NSAID Gastropathy: Difference between revisions
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== Medical Management (current best evidence) == | == Medical Management (current best evidence) == | ||
The best management for NSAID-related gastropathy is discontinued use of the NSAID. However, if this is not possible, one alternative is to prescribe a medication that reduces the gastric effects such as a PPI or an H2-receptor antagonist. The use of a PPI along with NSAIDs has shown the most positive results for prevention of NSAID-related ulcers. Futhermore, a COX-2 selective NSAID along with a PPI has shown the best results. Other treatment options include misoprostol which is a synthetic prostaglandin designed to replace those loss by NSAIDs. However, misoprotol has a lot of side effects that have proved difficult such as abdominal pain, nausea, diarrhea, and it should be avoided in pregnant women.<br> | |||
== Physical Therapy Management (current best evidence) == | == Physical Therapy Management (current best evidence) == | ||
Revision as of 14:55, 10 March 2013
Original Editors - Amanda Huber & Emily Sipe from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
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Prevalence[edit | edit source]
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
The best management for NSAID-related gastropathy is discontinued use of the NSAID. However, if this is not possible, one alternative is to prescribe a medication that reduces the gastric effects such as a PPI or an H2-receptor antagonist. The use of a PPI along with NSAIDs has shown the most positive results for prevention of NSAID-related ulcers. Futhermore, a COX-2 selective NSAID along with a PPI has shown the best results. Other treatment options include misoprostol which is a synthetic prostaglandin designed to replace those loss by NSAIDs. However, misoprotol has a lot of side effects that have proved difficult such as abdominal pain, nausea, diarrhea, and it should be avoided in pregnant women.
Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports/ Case Studies[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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- ↑ Lanza F. A guideline for the treatment and prevention of NSAID-induced ulcers. Members of the Ad Hoc Committee on Practice Parameters of the American College of Gastroenterology. The American Journal Of Gastroenterology [serial on the Internet]. (1998, Nov),93(11): 2037-2046. Available from: MEDLINE. ..
