-Hodgkin lymphoma in the U.S. | *<u>Follicular lymphoma</u>: affects about 1 out of 5 cases of non-Hodgkin lymphoma in the U.S. | ||
*<u>Small lymphocytic lymphoma</u>: accounts for about 5% to 10% of all lymphomas. | *<u>Small lymphocytic lymphoma</u>: accounts for about 5% to 10% of all lymphomas. | ||
Revision as of 19:02, 4 March 2010
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Definition/Description[edit | edit source]
Non-Hodgkin's lymphoma (NHL) is "a group of lymphomas affecting lymphoid tissue and occuring in persons of all ages."[1] "The lymphoid malignancies present as solid tumors arising from cells of the lymphatic system. The lymph nodes are ususally involved first, and any extranodal lymphoid tissue, particularly the spleen, thymus, and GI tract, may also be involved. The bone marrow is commonly infiltrated by lymphoma cells, but this is rarely the primary site of a lymphoma.
Lymphomas are classified according to the World Health Organization (WHO) which relies on the histochemical, genetic and cytologic features of the cells. Lymphomas are classified as either B-cell or T-cell lymphomas."[2]
Prevalence[edit | edit source]
"NHL can affect any age range of individuals. It is more common in middle aged adults between the ages of 40 to 60."[1] "NHL comprises a large group of lymphoid malignancies (about 30 different specific types) and affects over 67,000 people per year, making this the 5th most common cancer in the United States."[2]
B-cell lymphomas: account for approximately 85% of non-Hodgkin lymphomas in the United States. [3]
- Diffuse large B-cell lymphoma: is one of the more common types on non-Hodgkin lymphoma in the U.S. and affects about 1 out of 3 cases (or 33%).
- Follicular lymphoma: affects about 1 out of 5 cases of non-Hodgkin lymphoma in the U.S.
- Small lymphocytic lymphoma: accounts for about 5% to 10% of all lymphomas.
- Mantle cell lymphoma: accounts for about 5% of lymphomas.
- Marginal zone B-cell lymphomas: account for about 5% to 10% of lymphomas.
- Primary mediastinal B-cell lymphoma: accounts for about 2% of all lymphomas. About 2 out of 3 people with this type are females in their 30s.
- Burkitt lymphoma: accounts for about 1% to 2% of all lymphomas. Close to 90% of patients with this type are males in their 30s.
- Lymphoplasmacytic lymphoma: accounts for 1% to 2% of all lymphomas.
- Hairy cell leukemia: is rare but accounts for about 1,000 people in the U.S. each year.
T-cell lymphomas: account for less than 15% of non-Hodgkin lymphomas in the United States. [3]
- Precursor T-lymphoblastic lymphoma/leukemia: accounts for about 1% of all lymphomas.
- Peripheral T-cell lymphomas: are comprised of 7 different types of lymphoma and account for about 5% of all lymphomas.
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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- ↑ 1.0 1.1 Goodman, Snyder. Differential Diagnosis for Physical Therapists: Screening for Referral. 4th Ed. Philadelphia: WB Saunders; 2003.
- ↑ 2.0 2.1 Goodman C.C., Fuller, K.S. Pathology: Implications for the Physical Therapist. 3rd Ed. Missouri, Saunders & Elsevier; 2009.
- ↑ 3.0 3.1 American Cancer Society. Detailed Guide: Lymphoma, Non-Hodgkin Type, What is Non-Hodgkin Lymphoma? American Cancer Society, Inc.; 2009-07-17; 2010-02. Available from: (http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_Is_Non_Hodgkins_Lymphoma)
