Hypoxic Ischemic Encephalopathy: Difference between revisions

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== Clinical Presentation  ==
== Clinical Presentation  ==


add text here relating to the clinical presentation of the condition<br>  
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== Diagnostic Procedures  ==
== Diagnostic Procedures  ==

Revision as of 06:52, 7 February 2022

Original Editor - User Name Top Contributors - Lauren Heydenrych and Manisha Shrestha
Original Editor - User Name
Top Contributors - Lauren Heydenrych and Manisha Shrestha

Introduction[edit | edit source]

Hypoxic Ischemic Encephalopathy (HIE) is a condition in which injury to the brain of neonate occur following deprivation of oxygen supply to brain. [1]It is the common cause of neonate mortality and developmental psychomotor disorders in the pediatric worldwide.[2]

Epidemiology[edit | edit source]

  • The incidence of HIE is ~1–8 per 1,000 live births in technically advanced countries and is up to 26 per 1,000 live births in less developed countries.[2]

Mechanism of Injury / Pathological Process[edit | edit source]

File: Schematic overview of the phases of injury in Hypoxic-Ischemic Encephalopathy (HIE), adapted from Douglas-Escobar et al. and Hassell et al..jpg


Clinical Presentation[edit | edit source]


Diagnostic Procedures[edit | edit source]

add text here relating to diagnostic tests for the condition

Outcome Measures[edit | edit source]

add links to outcome measures here (see Outcome Measures Database)

Management / Interventions
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add text here relating to management approaches to the condition

Differential Diagnosis
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add text here relating to the differential diagnosis of this condition

Resources
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add appropriate resources here

References[edit | edit source]

  1. Greco P, Nencini G, Piva I, Scioscia M, Volta CA, Spadaro S, Neri M, Bonaccorsi G, Greco F, Cocco I, Sorrentino F. Pathophysiology of hypoxic–ischemic encephalopathy: a review of the past and a view on the future. Acta Neurologica Belgica. 2020 Apr;120(2):277-88.
  2. 2.0 2.1 Kleuskens DG, Goncalves Costa F, Annink KV, van den Hoogen A, Alderliesten T, Groenendaal F, Benders MJ, Dudink J. Pathophysiology of cerebral hyperperfusion in term neonates with hypoxic-ischemic encephalopathy: A systematic review for future research. Frontiers in pediatrics. 2021:17.