Hypoxic Ischemic Encephalopathy: Difference between revisions

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== Clinically Relevant Anatomy<br> ==
== Introduction ==
Hypoxic Ischemic Encephalopathy (HIE) is a condition in which injury to the brain of neonate occur following deprivation of oxygen supply to brain. <ref>Greco P, Nencini G, Piva I, Scioscia M, Volta CA, Spadaro S, Neri M, Bonaccorsi G, Greco F, Cocco I, Sorrentino F. [https://link.springer.com/article/10.1007/s13760-020-01308-3 Pathophysiology of hypoxic–ischemic encephalopathy: a review of the past and a view on the future.] Acta Neurologica Belgica. 2020 Apr;120(2):277-88.</ref>It is the common cause of neonate mortality and developmental psychomotor disorders in the pediatric worldwide.<ref name=":0">Kleuskens DG, Goncalves Costa F, Annink KV, van den Hoogen A, Alderliesten T, Groenendaal F, Benders MJ, Dudink J. [https://www.frontiersin.org/articles/10.3389/fped.2021.631258/full Pathophysiology of cerebral hyperperfusion in term neonates with hypoxic-ischemic encephalopathy: A systematic review for future research.] Frontiers in pediatrics. 2021:17.</ref>


add text here relating to '''''clinically relevant''''' anatomy of the condition<br>
== Epidemiology ==


== Mechanism of Injury / Pathological Process<br> ==
* The incidence of HIE is ~1–8 per 1,000 live births in technically advanced countries and is up to 26 per 1,000 live births in less developed countries.<ref name=":0" />
*


add text here relating to the mechanism of injury and/or pathology of the condition<br>  
== Mechanism of Injury / Pathological Process ==
[[File:Schematic overview of the phases of injury in Hypoxic-Ischemic Encephalopathy (HIE), adapted from Douglas-Escobar et al. and Hassell et al..jpg|center|frameless|573x573px|'''File: Schematic overview of the phases of injury in Hypoxic-Ischemic Encephalopathy (HIE), adapted from Douglas-Escobar et al. and Hassell et al..jpg''']]
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== Clinical Presentation  ==
== Clinical Presentation  ==
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<references />
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[[Category:Paediatrics - Conditions]]
[[Category:Paediatrics]]

Revision as of 05:42, 7 February 2022

Original Editor - User Name Top Contributors - Lauren Heydenrych and Manisha Shrestha
Original Editor - User Name
Top Contributors - Lauren Heydenrych and Manisha Shrestha

Introduction[edit | edit source]

Hypoxic Ischemic Encephalopathy (HIE) is a condition in which injury to the brain of neonate occur following deprivation of oxygen supply to brain. [1]It is the common cause of neonate mortality and developmental psychomotor disorders in the pediatric worldwide.[2]

Epidemiology[edit | edit source]

  • The incidence of HIE is ~1–8 per 1,000 live births in technically advanced countries and is up to 26 per 1,000 live births in less developed countries.[2]

Mechanism of Injury / Pathological Process[edit | edit source]

File: Schematic overview of the phases of injury in Hypoxic-Ischemic Encephalopathy (HIE), adapted from Douglas-Escobar et al. and Hassell et al..jpg


Clinical Presentation[edit | edit source]

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Diagnostic Procedures[edit | edit source]

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Outcome Measures[edit | edit source]

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Management / Interventions
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Differential Diagnosis
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Resources
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References[edit | edit source]

  1. Greco P, Nencini G, Piva I, Scioscia M, Volta CA, Spadaro S, Neri M, Bonaccorsi G, Greco F, Cocco I, Sorrentino F. Pathophysiology of hypoxic–ischemic encephalopathy: a review of the past and a view on the future. Acta Neurologica Belgica. 2020 Apr;120(2):277-88.
  2. 2.0 2.1 Kleuskens DG, Goncalves Costa F, Annink KV, van den Hoogen A, Alderliesten T, Groenendaal F, Benders MJ, Dudink J. Pathophysiology of cerebral hyperperfusion in term neonates with hypoxic-ischemic encephalopathy: A systematic review for future research. Frontiers in pediatrics. 2021:17.